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Nowadays, medicinal plants used in folk medicine are increasingly studied and used on pharmaceutical, food and nutraceutical fields, wormwood Artemisia herba -alba is one of traditional medical characterized by scientists of preservation its wealth in different composition which led to the definition of several chemotypes the main objectives of this work were to evaluate the antioxidant activity of aerial part of wormwood, the plant had been refractive index of the order of 0.911 and 1.66.The qualitative and quantitive phytochemicals detected were alkaloids, tannis, saponin, flavonoids, phenolic compounds and carbohydrates in moderate amount (12.8, 9.42, 10.65, 6.8 and 11.5) respectively. Antibacterial activities of ethanolic extract the weeds was determined against clinical isolates of Staphylococcus aureus, Proteus vulgaris, Escherichia Coli, Pseudomonas aeruginosa, the results revealed a potential antibacterial activity against pathogenic bacteria, The activity of ethanolic extract had been highest an Minimal inhibitory concentration of 50 mg mlˉ¹against Staphylococcus aureus had 4.7 cfu mlˉ¹, and lowest in E.coli had 2.8 cfu mlˉ¹. The results it could be extracted that wormwood possesed an interesting effects and had been promising use as a natural source of antioxidant and antibacterial agents.