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result(s) for
"Alexander, Nesterov"
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Spacetime as a Complex Network and the Cosmological Constant Problem
2023
We propose a promising model of discrete spacetime based on nonassociative geometry and complex networks. Our approach treats space as a simplicial 3-complex (or complex network), built from “atoms” of spacetime and entangled states forming n-dimensional simplices (n=1,2,3). At large scales, a highly connected network is a coarse, discrete representation of a smooth spacetime. We show that, for high temperatures, the network describes disconnected discrete space. At the Planck temperature, the system experiences phase transition, and for low temperatures, the space becomes a triangulated discrete space. We show that the cosmological constant depends on the Universe’s topology. The “foamy” structure, analogous to Wheeler’s “spacetime foam”, significantly contributes to the effective cosmological constant, which is determined by the Euler characteristic of the Universe.
Journal Article
Primordial Axion Stars and Galaxy Halo Formation
2024
Primordial axion stars, hypothetical stars formed from axions, could play an essential role in forming galaxy halos. These stars could have originated in the early universe shortly after the Big Bang. We show that the ultralight axions forming primordial stars can act as the initial seeds for galaxy halos.
Journal Article
Measuring majority power and veto power of voting rules
2020
We study voting rules with respect to how they allow or limit a majority from dominating minorities: whether a voting rule makes a majority powerful and whether minorities can veto the candidates they do not prefer. For a given voting rule, the minimal share of voters that guarantees a victory to one of the majority’s most preferred candidates is the measure of majority power; and the minimal share of voters that allows the minority to veto each of their least preferred candidates is the measure of veto power. We find tight bounds on such minimal shares for voting rules that are popular in the literature and used in real elections. We order the rules according to majority power and veto power. Instant-runoff voting has both the highest majority power and the highest veto power; plurality rule has the lowest. In general, the greater is the majority power of a voting rule, the greater its veto power. The three exceptions are: voting with proportional veto power, Black’s rule and Borda’s rule, which have relatively weak majority power and strong veto power, thus providing minority protection. Our results can shed light on how voting rules provide different incentives for voter participation and candidate nomination.
Journal Article
Deep Learning for Gravitational-Wave Data Analysis: A Resampling White-Box Approach
by
Nesterov, Alexander I.
,
Morales, Manuel D.
,
Antelis, Javier M.
in
Algorithms
,
binary black holes
,
convolutional neural networks
2021
In this work, we apply Convolutional Neural Networks (CNNs) to detect gravitational wave (GW) signals of compact binary coalescences, using single-interferometer data from real LIGO detectors. Here, we adopted a resampling white-box approach to advance towards a statistical understanding of uncertainties intrinsic to CNNs in GW data analysis. We used Morlet wavelets to convert strain time series to time-frequency images. Moreover, we only worked with data of non-Gaussian noise and hardware injections, removing freedom to set signal-to-noise ratio (SNR) values in GW templates by hand, in order to reproduce more realistic experimental conditions. After hyperparameter adjustments, we found that resampling through repeated k-fold cross-validation smooths the stochasticity of mini-batch stochastic gradient descent present in accuracy perturbations by a factor of 3.6. CNNs are quite precise to detect noise, 0.952 for H1 data and 0.932 for L1 data; but, not sensitive enough to recall GW signals, 0.858 for H1 data and 0.768 for L1 data—although recall values are dependent on expected SNR. Our predictions are transparently understood by exploring tthe distribution of probabilistic scores outputted by the softmax layer, and they are strengthened by a receiving operating characteristic analysis and a paired-sample t-test to compare with a random classifier.
Journal Article
Non-vector-borne transmission of lumpy skin disease virus
by
Yana, Pestova
,
Pavel, Prutnikov
,
Alexander, Sprygin
in
631/1647
,
631/1647/767
,
631/1647/767/1424
2020
The transmission of “lumpy skin disease virus” (LSDV) has prompted intensive research efforts due to the rapid spread and high impact of the disease in recent years, especially in Eastern Europe and Balkan countries. In this study, we experimentally evaluate the vaccine-derived virulent recombinant LSDV strain (Saratov/2017) and provide solid evidence on the capacity of the virus for transmission in a vectorproof environment. In the 60-day long experiment, we used inoculated bulls (IN group) and two groups of in-contact animals (C1 and C2), with the former (C1) being in contact with the inoculated animals at the onset of the trial and the latter (C2) being introduced at day 33 of the experiment. The infection in both groups of contact animals was confirmed clinically, serologically and virologically, and viremia was demonstrated in blood, nasal and ocular excretions, using molecular tools. Further studies into LSDV biology are a priority to gain insights into whether the hypothesized indirect contact mode evidenced in this study is a de novo-created feature, absent from both parental stains of the novel (recombinant) LSDV isolate used, or whether it was dormant, but then unlocked by the process of genetic recombination. Author summary: In global terms, LSD has been termed a “neglected disease” due to its historic natural occurrence of being restricted to Africa and, occasionally, Israel. However, after its slow spread throughout the Middle East, the disease is now experiencing a resurgence of research interest following a recent and rapid spread into more northern latitudes. Given the dearth of solid findings on potential transmission mechanisms, no efficient or reliable control program currently exists, which does not involve the use of live attenuated vaccines or stamping out policies – both of which are controversial for implementation in non-endemic regions or countries. The vector-borne mode is the only working concept currently available, but with scarce evidence to support the aggressive spread northwards – except for human-assisted spread, including legal or illegal animal transportation. The emergence of outbreaks is not consistently linked to weather conditions, with the potential for new outbreaks to occur and spread rapidly. Here, for the first time, we provide evidence for indirect contact-mode transmission for a naturally-occurring recombinant LSDV isolated from the field. In an insect-proof facility, we obtained solid evidence that the novel LSDV strain can pass to in-contact animals. Given the recombinant nature of the virus utilised, its genetic background relating to the observed transmission pattern within the study needs to be delineated.
Journal Article
A Quasigroup Approach for Conservation Laws in Asymptotically Flat Spacetimes
by
Nesterov, Alexander I.
,
Moreno, Claudia
,
Robles, Alfonso Zack
in
Analysis
,
asymptotic structure of spacetime
,
Conservation laws
2025
In the framework of the quasigroup approach to conservation laws in general relativity, we show how the infinite-parametric Newman–Unti group of asymptotic symmetries can be reduced to the Poincaré quasigroup. We compute Noether’s charges associated with any element of the Poincaré quasialgebra. The integral conserved quantities of energy momentum and angular momentum, being linear on generators of the Poincaré quasigroup, are identically equal to zero in Minkowski spacetime. We present a definition of the angular momentum free of the supertranslation ambiguity. We provide an appropriate notion of intrinsic angular momentum and a description of the mass reference frame’s center at future null infinity. Finally, in the center of mass reference frame, the momentum and angular momentum are defined by the Komar expression.
Journal Article
The Combinatorial Fusion Cascade as a Neural Network
The combinatorial fusion cascade provides a surprisingly simple and complete explanation for the origin of the genetic code based on competing protocodes. Although its molecular basis is only beginning to be uncovered, it represents a natural pattern of information generation from initial signals and has potential applications in designing more-efficient neural networks. By utilizing the properties of the combinatorial fusion cascade, we demonstrate its embedding into deep neural networks with sequential fully connected layers using the dynamic matrix method and compare the resulting modifications. We observe that the Fiedler Laplacian eigenvector of a combinatorial cascade neural network does not reflect the cascade architecture. Instead, eigenvectors associated with the cascade structure exhibit higher Laplacian eigenvalues and are distributed widely across the network. We analyze a text classification model consisting of two sequential transformer layers with an embedded cascade architecture. The cascade shows a significant influence on the classifier’s performance, particularly when trained on a reduced dataset (approximately 3% of the original). The properties of the combinatorial fusion cascade are further examined for their application in training neural networks without relying on traditional error backpropagation.
Journal Article
Efficient lottery design
by
Kesten, Onur
,
Nesterov, Alexander S.
,
Kurino, Morimitsu
in
Algorithms
,
Assignment problem
,
Decomposition
2017
There has been a surge of interest in stochastic assignment mechanisms that have proven to be theoretically compelling thanks to their prominent welfare properties. Contrary to stochastic mechanisms, however, lottery mechanisms are commonly used in real life for indivisible goods allocation. To help facilitate the design of practical lottery mechanisms, we provide new tools for obtaining stochastic improvements in lotteries. As applications, we propose lottery mechanisms that improve upon the widely used random serial dictatorship mechanism and a lottery representation of its competitor, the probabilistic serial mechanism. The tools we provide here can be useful in developing welfare-enhanced new lottery mechanisms for practical applications such as school choice.
Journal Article
The Combinatorial Fusion Cascade to Generate the Standard Genetic Code
2021
Combinatorial fusion cascade was proposed as a transition stage between prebiotic chemistry and early forms of life. The combinatorial fusion cascade consists of three stages: eight initial complimentary pairs of amino acids, four protocodes, and the standard genetic code. The initial complimentary pairs and the protocodes are divided into dominant and recessive entities. The transitions between these stages obey the same combinatorial fusion rules for all amino acids. The combinatorial fusion cascade mathematically describes the codon assignments in the standard genetic code. It explains the availability of amino acids with the even and odd numbers of codons, the appearance of stop codons, inclusion of novel canonical amino acids, exceptional high numbers of codons for amino acids arginine, leucine, and serine, and the temporal order of amino acid inclusion into the genetic code. The temporal order of amino acids within the cascade is congruent with the consensus temporal order previously derived from the similarities between the available hypotheses. The control over the combinatorial fusion cascades would open the road for a novel technology to develop artificial microorganisms.
Journal Article
A recombinant vaccine-like strain of lumpy skin disease virus causes low-level infection of cattle through virus-inoculated feed
2022
Since 1989, lumpy skin disease of cattle (LSD) has spread out of Africa via the Middle East northwards and eastwards into Russia, the Far East and South-East Asia. It is now threatening to become a worldwide pandemic, with Australia possibly next in its path. One of the research gaps on the disease concerns its main mode of transmission, most likely via flying insect vectors such as biting flies or mosquitoes. Direct or indirect contact transmission is possible, but appears to be an inefficient route, although there is evidence to support the direct contact route for the newly detected recombinant strains first isolated in Russia. In this study, we used experimental bulls and fed them via virus-inoculated feed to evaluate the indirect contact route. To provide deeper insights, we ran two parallel experiments using the same design to discover differences that involved classical field strain Dagestan/2015 LSDV and recombinant vaccine-like Saratov/2017. Following the attempted indirect contact transmission of the virus from the inoculated feed via the alimentary canal, all bulls in the Dagestan/2015 group remained healthy and did not seroconvert by the end of the experiment, whereas for those in the Saratov/2017 recombinant virus group, of the five bulls fed on virus-inoculated feed, three remained clinically healthy, while two displayed evidence of a mild infection. These results provide support for recombinant virus transmission via the alimentary canal. In addition, of particular note, the negative control in-contact bull in this group exhibited a biphasic fever at days 10 and 20, developed lesions from day 13 onwards, and seroconverted by day 31. Two explanations are feasible here: one is the in-contact animal was somehow able to feed on some of the virus-inoculated bread left over from adjacent animals, but in the case here of the individual troughs being used, that was not likely; the other is the virus was transmitted from the virus-fed animals via an airborne route. Across the infected animals, the virus was detectable in blood from days 18 to 29 and in nasal discharge from days 20 to 42. Post-mortem and histological examinations were also indicative of LSDV infection, supporting further evidence for rapid, in F transmission of this virus. This is the first report of recombinant LSDV strain transmitting via the alimentary mode.
Journal Article