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A search for dark matter particles produced in association with a Higgs boson decaying into a pair of τ leptons is performed using data collected in proton-proton collisions at a center-of-mass energy of 13 TeV with the CMS detector. The analysis is based on a data set corresponding to an integrated luminosity of 101 fb−1 collected in 2017–2018. No significant excess over the expected standard model background is observed. This result is interpreted within the frameworks of the 2HDM+a and baryonic Z′ benchmark simplified models. The 2HDM+a model is a type-II two-Higgs-doublet model featuring a heavy pseudoscalar with an additional light pseudoscalar. Upper limits at 95% confidence level are set on the product of the production cross section and the branching fraction for each of these two simplified models. Heavy pseudoscalar boson masses between 400 and 700 GeV are excluded for a light pseudoscalar mass of 100 GeV. For the baryonic Z′ model, a statistical combination is made with an earlier search based on a data set of 36 fb−1 collected in 2016. In this model, Z′ boson masses up to 1050 GeV are excluded for a dark matter particle mass of 1 GeV.

In people living with HIV (PLWH), surveillance for Leishmania infection is crucial for identify those at risk of developing visceral leishmaniasis (VL). Leishmania -HIV coinfection worsens patient outcomes and increases mortality and relapse rates. We conducted a prospective study (2017–2023) in Northeast Brazil to assess the long-term outcomes of asymptomatic Leishmania -HIV coinfected outpatients and Leishmania- negative PLWH. Participants were drawn from a cross-sectional study performed in 2017, which identified both Leishmania- HIV coinfected and Leishmania- negative PLWH. Epidemiological, clinical, and laboratory data were collected from medical records (2017–2023). In 2023, these individuals were retested for Leishmania using serological tests and conventional polymerase chain reaction (PCR). Categorical variables were compared using the chi-square test, and non-parametric tests were used for quantitative variables. During follow-up, six individuals developed VL: five from the coinfected group and one from the non-coinfected PLWH group (OR 10.4; 95% CI 1.2–94.2; p  = 0.023). Three patients experienced relapse: one from the PLWH group and two from the coinfected group. There was one death in the Leishmania- HIV group. In 2023, 80 patients were retested; five coinfected patients remained positive for VL by one or more tests, and two PLWH patients seroconverted for VL. Our findings underscore the critical need for long-term follow-up of asymptomatic Leishmania -HIV patients to mitigate disease progression and associated complications.