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To estimate: (1) how much time half- and full-siblings are exposed to each other during childhood and adolescence; (2) how half-sibling exposure is conditional on birth spacing and residency; and (3) how parents' social vulnerability is associated with different levels of lifetime exposure to half-siblings. Swedish register data is used to calculate exposure to half-siblings based on birth spacing and registered residency for all full- and half-siblings in the 1994 birth cohort. A substantive share of half-siblings are less exposed to each other due to lengthy birth spacing and residency patterns. By age 18, 26% of the birth cohort have had a half-sibling who is also no older than 18 for at least one year; 13% of the birth cohort have had a half-sibling who is no older than 18 for up to 10 years; 8% of the birth cohort have been registered in the same dwelling as another half-sibling for eight years or more. Parents' social vulnerability does not predict exposure to halfsiblings among the population that has at least one half-sibling by age 18. Even though half-siblings constitute a large share of all siblings, full-siblings will likely make up the vast majority of the siblingship-like relationships because so many halfsiblings are unable to interact during childhood or adolescence due to extensive age differences and/or because they do not coreside.

BACKGROUND The decline in marriage and increases in cohabiting unions during childbearing ages represent a major change in family structures and family dynamics. Yet no comprehensive description has covered period trends in the prevalence of marital and nonmarital unions or partnership entry and exit rates across educational levels. OBJECTIVE We describe period trends in the proportion of individuals in union and the flow of union formation and dissolution at ages 18-49 across educational levels for men and women in 1989-2019 in Finland. METHODS We use register data with full histories of coresidential unions regardless of marital status. We calculate the age-specific yearly prevalence of marriages, cohabitations, and all coresidential unions, and rates of union formation and separation. RESULTS The prevalence of marriage declined across educational groups. Increases in the prevalence of nonmarital cohabitation are slightly smaller than declines in marriage; as a result, the total union prevalence declined, especially among low-educated men and women. Union formation rates have declined since around 2010, and separation rates have increased notably, especially among the lower educated and in age groups below 35. CONCLUSIONS The increase in nonmarital cohabitation has not fully covered the decline in the stock of marriages. The increases in union instability are notable. All observed trends and educational gradients are remarkably similar among men and women. CONTRIBUTION We provide the first comprehensive population-level estimates of trends and patterns of the union stock and the flow of marital and nonmarital unions by education for both men and women of childbearing ages.

IntroductionThere are great potential benefits of being able to conduct neuropsychological assessments remotely, especially for hard-to-reach or less mobile patient groups. Such tools need to be equivalent to standard tests done in the clinic and also easy to use in a variety of clinical populations.Methods and analysisThis study protocol describes a cross-sectional study aimed at validating the newly developed digitalized neuropsychological test battery Mindmore Remote in patients with neurological disorders and injuries. Diagnoses comprise traumatic brain injury, stroke, Parkinson’s disease, multiple sclerosis, brain tumour and epilepsy. 50 patients in each patient group will be included. In addition, 50 healthy controls will be recruited. All participants will undergo both testing with Mindmore Remote at home and traditional neuropsychological assessment face-to-face in a randomised order. The primary outcome is the association between tests from the Mindmore Remote battery and their equivalent traditional neuropsychological tests. Further, bias between methods and differences between groups will also be investigated.Ethics and disseminationThe study protocol has been approved by the Swedish Ethical Review Authority (2022-06230-01) and adheres to the declaration of Helsinki. All participants will be given oral and written information about the study and sign informed consent forms before entering the study. All participants are informed that they can terminate their participation in the study at any given time, without giving any explanation, and participating in the study or not will not affect their care at the clinic. Neither authors nor personnel involved in the research project are affiliated with Mindmore AB. The results from the study will be published in peer-reviewed scientific journals and presented at national and international conferences on the topic.Trial registration numberNCT05819008.

There is a need for better understanding of various characteristics in hyperacusis in the general population. The objectives of the present study were to investigate individuals in the general population with hyperacusis regarding demographics, lifestyle, perceived general health and hearing ability, hyperacusis-specific characteristics and behavior, and comorbidity. Using data from a large-scale population-based questionnaire study, we investigated individuals with physician-diagnosed (n = 66) and self-reported (n = 313) hyperacusis in comparison to individuals without hyperacusis (n = 2995). High age, female sex, and high education were associated with hyperacusis, and that trying to avoid sound sources, being able to affect the sound environment, and having sough medical attention were common reactions and behaviors. Posttraumatic stress disorder, chronic fatigue syndrome, generalized anxiety disorder, depression, exhaustion, fibromyalgia, irritable bowel syndrome, migraine, hearing impairment, tinnitus, and back/joint/muscle disorders were comorbid with hyperacusis. The results provide ground for future study of these characteristic features being risk factors for development of hyperacusis and/or consequences of hyperacusis.

Multiple chemical sensitivity (MCS) is characterized by widespread symptoms attributed to exposure to airborne chemicals. MCS is categorized as a functional somatic syndrome (FSS), and MCS cases often meet the criteria for other types of FSS, e.g. fibromyalgia. The primary aim was to characterize MCS regarding symptom triggers, symptoms, lifestyle and describe demographics, socioeconomics and lifestyle factors associated with MCS. A secondary aim was to examine the implication of FSS comorbidity. Data were derived from a random sample of the Danish adult population enrolled in the Danish Study of Functional Disorders (DanFunD; n = 9,656). Questionnaire data comprised information used to delimit MCS and four additional types of FSS, as well as data on demographics, socioeconomics and lifestyle. MCS cases (n = 188) was stratified into subgroups; MCS only (n = 109) and MCS with comorbid FSS (n = 73). Information regarding FSS comorbidities were missing for six MCS cases. MCS subgroups and controls without FSS comorbidities (n = 7,791) were compared by means of logistic regression analyses, adjusted for age and sex. MCS was associated with female sex, not being in occupation and low social status, but not with age or education. MCS cases reported normal dietary intake and smoking habits and lower alcohol consumption. Additional associations were found between MCS and low rate of cohabitation, sedentarism, daily physically limitations, and poor quality of sleep. However, subgroup analysis revealed that these findings were primarily associated with MCS with comorbid FSS. MCS was associated with lower socioeconomic status, physically inactivity and poor quality of sleep. Subgroup analysis revealed that several associations was explained by FSS comorbidity, i.e. MCS cases with no comorbid FSS showed normal rate of cohabitation and did not report physical limitations or difficulties sleeping. Overall, our findings emphasise the importance of screening MCS cases for FSS comorbidity both in epidemiological and clinical settings.

This article presents results from a study of online presence in activist milieus associated with the radical left in Sweden discussed from a perspective of non-participation. With the aim to further the understanding of digital non-participation as communicative strategy in activism, it builds upon empirical findings and argues that the online practices and use of social media, as could be observed in milieus associated with the radical left, indicates active non-participation and that this, in turn, is related to the ambition to claim autonomy. The article draws from existing scholarship on critical perspectives on protest movements and social media as well as empirical examples of online content published by radical leftist groups. Furthermore, it analyses how these activities could be understood in terms of active and passive non-participation, abstention or adaptation to social media affordances, as well as implosion of the social in digital media. The findings suggest that much of the activities in the material could be described as active non-participation and that this media practice relates to ideological positioning and values in the milieu.

The evidence for differences between women and men in terms of olfactory abilities is contradictory. We analyzed women and men’s performance and reactions to a wider range of odour exposure outcomes than usually studied, to assess possible differences and similarities between sexes. Measures of sensitivity and sensory decision rule were established in 37 women and 39 men. Perceptual, cognitive, symptom-related and autonomic nervous system (skin conductance level and heart-rate variability) reactions were also assessed during extended ambient odour exposure, as well as participants’ self-rated chemical intolerance. Bayesian analyses consistently revealed greater support for sex-related similarities than differences, suggesting that women and men perform and react comparably not only in terms of basic olfactory measures, but also to environmental odour exposure mimicking everyday situations.

Monitoring the use of antimicrobials and the emergence of resistance in animals and people is important for the control of antimicrobial resistance, and for establishing sustainable and effective disease management practices. In this study, we used Enterococcus spp. and Escherichia coli as indicator species to investigate antimicrobial susceptibility patterns and how these change over time, on ten Swedish pig farms. Indoor environmental sock sampling was performed once a month during the entire production cycle of one batch of pigs on each farm, resulting in 60 samples collected in total. Selective culture for E. coli and Enterococcus spp. resulted in 122 isolates of E. coli , 74 isolates of E. faecium , but no isolates of E. faecalis . Microdilution was used to determine minimum inhibitory concentrations for twelve antimicrobial substances in E. coli and fifteen substances in E. faecium . The overall prevalence of resistance was low. Among the E. coli isolates, the proportions non-wild type (resistant, NWT) isolates were as follows: azithromycin and amikacin 1% (n = 1), trimethoprim and sulfamethoxazole 2% (n = 3), ampicillin 6% (n = 7) and tetracycline 9% (n = 11). Among the E. faecium isolates, the NWT proportions were: teicoplanin, linezolid and gentamicin 1% (n = 1), daptomycin 3% (n = 2), erythromycin 26% (n = 19), tetracycline 27% (n = 20), quinupristin/dalfopristin 58% (n = 42). The resistance patterns differed between the farms, likely due to different antimicrobial use, biosecurity measures and source of the animals. The NWT prevalence among E. coli decreased over time, whereas no similar trend could be observed in E. faecium . The results of the current study illustrate the complex factors affecting the antimicrobial resistance patterns observed on each farm, indicating that specific practices and risk factors have an impact on the prevalence and type of antimicrobial resistance. Further studies of the farm environments in combination with antimicrobial use and other risk factor data are needed to elucidate the multifaceted drivers of antimicrobial resistance development on livestock farms.

Background Olfactory dysfunction together with neurological and cognitive symptoms are common after COVID‐19. We aimed to study whether performance on olfactory and neuropsychological tests following infection predict post‐COVID condition (PCC), persisting symptoms, and reduced health‐related quality of life. Methods Both hospitalized (N = 10) and non‐hospitalized individuals (N = 56) were enrolled in this prospective cohort study. Participants were evaluated 1–3 months after infection with an olfactory threshold test and neuropsychological tests, which was used as predictors of PCC. A questionnaire outlining persisting symptoms and the validated instrument EuroQol five‐dimension five‐level for health‐related quality of life assessment were used as outcome data 1 year after infection (N = 59). Principal component analysis was used to identify relevant predictors for PCC at 1 year. Results Objectively assessed olfactory dysfunction at 1–3 months post infection, but not subjective olfactory symptoms, predicted post‐COVID condition with reduced health‐related quality of life (PCC+) at 1 year. The PCC+ group scored more often below the cut off for mild cognitive impairment on the Montreal Cognitive Assessment (61.5% vs. 21.7%) and higher on the Multidimensional Fatigue Inventory‐20, compared to the group without PCC+. Conclusion Our results indicate that objectively assessed, olfactory dysfunction is a predictor for PCC+. These findings underscore the importance of objective olfactory testing. We propose that olfactory screening in the early post‐acute phase of COVID‐19 infection might identify individuals that are at higher risk of developing long‐term health sequalae. Objectively assessed olfactory dysfunction at one to three months after COVID‐19, but not subjective olfactory symptoms, predicted post‐COVID condition (PCC) at one year. We propose that olfactory screening in the early post‐acute phase of COVID‐19 infection might identify individuals that are at higher risk of developing long‐term health sequalae.