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This study aimed to investigate the effectiveness of counseling and logotherapy on reducing the psychological depression among a sample of (30) kidney patients aged (45-58) years, who were non-randomly selected from those have high psychological depression after implementing the beck depression Inventory (BDI) on them. Patients were divided into two groups, one experimental group that consists of (15) patients who have been exposed to a counseling and therapeutic program using counseling and logotherapy, and a controlled group that consists of (15) patients who did not receive any counseling program. The study used the psychological depression scale and the logotherapy counseling program, according to the existential psychotherapy theory. The study results found effectiveness of counseling and logotherapy on reducing the psychological depression among kidney patients in the experimental group, and the continuity of program effectiveness after one month of follow-up.