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"Andrei, Alexandre"
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Endophytic Species of the Genus Colletotrichum as a Source of Bioactive Metabolites: A Review of Their Biotechnological Potential
by
da Silva, Manuela Vitoria Nascimento
,
Alexandre, Andrei da Silva
,
Nunez, Cecilia Veronica
in
Anthracnose
,
Antibacterial agents
,
Antifungal agents
2025
The genus Colletotrichum is widely known for its phytopathological significance, especially as the causative agent of anthracnose in diverse agricultural crops. However, recent studies have unveiled its ecological versatility and biotechnological potential, particularly among endophytic species. These fungi, which asymptomatically colonize plant tissues, stand out as high-yielding producers of bioactive secondary metabolites. Given their scientific and economic relevance, this review critically examines endophytic Colletotrichum species, focusing on the chemical diversity and biological activities of the metabolites they produce, including antibacterial, antifungal, and cytotoxic activity against cancer cells, and antioxidant properties. This integrative review was conducted through a structured search of scientific databases, from which 39 relevant studies were selected, highlighting the chemical and functional diversity of these compounds. The analyzed literature emphasizes their potential applications in pharmaceutical, agricultural, and industrial sectors. Collectively, these findings reinforce the promising biotechnological potential of Colletotrichum endophytes not only as sources of bioactive metabolites but also as agents involved in ecological regulation, plant health promotion, and sustainable production systems.
Journal Article
5,6-Dihydro-5,6-Epoxymultiplolide A, Cytosporone C, and Uridine Production by Diaporthe hongkongensis, an Endophytic Fungus from Minquartia guianensis
by
Silva, David Ribeiro da
,
Nunez, Cecilia Veronica
,
Casas, Luana Lopes
in
Agricultural land
,
Antifungal agents
,
Biodiversity
2025
Endophytic fungi are valuable sources of bioactive secondary metabolites, with potential applications in pharmaceutical and agricultural fields. This study investigates the metabolic potential of Diaporthe hongkongensis, an endophytic fungus isolated from Minquartia guianensis. To date, no secondary metabolites have been identified from this species, highlighting the novelty of this research and its contribution to understanding the chemical diversity of endophytic fungi. The fungus was cultivated on parboiled rice under static and dark conditions for 28 days, leading to the isolation of the following three compounds: 5,6-dihydro-5,6-epoxymultiplolide A (1), cytosporone C (2), and uridine (3). Structural identification was carried out using nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry. The results revealed the metabolic versatility of D. hongkongensis, as demonstrated by its ability to produce structurally diverse substances with biological relevance. Hence, it describes the first isolation of secondary metabolites from the endophytic fungus D. hongkongensis, marking a significant step in understanding its chemical profile. The identification of a known antifungal compound and a lactone derivative underscores the biosynthetic potential of this endophytic fungus, while the isolation of a nucleoside expands the chemical repertoire of fungal metabolites, suggesting possible roles in cellular metabolism and stress adaptation. These findings highlight the role of endophytic fungi as prolific sources of structurally diverse and potentially bioactive natural products, supporting further exploration of their biotechnological applications.
Journal Article
DIVISION I: COMMISSION 8: ASTROMETRY
2013
The business meeting was opened by the President, Dafydd Evans, who presented the agenda, which was approved. It was agreed that Norbert Zacharias should be the secretary of the meeting and take the minutes. This session was attended by about 20 participants.
Journal Article
The parsec program: a large sample of brown dwarf trigonometric parallaxes
by
Bucciarelli, Beatrice
,
Penna, Jucira L.
,
Crosta, Mariateresa
in
Contributed Papers
,
Dwarf stars
,
Trigonometry
2012
We report on the parsec program, which observed 140 L and T dwarfs on a regular basis from 2007 to 2011, using the WIFI camera on the ESO/2.2 m telescope. Trigonometric parallaxes at 5 mas precision are derived for 49 objects, and mas yr−1-level proper motions are derived for approximately 200,000 objects in the same fields. We discuss image cleaning, object centroiding, and astrometric methods, in particular three different approaches for trigonometric parallax determination.
Journal Article
The luminosity function of quasars by the Principle of Maximum Entropy
by
Guedes, Leandro L S
,
Coelho, Bruno
,
Alexandre, Andrei
in
Data points
,
Luminosity
,
Maximum entropy
2019
We propose a different way to obtain the distribution of the luminosity function of quasars by using the Principle of Maximum Entropy. The input data comes from the SDSS-DR3 quasars counts, extending up to redshift 5 and limited from apparent magnitude \\(i=15\\) to 19.1 at \\(z3\\) to \\(i=20.2\\) for \\(z3\\). Using only few initial data points, the Principle allows us to estimate probabilities and hence that luminosity curve. We carry out statistical tests to evaluate our results. The resulting luminosity function compares well to earlier determinations. And our results remain consistent either when the amount or choice of sampled sources is unbiasedly altered. Besides this we estimate the distribution of the luminosity function for redshifts in which there is only observational data in the vicinity.
Development and first year of results from the Heliometer of Observatório Nacional
by
Oliveira, Luiz C.
,
Penna, Jucira L.
,
Coletti, Alissandro
in
Astronomy
,
Climate change
,
Contributed Papers
2012
Recent research on global climate changes points to three distinct sources of climate disturbance: anthropogenic; natural changes in the oceans and atmosphere; and irregularities in the solar cycles. One of the most direct ways to survey an exogenous component of the climatic variability is through the measurement of variations in the diameter and shape of the solar disk. At Observatório Nacional/MCTI, Rio de Janeiro, after several years of diameter observation using a CCD Solar Astrolabe, these measurements are now performed by a state-of-the-art Solar Heliometer. The heliometric method is one of the most successful techniques to measure small variations of angles. Its principle has been used for the latest space borne astrometric missions, aiming to milli-arcsecond precision. The success of this method relies in the fact that it minimizes the dependence of angular measurements to the thermal and mechanical stability of the instrument. However in the classic heliometer the objective is split into two halves to which is applied a linear displacement along the cut, thus still leaving room for a residual dependence with the focus, due to non-concentricity of the beams of the two images. The focus variation, as well as the effects brought by the large temperature variations during solar observations, was tackled in the Solar Heliometer by having all optical elements and their niches made on CCZ, and the telescope tube on carbon fiber, both materials of negligible thermal coefficient. Additionally, the measures are made perpendicular to the separation direction and the plate scale can be known at every time from the solar motion itself. We present the results from the first year of measurements, in special exploring the upheaval of solar activity on late 2011.
Journal Article
Remarks of Gaia DR1 magnitude using ground-based optical monitoring of QSOs
by
Taris, François
,
Damljanović, Goran
,
Andrei, Alexandre
in
Astronomy
,
Contributed Papers
,
Cyclotron frequency
2017
Since September 2016, the first release (DR1) of the Gaia catalogue was appeared. The optical Gaia positions of sources will be linked to the ICRF (VLBI radio positions of mostly quasars, QSOs). For high accurate link we need to investigate variations of optical flux of QSOs via their magnitude variations using data of ground-based telescopes. To do that, from 2013 we observed 47 QSOs and other sources; nine optical telescopes were used for that monitoring. To increase the total number of objects for the link, after a first set of 70 objects (Bourda et al. 2008), Bourda et al. (2011) established a second set of 47 objects. It is necessary to investigate the photometry and morphology of these objects. We collected ground-based data of QSOs (B, V and R mag) and compared with G mag of Gaia DR1; some results are presented here.
Journal Article
COMMISSION 8: ASTROMETRY
2008
Van Leeuwen has completed and published the new reduction of the Hipparcos data. Parallax accuracies have improved by up to a factor five for the brightest stars and correlations effectively removed. [PUBLICATION ABSTRACT]
Journal Article
High precision astrometry mission for the detection and characterization of nearby habitable planetary systems with the Nearby Earth Astrometric Telescope (NEAT)
2012
A complete census of planetary systems around a volume-limited sample of solar-type stars (FGK dwarfs) in the Solar neighborhood (d ≤ 15 pc) with uniform sensitivity down to Earth-mass planets within their Habitable Zones out to several AUs would be a major milestone in extrasolar planets astrophysics. This fundamental goal can be achieved with a mission concept such as NEAT—the Nearby Earth Astrometric Telescope. NEAT is designed to carry out space-borne extremely-high-precision astrometric measurements at the 0.05 μas (1 σ) accuracy level, sufficient to detect dynamical effects due to orbiting planets of mass even lower than Earth’s around the nearest stars. Such a survey mission would provide the actual planetary masses and the full orbital geometry for all the components of the detected planetary systems down to the Earth-mass limit. The NEAT performance limits can be achieved by carrying out differential astrometry between the targets and a set of suitable reference stars in the field. The NEAT instrument design consists of an off-axis parabola single-mirror telescope (D = 1 m), a detector with a large field of view located 40 m away from the telescope and made of 8 small movable CCDs located around a fixed central CCD, and an interferometric calibration system monitoring dynamical Young’s fringes originating from metrology fibers located at the primary mirror. The mission profile is driven by the fact that the two main modules of the payload, the telescope and the focal plane, must be located 40 m away leading to the choice of a formation flying option as the reference mission, and of a deployable boom option as an alternative choice. The proposed mission architecture relies on the use of two satellites, of about 700 kg each, operating at L2 for 5 years, flying in formation and offering a capability of more than 20,000 reconfigurations. The two satellites will be launched in a stacked configuration using a Soyuz ST launch vehicle. The NEAT primary science program will encompass an astrometric survey of our 200 closest F-, G- and K-type stellar neighbors, with an average of 50 visits each distributed over the nominal mission duration. The main survey operation will use approximately 70% of the mission lifetime. The remaining 30% of NEAT observing time might be allocated, for example, to improve the characterization of the architecture of selected planetary systems around nearby targets of specific interest (low-mass stars, young stars, etc.) discovered by Gaia, ground-based high-precision radial-velocity surveys, and other programs. With its exquisite, surgical astrometric precision, NEAT holds the promise to provide the first thorough census for Earth-mass planets around stars in the immediate vicinity of our Sun.
Journal Article
DIVISION I / WORKING GROUP NOMENCLATURE FOR FUNDAMENTAL ASTRONOMY
by
Kumkova, Irina I.
,
Kovalevsky, Jean
,
Fukushima, Toshio
in
Astronomy
,
Contributed Papers
,
Nomenclatures
2007
The IAU Division I Working Group on Nomenclature for Fundamental Astronomy (NFA) was established by the IAU XXV General Assembly with the task of providing proposals for new nomenclature associated with the implementation of the IAU XXIV GA resolutions (2000) and to make related educational efforts for bringing the issue to the notice of scientists in the community.
Journal Article