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Cysticercosis is a neglected zoonotic disease caused by the larval stages of Taenia asiatica, T. saginata and T. solium. Its prevalence varies across regions, with limited data available in South Africa, particularly in Mpumalanga province. This study aimed to determine the seroprevalence and distribution of bovine and porcine cysticercosis in rural communities of Mpumalanga province, South Africa. A cross-sectional survey was conducted from 2021 to 2022 in Ehlanzeni and Nkangala districts. Blood samples were collected from 384 cattle and 336 pigs and analysed using the Apdia® cysticercosis AgELISA kit. Logistic regression was used to estimate odds of infection, with statistical significance set at p  0.05. Overall seroprevalence of bovine cysticercosis was 35.2% (95% confidence interval [CI]: 30.5–40.2), while porcine cysticercosis was 4.8% (95% CI: 2.8–7.6). Seroprevalence varied across districts and municipalities in Mpumalanga province, with evidence of spatial heterogeneity in both cattle and pigs. The higher prevalence in cattle is likely because of free-range grazing practices, increasing exposure to Taenia-contaminated environments. Pigs, mostly penned, had lower infection rates.Contribution: This study provides the first baseline data on bovine and porcine cysticercosis in Mpumalanga province, highlighting the need for improved livestock management, sanitation, farmer education and targeted surveillance to reduce transmission.

As pediatric populations in the United States (US) become increasingly diverse, current practices for interpreting bone density using DXA in children warrant reevaluation. The International Society for Clinical Densitometry currently recommends adjusting pediatric bone density Z-scores by race, sex, and age. However, race-based adjustments risk reinforcing disparities and perpetuating systemic inequities in pediatric bone health assessment. We conducted a scoping review of studies examining racial and ethnic differences in BMD among healthy US children, identifying 3960 records across 4 databases, of which 54 met inclusion criteria. Across these studies, reporting of race and ethnicity was inconsistent: although nearly all relied on self- or parent-report, none provided explicit definitions, and only 13% confirmed concordance across grandparents. Fifty percent of studies reported statistically significant racial differences in BMD, yet most did so without comprehensive covariate adjustment. By contrast, studies that accounted for height, lean mass, and pubertal status frequently found that differences attenuated or disappeared. These findings underscore the need to critically reconsider race-based adjustments in pediatric DXA interpretation. Developing and validating race-neutral reference standards, with attention to structural determinants and biologically relevant measures, such as stature, body composition, and pubertal timing, is essential for achieving a more equitable and clinically meaningful assessment of pediatric bone health.

The ongoing escalation of drug-resistant bacteria creates the leading challenges for human health. Current predictions show that deaths due to bacterial illness will be more in comparison to cancer in 2050. Irrational use of antibiotics, prolonged regimen and using as a prophylactic treatment for various infections are leading cause of microbial resistance. It is an emerging approach to introduce evolving nanomaterials (NMs) as a base of antibacterial therapy to overcome the bacterial resistance pattern. NMs can implement several bactericidal ways and turn into a challenge for bacteria to survive and develop resistance against NMs. All the pathways depend on the surface chemistry, shape, core material and size of NMs. Because of these reasons, NMs based stuff shows a critical role in advancing the treatment efficiency by interacting with the cellular system of bacteria and functioned as an antibiotic substitute. We divided this review into two sections. The first part highlights the development of microbial resistance to antibiotics and their mechanisms. The second section details the NMs mechanisms to combat antibiotic resistance. In short, we try to summarize the advances in NMs role to deal with microbial resistance and giving solution as antibiotics substitute.

Cryptography is commonly used to secure communication and data transmission over insecure networks through the use of cryptosystems. A cryptosystem is a set of cryptographic algorithms offering security facilities for maintaining more cover-ups. A substitution-box (S-box) is the lone component in a cryptosystem that gives rise to a nonlinear mapping between inputs and outputs, thus providing confusion in data. An S-box that possesses high nonlinearity and low linear and differential probability is considered cryptographically secure. In this study, a new technique is presented to construct cryptographically strong 8×8 S-boxes by applying an adjacency matrix on the Galois field GF (2 8 ). The adjacency matrix is obtained corresponding to the coset diagram for the action of modular group P S L ( 2 , Z ) on a projective line PL ( F 7 ) over a finite field F 7 . The strength of the proposed S-boxes is examined by common S-box tests, which validate their cryptographic strength. Moreover, we use the majority logic criterion to establish an image encryption application for the proposed S-boxes. The encryption results reveal the robustness and effectiveness of the proposed S-box design in image encryption applications.

The pollution of soil and aquatic systems by inorganic and organic chemicals has become a global concern. Economical, eco-friendly, and sustainable solutions are direly required to alleviate the deleterious effects of these chemicals to ensure human well-being and environmental sustainability. In recent decades, biochar has emerged as an efficient material encompassing huge potential to decontaminate a wide range of pollutants from soil and aquatic systems. However, the application of raw biochars for pollutant remediation is confronting a major challenge of not getting the desired decontamination results due to its specific properties. Thus, multiple functionalizing/modification techniques have been introduced to alter the physicochemical and molecular attributes of biochars to increase their efficacy in environmental remediation. This review provides a comprehensive overview of the latest advancements in developing multiple functionalized/modified biochars via biological and other physiochemical techniques. Related mechanisms and further applications of multiple modified biochar in soil and water systems remediation have been discussed and summarized. Furthermore, existing research gaps and challenges are discussed, as well as further study needs are suggested. This work epitomizes the scientific prospects for a complete understanding of employing modified biochar as an efficient candidate for the decontamination of polluted soil and water systems for regenerative development.

PurposeAs large multinational firms are increasingly tasked with developing sustainable supply chains, their role in improving the sustainability performance of their suppliers is critical. This paper examines the dual role of a buyer firm, as a customer and as an important stakeholder, and identifies several attributes of the buyer firm and the dyadic relationship that could help improve the sustainability performance of suppliers.Design/methodology/approachA dyadic multi-year dataset is created using financial and customer data from the Compustat database and sustainability data from MSCI ESG ratings database. The hypotheses are tested using econometric panel data techniques.FindingsThe findings indicate that a buyer's legitimacy is a key factor that affects supplier's sustainability performance. The effect of legitimacy is much higher when the buyer and supplier firms have an aligned focus on similar sustainability dimensions. The market power of the buyer also increases the effect of legitimacy, though power without legitimacy is not effective.Originality/valueThe study expands the understanding of how buyer firms can influence suppliers on sustainability by highlighting the key role played by legitimacy and aligned focus and the supporting role of market power. The study contributes to both the stakeholder salience literature and the buyer–supplier relationship literature by showing evidence for complementarity between market power and legitimacy. Buyer firms can use the results of the study to focus their efforts on suppliers where a significant improvement in sustainability can be expected.

The emergence of the Internet of Things (IoT) technology has brought about tremendous possibilities, but at the same time, it has opened up new vulnerabilities and attack vectors that could compromise the confidentiality, integrity, and availability of connected systems. Developing a secure IoT ecosystem is a daunting challenge that requires a systematic and holistic approach to identify and mitigate potential security threats. Cybersecurity research considerations play a critical role in this regard, as they provide the foundation for designing and implementing security measures that can address emerging risks. To achieve a secure IoT ecosystem, scientists and engineers must first define rigorous security specifications that serve as the foundation for developing secure devices, chipsets, and networks. Developing such specifications requires an interdisciplinary approach that involves multiple stakeholders, including cybersecurity experts, network architects, system designers, and domain experts. The primary challenge in IoT security is ensuring the system can defend against both known and unknown attacks. To date, the IoT research community has identified several key security concerns related to the architecture of IoT systems. These concerns include issues related to connectivity, communication, and management protocols. This research paper provides an all-inclusive and lucid review of the current state of anomalies and security concepts related to the IoT. We classify and analyze prevalent security distresses regarding IoT’s layered architecture, including connectivity, communication, and management protocols. We establish the foundation of IoT security by examining the current attacks, threats, and cutting-edge solutions. Furthermore, we set security goals that will serve as the benchmark for assessing whether a solution satisfies the specific IoT use cases.

Technology is transforming global trade. The global trading system, however, has struggled to keep up with changes in technology. One of the major challenges for the trading system is that the issues raised by digitally enabled commerce are largely regulatory in nature. The issues that are at the forefront of digital trade increasingly relate to citizens’ most fundamental interactions, including speech, finance, energy, and transportation. This paper argues that resolving these international regulatory issues will require reforming the approach that has been taken to global trade negotiations. International discussions around the most challenging issues in the digital economy ought to move away from the ‘horse-trading’ nature of traditional trade negotiations and towards a strategy focused on regulatory cooperation. Failure to achieve regulatory cooperation could further fragment digital services based upon national borders. The Internet has the potential to positively impact the global economy precisely because it is global, decentralized, and bottom-up in nature. International policymaking through regulatory cooperation can maintain those principles, while protecting fundamental national concerns such as stability, privacy, and security.

The platform of a microscopic traffic simulation provides an opportunity to study the driving behavior of vehicles on a roadway system. Compared to traditional conventional cars with human drivers, the car-following behaviors of autonomous vehicles (AVs) and connected autonomous vehicles (CAVs) would be quite different and hence require additional modeling efforts. This paper presents a thorough review of the literature on the car-following models used in prevalent micro-simulation tools for vehicles with both human and robot drivers. Specifically, the car-following logics such as the Wiedemann model and adaptive cruise control technology were reviewed based on the vehicle’s dynamic behavior and driving environments. In addition, some of the more recent “AV-ready (autonomous vehicles ready) tools” in micro-simulation platforms are also discussed in this paper.

The scientific advancements in the vehicle and infrastructure automation industry are progressively improving nowadays to provide benefits for the end-users in terms of traffic congestion reduction, safety enhancements, stress-free travels, fuel cost savings, and smart parking, etc. The advances in connected, autonomous, and connected autonomous vehicles (CV, AV, and CAV) depend on the continuous technology developments in the advanced driving assistance systems (ADAS). A clear view of the technology developments related to the AVs will give the users insights on the evolution of the technology and predict future research needs. In this paper, firstly, a review is performed on the available ADAS technologies, their functions, and the expected benefits in the context of CVs, AVs, and CAVs such as the sensors deployed on the partial or fully automated vehicles (Radar, LiDAR, etc.), the communication systems for vehicle-to-vehicle and vehicle-to-infrastructure networking, and the adaptive and cooperative adaptive cruise control technology (ACC/CACC). Secondly, for any technologies to be applied in practical AVs related applications, this study also includes a detailed review in the state/federal guidance, legislation, and regulations toward AVs related applications. Last but not least, the impacts of CVs, AVs, and CAVs on traffic are also reviewed to evaluate the potential benefits as the AV related technologies penetrating in the market. Based on the extensive reviews in this paper, the future related research gaps in technology development and impact analysis are also discussed.