Explore the vast range of titles available.

We present a comprehensive multi-messenger study of NGC 1068, the prototype Seyfert II galaxy associated with high-energy neutrinos following a detection by the IceCube Neutrino Observatory. Various aspects of the source, including its nuclear activity, jet, outflow and starburst region, are analysed in detail using a multi-wavelength approach and relevant luminosities are derived. We then explore its γ-ray and neutrino emissions and investigate the potential mechanisms underlying these phenomena and their relations with the different astrophysical components to try to understand which is responsible for the IceCube neutrinos. By first using simple order-of-magnitude arguments and then applying specific theoretical models, we infer that only the region close to the accretion disk around the supermassive black hole has the right density of both the X-ray photons needed to provide the targets for protons to sustain neutrino production and the optical/infrared photons required to absorb the associated, but unobserved, γ-rays. We conclude by highlighting ongoing efforts to constrain a possible broad connection between neutrinos and active galactic nuclei, as well as future synergies between astronomical and neutrino facilities. Observations of the galaxy NGC 1068 in different wavebands are brought together in a multi-messenger case study, exploring the potential origin and mechanisms responsible for the recently detected neutrino emission from this source.

We summarize the radio synchrotron background workshop that took place 2017 July 19-21 at the University of Richmond. This first scientific meeting dedicated to the topic was convened because current measurements of the diffuse radio monopole reveal a surface brightness that is several times higher than can be straightforwardly explained by known Galactic and extragalactic sources and processes, rendering it by far the least well understood photon background at present. It was the conclusion of a majority of the participants that the radio monopole level is at or near that reported by the ARCADE 2 experiment and inferred from several absolutely calibrated zero-level lower frequency radio measurements, and unanimously agreed that the production of this level of surface brightness, if confirmed, represents a major outstanding question in astrophysics. The workshop reached a consensus on the next priorities for investigations of the radio synchrotron background.

Neutral oxygen in the saturnian system shows variability, and the total number of oxygen atoms peaks at 4 x 10³⁴. Saturn's aurora brightens in response to solar-wind forcing, and the auroral spectrum resembles Jupiter's. Phoebe's surface shows variable water-ice content, and the data indicate it originated in the outer solar system. Saturn's rings also show variable water abundance, with the purest ice in the outermost A ring. This radial variation is consistent with initially pure water ice bombarded by meteors, but smaller radial structures may indicate collisional transport and recent renewal events in the past 10⁷ to 10⁸ years.

Solar XUV photons can provide enough energy to account for the observed nitrogen UV dayglow emissions above 800 km, but a small or sporadic contribution from energetic particles cannot be ruled out. Furthermore, ion production at altitudes deeper than 800 km as inferred from radio occultation cannot be produced by solar XUV stimulation and implies energy deposition from protons and oxygen ions. Here we examine UV spectra and visible‐wavelength images of Titan in Saturn's shadow, when XUV stimulation is absent. UV emissions are observed in one of the three sets of spectra, and the intensity of these emissions is about a factor of 10 less than the peak intensity reported on the dayside. We observe visible‐wavelength emissions for the first time. No horizontally resolved auroral structures are seen in the visible images. At visible wavelengths Titan has a global emission at the haze‐top level that is not understood, although cosmic ray ionization and chemiluminescence are candidates needing further investigation. Key Points First definitive observations of Titan airglow from protons or O+ Charged particle precipitation accounts for about 10% of Titan's UV airglow Discovery of airglow at visible wavelengths from within Titan's haze

We summarize the radio synchrotron background workshop that took place 2017 July 19–21 at the University of Richmond. This first scientific meeting dedicated to the topic was convened because current measurements of the diffuse radio monopole reveal a surface brightness that is several times higher than can be straightforwardly explained by known Galactic and extragalactic sources and processes, rendering it by far the least well understood photon background at present. It was the conclusion of a majority of the participants that the radio monopole level is at or near that reported by the ARCADE 2 experiment and inferred from several absolutely calibrated zero-level lower frequency radio measurements, and unanimously agreed that the production of this level of surface brightness, if confirmed, represents a major outstanding question in astrophysics. The workshop reached a consensus on the next priorities for investigations of the radio synchrotron background.

The journey of the Sun through the dynamically active local interstellar medium creates an evolving heliosphere environment. This motion drives a wind of interstellar material through the heliosphere that has been measured with Earth-orbiting and interplanetary spacecraft for 40 years. Recent results obtained by NASA's Interstellar Boundary Explorer mission during 2009-2010 suggest that neutral interstellar atoms flow into the solar system from a different direction than found previously. These prior measurements represent data collected from Ulysses and other spacecraft during 1992-2002 and a variety of older measurements acquired during 1972-1978. Consideration of all data types and their published results and uncertainties, over the three epochs of observations, indicates that the trend for the interstellar flow ecliptic longitude to increase linearly with time is statistically significant.

The Cassini Ultraviolet Imaging Spectrograph (UVIS) observed Titan's dayside limb in the extreme ultraviolet (EUV) and far ultraviolet (FUV) on 22 June 2009 from a mean distance of 23 Titan radii. These high‐quality observations reveal the same EUV and FUV emissions arising from photoelectron excitation and photofragmentation of molecular nitrogen (N2) as found on Earth. We investigate both of these solar driven processes with a terrestrial airglow model adapted to Titan and find that total predicted radiances for the two brightest N2 band systems agree with the observed peak radiances to within 5%. Using N2 densities constrained from in situ observations by the Ion Neutral Mass Spectrometer on Cassini, the altitude of the observed limb peak of the EUV and FUV emission bands is between 840 and 1060 km and generally consistent with model predictions. We find no evidence for carbon emissions in Titan's FUV airglow in contrast to previous Titan airglow studies using UVIS data. In their place, we identify several vibrational bands from the N2 Vegard‐Kaplan system arising from photoelectron impact with predicted peak radiances in agreement with observations. These Titan UV airglow observations are therefore comprised of emissions arising only from solar processes on N2 with no detectable magnetospheric contribution. Weaker EUV Carroll‐Yoshino N2 bands within the v′ = 3, 4, and 6 progressions between 870 and 1020 Å are underpredicted by about a factor of five while the (0,1) band near 980 Å is overpredicted by about a factor of three. Key Points First Cassini UVIS limb observations of Titan Model‐data comparison shows solar forcing alone can explain UV airglow No carbon in Titan's UV airglow, contrary to analysis of other UVIS data

In this paper we present the first nightside EUV and FUV airglow limb spectra of Titan showing molecular emissions. The Cassini Ultraviolet Imaging Spectrograph (UVIS) observed photon emissions of Titan's day and night limb‐airglow and disk‐airglow on multiple occasions, including during an eclipse observation. The 71 airglow observations analyzed in this paper show EUV (600–1150 Å) and FUV (1150–1900 Å) atomic multiplet lines and band emissions arising from either photoelectron induced fluorescence and solar photo‐fragmentation of molecular nitrogen (N2) or excitation by magnetosphere plasma. The altitude of the peak UV emissions on the limb during daylight occurred inside the thermosphere at the altitude of the topside ionosphere (near 1000 km altitude). However, at night on the limb, a subset of emission features, much weaker in intensity, arise in the atmosphere with two different geometries. First, there is a twilight photoelectron‐excited glow that persists with solar depression angle up to 25–30 degrees past the terminator, until the solar XUV shadow height passes the altitude of the topside ionosphere (1000–1200 km). The UV twilight glow spectrum is similar to the dayglow but weaker in intensity. Second, beyond 120° solar zenith angle, when the upper atmosphere of Titan is in total XUV darkness, there is indication of weak and sporadic nightside UV airglow emissions excited by magnetosphere plasma collisions with ambient thermosphere gas, with similar N2 excited features as above in the daylight or twilight glow over an extended altitude range. Key Points First UV nightglow observations of Titan First comparison of dayglow, nightglow, twilight glow and eclipse airglow First study indicating plasma impact excitation of UV airglow

Group A streptococci (GAS) are able to invade cultured epithelial and endothelial cells without evidence of intracellular replication. GAS, like other facultative intracellular bacterial pathogens, evolved such ability to enter and to survive within host cells avoiding the host defences, and bacterial intracellular survival could explain the recurrence of infections. We report here that 1 mg bovine lactoferrin (bLf)/mL significantly hindered the in vitro invasion of cultured epithelial cells by GAS isolated from patients suffering from pharyngitis and completely inhibited the invasiveness of GAS pretreated with subinhibiting concentrations of erythromycin or ampicillin. One milligram of bLf per millilitre was also able to increase the number of epithelial cells undergoing apoptosis following GAS invasion, although the number of intracellular GAS in the presence of bLf decreased by about 10-fold. The ability of bLf to decrease GAS invasion was confirmed by an in vivo trial carried out on 12 children suffering from pharyngitis and already scheduled for tonsillectomy. In tonsil specimens from children treated for 15 days before tonsillectomy with both oral erythromycin (500 mg t.i.d. (three times daily)) and bLf gargles (100 mg t.i.d.), a lower number of intracellular GAS was found in comparison with that retrieved in tonsil specimens from children treated with erythromycin alone (500 mg t.i.d.).Key words: lactoferrin, group A streptococci, invasiveness, anti-invasive activity, apoptosis.