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"Ascatigno, Leonardo"
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The World Café as a Tool for Evaluating the Level of Acceptance of SARS‐CoV‐2 Screening in School Settings, Puglia Region, Italy, 2023
by
Gabrielli, Elisa
,
Nuccetelli, Fabiana
,
Lopalco, Pier Luigi
in
Acceptance
,
Adolescent
,
Adolescents
2025
Background The introduction of screening tests for Sars‐CoV‐2 has been an extraordinary prevention and control tool during the COVID‐19 pandemic. However, pandemic control interventions, including screening and vaccine mandates, induced refusal reactions in many people. To date, little information is available on the levels of acceptance of screening practices by the young population in school settings. Objective The objective of this work is to survey students' attitudes, behaviours and emotions towards Covid‐19 screening tests by the means of a participatory research method, the World Café (WC). Materials and Methods Between March and May 2023, three WC sessions were conducted in three high schools, with 70 students enrolled on a voluntary basis. As per standard procedure, a moderator was assigned at each table to facilitate dialogue and the WCs were recorded, transcribed and imported into ATLAS.ti software for qualitative analysis. Results The analysis showed that the themes most reported during the WCs were those regarding the emotional domain, particularly feelings of distress, anxiety, fear, frustration, inadequacy and loneliness. Discussion Although the themes ‘Emotions/thoughts’ appear to be the most prominent among students, also ‘Public health policies’ constitutes a predominant theme group. Finally, the theme ‘Communication’ sparked lively debate, being the fourth most discussed topic. Conclusions The many insights from the WC analysis, when properly reframed, bring out useful elements for taking actions during prevention campaigns. Institutions and schools should focus on disseminating clear and targeted messages to help fight misinformation and distrust. Moreover, such evidence suggests that the World Café method proves to be useful and effective for exploring the emotional sphere of adolescents and analysing their thoughts, attitudes and knowledge. Patient or Public Contribution The research team collaborated with the school personnel to set up the right setting for running the World Café sessions. The World Café method allowed the researchers to gather students' insights by the means of a participative process. Honest debate and active engagement of students provided the researchers with a list of statements very useful for informing health policy and recommendations.
Journal Article
Self-reported olfactory and gustatory dysfunctions in COVID-19 patients: a 1-year follow-up study in Foggia district, Italy
by
Lopalco, Pier Luigi
,
Fortunato, Francesca
,
Ascatigno, Leonardo
in
Age groups
,
Ageusia
,
Anosmia
2022
Background
From the initial stages of the pandemic in early 2020, COVID-19-related olfactory and gustatory dysfunctions have been widely reported and are emerging as one of the most frequent long-term sequelae of SARS-CoV-2 infection. However, data regarding the long-term recovery of the sense of smell and taste are lacking. This study aimed to characterize the evolution up to one year after the diagnosis of self-reported olfactory and gustatory dysfunctions in COVID-19 cases.
Methods
Based on the data of the active surveillance platform of the Apulia region, Italy, we selected the residents of Foggia district who were confirmed positive for SARS-CoV-2 from March 1st to June 16th, 2020, and home-quarantined with paucisymptomatic-to-mild clinical presentation. Self-reported olfactory and gustatory dysfunctions were recorded at baseline through a survey of dichotomous questions. The evolution of these symptoms at approximately one year was prospectively assessed via telephone by the validated sino-nasal outcome test 22 (SNOT-22, Italian version).
Results
Among the 1,175 COVID-19 cases notified in the Foggia district during the first epidemic wave, 488 had paucisymptomatic-to-mild clinical presentation. Of these, 41.2% (n = 201, 95% confidence interval [CI] 36.8–45.7%) reported at least one sensory dysfunction. A total of 178 to 201 (88.5%) patients agreed to participate in the follow-up survey. According to the SNOT-22 results, the persistence of a sensory dysfunction was observed in the 29.8% (n = 53, 95% CI 23.2–37.1%) of them. Particularly, loss of smell persisted in 25.8% (n = 46, 95% CI 19.6–32.9%), loss of taste in 21.3% (n = 38, 95% CI 15.6–28.1%), loss of both in 17.4% (n = 31, 95% CI 12.2–23.8%) of participants in the follow-up. The rates of full recovery increased over time: from 59% at 30 days to 71.9% at 90 days for the sense of smell; from 61.3% at 30 days to 74.7% at 90 days for the sense of taste.
Conclusions
The persistence of COVID-19-related olfactory and gustatory dysfunctions up to 12 months after the disease onset in a noteworthy proportion (approximately 3 out of 10) of patients with paucisymptomatic-to-mild clinical presentation deserves further investigations due to its possible pathophysiological implications and impact on the quality of life.
Journal Article
Association of socio-economic deprivation with COVID-19 incidence and fatality during the first wave of the pandemic in Italy: lessons learned from a local register-based study
by
Lopalco, Pier Luigi
,
Fortunato, Francesca
,
Ascatigno, Leonardo
in
Adolescent
,
Adult
,
Care and treatment
2023
Background
COVID-19 has been characterised by its global and rapid spread, with high infection, hospitalisation, and mortality rates worldwide. However, the course of the pandemic showed differences in chronology and intensity in different geographical areas and countries, probably due to a multitude of factors. Among these, socio-economic deprivation has been supposed to play a substantial role, although available evidence is not fully in agreement. Our study aimed to assess incidence and fatality rates of COVID-19 across the levels of socio-economic deprivation during the first epidemic wave (March–May 2020) in the Italian Province of Foggia, Apulia Region.
Methods
Based on the data of the regional active surveillance platform, we performed a retrospective epidemiological study among all COVID-19 confirmed cases that occurred in the Apulian District of Foggia, Italy, from March 1st to May 5th, 2020. Geocoded addresses were linked to the individual Census Tract (CT) of residence. Effects of socio-economic condition were calculated by means of the Socio-Economic and Health-related Deprivation Index (SEHDI) on COVID-19 incidence and fatality.
Results
Of the 1054 confirmed COVID-19 cases, 537 (50.9%) were men, 682 (64.7%) were 0–64 years old, and 338 (32.1%) had pre-existing comorbidities. COVID-19 incidence was higher in the less deprived areas (p < 0.05), independently on age. The level of socio-economic deprivation did not show a significant impact on the vital status, while a higher fatality was observed in male cases (p < 0.001), cases > 65 years (p < 0.001), cases having a connection with a nursing home (p < 0.05) or having at least 1 comorbidity (p < 0.001). On the other hand, a significant protection for healthcare workers was apparent (p < 0.001).
Conclusions
Our findings show that deprivation alone does not affect COVID-19 incidence and fatality burden, suggesting that the burden of disease is driven by a complexity of factors not yet fully understood. Better knowledge is needed to identify subgroups at higher risk and implement effective preventive strategies.
Journal Article
Early Warning Approach to Identify Positive Cases of SARS-CoV-2 in School Settings in Italy
by
Ruscio, Maurizio
,
Chilleri, Chiara
,
Malacarne, Francesca
in
Analysis
,
Asymptomatic
,
coronavirus disease
2025
During the COVID-19 pandemic, some studies suggested that transmission events could originate from schools. This study aimed to evaluate early-warning methods for identifying asymptomatic COVID-19 cases by implementing screening programs in schools. This study was conducted between September 2021 and May 2023, employing a rotation-screening plan for COVID-19 detection on a sample of students aged 14 to 19 years attending secondary schools in the regions of Tuscany, Veneto, Apulia and Friuli-Venezia Giulia. The schools were divided into two groups: experimental and control, with a ratio of 1:2. Two types of molecular salivary tests for SARS-CoV-2 were used to conduct the screening. This study included 16 experimental schools and 32 control schools. Out of 2527 subjects, 11,475 swabs were administrated, with 9177 tests deemed valid for analysis (a 20% loss of tests). Among these, 89 subjects (3.5%) tested positive. In control schools, 1895 subjects (6.5%) tested positive for SARS-CoV-2. This study recorded peaks in infections during the winter and autumn months, consistent with patterns observed in the general population. Beginning in September 2022, a shift occurred, with 2.6% of positive cases reported in the case schools compared to 0.3% in the control schools. Initially, most cases of COVID-19 were detected in the control schools; however, as the pandemic emergency phase concluded, cases were primarily identified through active screening in experimental schools. Although student participation in the active screening campaign was low during the project’s extension phase, this approach was efficacious in the early identification of positive cases.
Journal Article
Opinions and attitudes toward influenza vaccination among male Italian volleyball Serie A athletes in the 2024/25 season
by
Nuccetelli, Fabiana
,
Lopalco, Pier Luigi
,
Fortunato, Francesca
in
Athletes
,
Influenza
,
Prevention
2025
Influenza vaccination is a key preventive measure, especially for professional athletes exposed to increased infectious risk due to intense physical activity, frequent travel, and close-contact settings. However, data on vaccine uptake and attitudes in this group are limited. This study examined opinions, behaviors, and determinants of influenza vaccination adherence among male athletes in the Italian Serie A volleyball league during the 2024/25 season to inform targeted immunization strategies.
Cross-sectional observational study.
A self-administered anonymous questionnaire was distributed to 157 athletes between December 2024 and March 2025. Collected variables included socio-demographic characteristics, vaccination history, perceived influenza risk, vaccination importance, and influencing factors such as medical advice and club policy.
Of 138 respondents (response rate: 87.9 %), 44.9 % intended to vaccinate in the current season, and 63.8 % had been vaccinated previously. Overall, 76.1 % recognized the importance of vaccination. Key motivations were medical recommendations (61.6 %) and club policies (25.4 %). Significant associations were found between perceived influenza risk and vaccination intention (p < 0.001), and between medical recommendation and perceived importance (OR = 3.45, p < 0.01). Age showed no significant association.
Although vaccination is widely regarded as important among professional athletes, adherence is strongly influenced by organizational factors. Medical advice and club support are critical drivers of vaccine acceptance. Tailored communication strategies, integration of vaccination into routine sports medicine, and structured immunization programs are recommended to improve coverage in elite sports and support public health goals.
Journal Article
Cost of universal immunization with Nirsevimab vs. standard of practice for infants in their first RSV season. Foggia District, Italy, 2023–2024
by
Cristiano, Giuseppe
,
Lauriola, Marilena
,
Prato, Rosa
in
Allergy and Immunology
,
Antibodies, Monoclonal, Humanized - economics
,
Antibodies, Monoclonal, Humanized - therapeutic use
2025
This study assessed the direct costs of using Palivizumab for RSV prevention in the Foggia District, Italy, during the 2023/2024 season, and explored the cost savings coming from reallocating resources to Nirsevimab in a universal RSV program. Switching from Palivizumab to Nirsevimab could protect 57.85 % of newborns per season. Considering also hospitalization expenses, coverage reaches 46.4 % of infants, or 66.2 % if unspecified bronchiolitis is included. These results suggest notable cost savings and greater coverage, supporting a universal RSV initiative.
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Journal Article