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result(s) for
"Anchan, Chetan"
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Pediatric extremity rhabdomyosarcoma treated with re-brachytherapy in recurrent setting
by
Kapoor, Ankita Rungta
,
Bakshi, Chetna
,
Anchan, Chetan
in
Care and treatment
,
Case Report
,
Case reports
2022
Rhabdomyosarcomas (RMS) are pediatric soft-tissue sarcomas arising from immature mesenchymal cells that are intended to form striated skeletal muscles. Brachytherapy delivers high-dose of precised radiation to the target tissue with high conformity, sparing the nearby normal tissues, hence allowing dose escalation and reducing the likelihood of normal tissue toxicity. There is a scarcity of reports on the use of brachytherapy for extremity RMS. We report the case of pediatric extremity RMS treated with re-brachytherapy in recurrent setting. A 4-year-old boy diagnosed with RMS of right upper arm underwent local excision of the lesion. Postoperative magnetic resonance imaging showed suspicious residual lesion. Revision surgery followed by brachytherapy with 30 Gy in 10 fractions twice a day over 5 days was delivered. The child developed local recurrence after 12 months. Reexcision and re-irradiation with brachytherapy were done delivering 27 Gy in 9 fractions twice a day over 5 days. The child is disease-free 18 months posttreatment with no significant disparity in limb length suggestive of successful preservation of growth epiphysis. Re-irradiation with interstitial brachytherapy can be considered as an option for the treatment of recurrent pediatric extremity rhabdomyosarcoma, in conjunction with surgery and chemotherapy, despite treated previously with brachytherapy.
Journal Article
Pediatric extremity rhabdomyosarcoma treated with re-brachytherapy in recurrent setting
by
Kapoor, Ankita Rungta
,
Bakshi, Chetna
,
Anchan, Chetan
in
Care and treatment
,
Pediatric research
,
Physiological aspects
2022
Rhabdomyosarcomas (RMS) are pediatric soft-tissue sarcomas arising from immature mesenchymal cells that are intended to form striated skeletal muscles. Brachytherapy delivers high-dose of precised radiation to the target tissue with high conformity, sparing the nearby normal tissues, hence allowing dose escalation and reducing the likelihood of normal tissue toxicity. There is a scarcity of reports on the use of brachytherapy for extremity RMS. We report the case of pediatric extremity RMS treated with re-brachytherapy in recurrent setting. A 4-year-old boy diagnosed with RMS of right upper arm underwent local excision of the lesion. Postoperative magnetic resonance imaging showed suspicious residual lesion. Revision surgery followed by brachytherapy with 30 Gy in 10 fractions twice a day over 5 days was delivered. The child developed local recurrence after 12 months. Reexcision and re-irradiation with brachytherapy were done delivering 27 Gy in 9 fractions twice a day over 5 days. The child is disease-free 18 months posttreatment with no significant disparity in limb length suggestive of successful preservation of growth epiphysis. Re-irradiation with interstitial brachytherapy can be considered as an option for the treatment of recurrent pediatric extremity rhabdomyosarcoma, in conjunction with surgery and chemotherapy, despite treated previously with brachytherapy.
Journal Article
Giant cell tumor of bone with secondary aneurysmal bone cyst
2008
Though its name may imply that the characteristic large osteoclastic giant cells of a GCT of bone are responsible for the proliferative capacity of the tumor, there is evidence that the stromal-like cells which are the major component of the mononuclear cell population represent the true neoplastic component of the tumor. [3] Aneurysmal bone cyst (ABC) is a benign cystic lesion of bone that is composed of blood-filled spaces separated by connective tissue septa containing fibroblasts, osteoclast-type giant cells, and reactive woven bone.
Journal Article
Recurrent gossypiboma in the thigh
by
Anchan, Chetan
,
Jambhekar, Nirmala A.
,
Agarwal, Manish G.
in
Biological and medical sciences
,
Biopsy
,
Dermatology
2007
Gossypiboma, an iatrogenic mass lesion caused by a retained surgical sponge is an extremely rare event following musculoskeletal procedures. This entity is therefore a very unusual experience and can create considerable confusion. Unsuspecting surgeons may thus be caught out by this unlikely presentation. We present our experience with a recurrent gossypiboma in the thigh occurring several years after surgical evacuation of a similar gossypiboma from the same anatomic location with interval resolution of symptoms. The purpose of this case report is to highlight the possibility of a \"recurrent\" soft tissue mass occurring for reasons other than a neoplasm. In the absence of a definitive biopsy diagnosis of tumor in patients who have undergone prior surgical procedures in that area, it may be more prudent to adopt a conservative surgical resection rather than a conventional radical resection as warranted by the dramatic clinical presentation mimicking a soft tissue sarcoma.
Journal Article