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In a warming world, urban environmental stresses are exacerbated by population-increase-induced development of grey infrastructure that usually leaves minimal scope for blue (and green) elements and processes, potentially resulting in mismanagement of stormwater and flooding issues. This paper explores how urban growth planning in the megacity of Dhaka, Bangladesh can be guided by a blue-green infrastructure (BGI) network that combines blue, green, and grey elements together to provide a multifunctional urban form. We take a three-step approach: First, we analyze the existing spatial morphology to understand potential locations of development and challenges, as well as the types of solutions necessary for water management in different typologies of urban densities. Next, we analyze existing and potential blue and green network locations. Finally, we propose the structural framework for a BGI network at both macro and micro scales. The proposed network takes different forms at different scales and locations and offers different types of flood control and stormwater management options. These can provide directions on Dhaka’s future urban consolidation and expansion with a balance of man-made and natural elements and enable environmental, social, spatial, financial, and governance benefits. The paper concludes with some practical implications and challenges for implementing BGI in Dhaka.

Background Although physical frailty has long been recognized as a clinical condition, it has only recently gained attention in Bangladesh. This growing interest reflects the country’s increasing focus on the health challenges faced by its aging population. This study examined the prevalence of physical frailty and its association with cognitive impairment among older adults. Methods The study used a cross-sectional design conducted among 540 older adults aged 65 and above using a multistage sampling technique. Physical frailty status was assessed using the Fried frailty phenotype, and cognitive function was measured with the 30-item Mini-Mental State Examination. Results Across two districts, 60% of participants were classified as frail, and 33% were classified as pre-frail. Significant demographic differences were observed across frailty categories, including age, gender, marital status, net monthly income level, and smoking history ( p  < 0.001). Multinomial logistic regression analyses indicated that several demographic and clinical factors were associated with cognitive impairment, including gender, education, household income, and multimorbidity. Higher household income (> 60,000 Bangladeshi Taka [BDT] per month) was associated with lower odds of severe cognitive impairment (OR = 0.14, 95% CI = 0.04, 0.45). Regular visits from family or friends showed a suggestive association with lower odds of cognitive impairment (OR = 0.59, 95% CI = 0.03, 1.54), although this association did not reach statistical significance at the 0.05 level. Cognitive function tended to be lower among frail participants aged 81 and above, with the lowest observed scores. Conclusion The findings demonstrate a significant association between physical frailty and cognitive impairment among older adults in Bangladesh, emphasizing the role of social determinants in shaping these outcomes. The results highlight the need for targeted interventions and policy strategies addressing these determinants to promote healthy aging and mitigate cognitive decline in this population.

Those with diabetes mellitus are at high-risk of developing psychiatric disorders, especially mood disorders, yet the link between hyperglycemia and altered motivation has not been thoroughly explored. Here, we characterized value-based decision-making behavior of a streptozocin-induced diabetic mouse model on Restaurant Row, a naturalistic neuroeconomic foraging paradigm capable of behaviorally capturing multiple decision systems known to depend on dissociable neural circuits. Mice made self-paced choices on a daily limited time-budget, accepting or rejecting reward offers based on cost (delays cued by tone pitch) and subjective value (flavors), in a closed-economy system tested across months. We found streptozocin-treated mice disproportionately undervalued less-preferred flavors and inverted their meal-consumption patterns shifted toward a more costly strategy overprioritizing high-value rewards. These foraging behaviors were driven by impairments in multiple decision-making processes, including the ability to deliberate when engaged in conflict and cache the value of the passage of time as sunk costs. Surprisingly, diabetes-induced changes in motivation depended not only on the type of choice being made, but also on the salience of reward-scarcity in the environment. These findings suggest that complex relationships between metabolic dysfunction and dissociable valuation algorithms underlying unique cognitive heuristics and sensitivity to opportunity costs can disrupt distinct computational processes leading to comorbid psychiatric vulnerabilities. A neuroeconomic approach to characterize decision-making behavior reveals alterations in distinct valuation algorithms in a mouse model of diabetes, shedding light on the interaction between metabolic disorders, energy balance, and cognitive heuristics.

Background Women's sexual health and physical desire for sex are most important for their emotional and physical well-being. This study aimed to examine the status of sexual dysfunction among postmenopausal women in Bangladesh and assess the significant risk factors behind this. Methods A cross-sectional study was conducted among 45–55 years in four public and private hospitals in Bangladesh from April 2021 to June 2021 using a multi-stage sampling technique to enroll the study participants. The female sexual function index (FSFI) scale measured the prevalence of FSD, and the relationship of independent risk factors were assessed using a multivariate logistic regression model. Results The total score of FSFI among postmenopausal Bangladeshi women was 18.07 ± 8.51. Among 260 participants, the prevalence of FSD was 56.9%. Out of all the significant risk factors, increasing age, urban population group, multiparous, homemakers, duration of menopause, and postmenopausal women with no hormone therapy were significantly associated with FSD. In contrast, those with regular physical activity were protective of FSD. Conclusion In conclusion, a significant proportion of postmenopausal Bangladeshi women are enduring sexual dysfunction. Proper hormonal therapy and non-hormonal therapies such as physical activity and pelvic floor muscle (Kegel) exercise with adequate counseling are helpful to cope in this distressing situation.

BackgroundHabits are obtained as a consequence of cue-contingent behavioural repetition. Context cues stimulate strong habits without an individual contemplating that action has been initiated. Because of its health-enhancing effects, making physical activity a part of one’s life is essential. This study examined the associations of physical activity (PA) behaviours with PA habits and the role of autonomous motivation in developing PA habits.MethodsThis study used a cross-sectional design. A structured questionnaire was implemented through emails to 226 university students, where PA levels, habits and autonomous motivation were self-reported.ResultsBinary logistic regression identified age groups, gender and participants who were trying to lose weight as the significant predictors in meeting physical activity guidelines. Path analysis showed that moderate-intensity physical activity (β = 0.045, CI = 0.069–0.248) and strength training exercises (β = 0.133, CI = 0.148–0.674) were significantly associated with PA habits (p < 0.01). Autonomous motivation was directly associated with PA habits (β = 0.062, CI = [0.295–0.541], p < 0.01) and was also significantly related to moderate-intensity physical activity (β = 0.243, CI = [0.078–0.266], p < 0.01) and strength training exercises (β = 0.202, CI = [0.033–0.594], p < 0.05).ConclusionsThe emphasis on experiment-based logic and interest in habit formation in the research community is extensive. As the college years offer an excellent opportunity to establish healthy behavioural interventions, encouraging students in regular PA and exhibiting an autonomous motivation towards PA may be necessary.

Community energy systems are an emerging concept which aims to re-organize the local energy system through efficient integration of Distributed Energy Resources (DERs) and engagement of local communities. A better understanding of the possible benefits of deployed DERs such as community energy storage systems is therefore required, along with an active energy management system within the control framework of community smart-grids, in order to integrate and optimize the operation of flexible resources within the energy communities. An efficient model of a community energy management system is proposed in this thesis for communities equipped with grid-connected PV and Battery Energy Storage System (BESS). An algorithm is developed which controls the power flow between the electricity end-users, the communal BESS and the power grid, based on historical and instantaneous PV generation and load consumption data attained from three real communities in the UK. Increased accessibility to smart-meters and market availability of Time-of-Use electricity tariff schemes, which amplifies off-peak/peak cost difference, are exploited to achieve energy cost minimization for energy end-users in the communities through energy-shifting and increment of PV self-consumption. The methods of choosing a battery size which balances the trade-off between increasing battery capacity and reducing system cost is demonstrated and their impact on the annual household electricity cost is assessed. Similarly the effects on energy loss and cost saving by choosing converter ratings which are lower than the maximum power of the system is demonstrated and using a method of power-bins, the rating is determined for each community. Assessment has been done on communities in the UK to develop an algorithm for a Community Power Flow Battery Management System (CPF BMS), and to better understand the benefits that battery energy storage, in particular centrally controlled systems, can bring to an energy community. The operation of loads clustered as a community as opposed to individual users has been assessed and the results show that community operation achieves higher energy cost savings. It also allowed for larger optimum battery and converter sizes, which in turn allows higher self-consumption of local PV generation, better energy-shifting from off-peak hours to high-tariff band periods through battery storage, and finally lower energy bills. This project contributes to the increasing number of technologies and business models focusing on the decarbonisation of the energy sector through cost reduction incentives to the electricity end-users, and empowering the community to have a greater control of their energy usage and resources.

Introduction During the COVID-19 pandemic, self-medication (SM) has become a critical element in the healthcare system. SM can ease the burden on hospitals and medical resources by treating minor illnesses. However, inappropriate SM practices can lead to adverse drug reactions, drug resistance, and incorrect diagnoses, resulting in poor health outcomes. Methods To evaluate the prevalence, knowledge, causes, and practices of SM among the Bangladeshi population during the COVID-19 outbreak, a cross-sectional survey with structured questionnaires was conducted in Chittagong City, Bangladesh, from March to May 2022. The survey included 265 participants, with an average age of 35.09 years, and a multiple-choice questionnaire was used to gather information. Results The study found that 64.15% of the respondents had sufficient knowledge of SM, while 35.8% had insufficient knowledge. The primary reasons for SM during the pandemic were the influence of friends/family (90.74%), fear of infection or contact with COVID-19 cases (73.15%), and fear of quarantine or self-isolation (72.22%). Analgesics/pain relievers (84%) were the most commonly used drugs for SM for COVID-19 prevention and treatment. Antiulcerants/antacid (42%), vitamin C and multivitamins (42%), and antibiotics (32%) were also frequently used. Conclusion This study suggests that SM is prevalent among Chittagong City residents, particularly those with less than a tertiary education. The study highlights the importance of building awareness about SM practices and taking necessary steps to control them.

Changing one's mind is a complex cognitive phenomenon involving a continuous re-appraisal of the trade-off between past costs and future value. Recent work modeling this behavior across species has established associations between aspects of this choice process and their contributions to altered decision-making in psychopathology. Here, we investigated the actions in medial prefrontal cortex (mPFC) neurons of long intergenic non-coding RNA, LINC00473, known to induce stress resilience in a striking sex-dependent manner, but whose role in cognitive function is unknown. We characterized complex decision-making behavior in male and female mice longitudinally in our neuroeconomic foraging paradigm, Restaurant Row, following virus-mediated LINC00473 expression in mPFC neurons. On this task, mice foraged for their primary source of food among varying costs (delays) and subjective value (flavors) while on a limited time-budget during which decisions to accept and wait for rewards were separated into discrete stages of primary commitments and secondary re-evaluations. We discovered important differences in decision-making behavior between female and male mice. LINC00473 expression selectively influenced multiple features of re-evaluative choices, without affecting primary decisions, in female mice only. These behavioral effects included changing how mice (i) cached the value of the passage of time and (ii) weighed their history of economically disadvantageous choices. Both processes were uniquely linked to change-of-mind decisions and underlie the computational bases of distinct aspects of counterfactual thinking. These findings reveal a key bridge between a molecular driver of stress resilience and psychological mechanisms underlying sex-specific decision-making proclivities.Changing one's mind is a complex cognitive phenomenon involving a continuous re-appraisal of the trade-off between past costs and future value. Recent work modeling this behavior across species has established associations between aspects of this choice process and their contributions to altered decision-making in psychopathology. Here, we investigated the actions in medial prefrontal cortex (mPFC) neurons of long intergenic non-coding RNA, LINC00473, known to induce stress resilience in a striking sex-dependent manner, but whose role in cognitive function is unknown. We characterized complex decision-making behavior in male and female mice longitudinally in our neuroeconomic foraging paradigm, Restaurant Row, following virus-mediated LINC00473 expression in mPFC neurons. On this task, mice foraged for their primary source of food among varying costs (delays) and subjective value (flavors) while on a limited time-budget during which decisions to accept and wait for rewards were separated into discrete stages of primary commitments and secondary re-evaluations. We discovered important differences in decision-making behavior between female and male mice. LINC00473 expression selectively influenced multiple features of re-evaluative choices, without affecting primary decisions, in female mice only. These behavioral effects included changing how mice (i) cached the value of the passage of time and (ii) weighed their history of economically disadvantageous choices. Both processes were uniquely linked to change-of-mind decisions and underlie the computational bases of distinct aspects of counterfactual thinking. These findings reveal a key bridge between a molecular driver of stress resilience and psychological mechanisms underlying sex-specific decision-making proclivities.

Changing one's mind involves re-appraisals between past-costs versus future-value and may be altered in psychopathology. Long intergenic non-coding RNA LINC00473 in medial prefrontal cortex (mPFC) can induce stress-resilience in a sex-dependent manner, but its role in cognition is unknown. We characterized decision-making behavior in male and female mice in the neuroeconomic paradigm Restaurant Row following virus-mediated expression of LINC00473 in mPFC. Mice foraged for food among varying temporal-costs and subjective-value while on a limited time-budget. Without affecting primary deliberative decisions, LINC00473 selectively influenced re-evaluative choices in a sex-dependent manner. This included changing how mice (i) cached value with the passage of time and (ii) weighed prior mistakes, which underlie the computational bases of sensitivity to sunk costs and regret. These findings suggest a common value function is shared between these neuroeconomic processes and reveal a bridge between molecular drivers of stress-resilience and psychological mechanisms underlying sex-specific proclivities in negative rumination.