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"Asiya"
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Allah gave me two hands and feet
A simple book describing the sense of touch, and why we should appreciate it. A classic title for Muslim children.
‘It Gets Really Boring if You Stay at Home’: Women, Work and Temporalities in Urban India
This article explores narratives of boredom among young lower middle class women employed in the bourgeoning services sector in India, across cafes, call centres, malls and offices. These young women cite boredom from ‘sitting at home’ as a reason to seek employment. Adopting Bourdieu’s understanding of temporal relations as informed by ‘subjective expectations’ and ‘objective chances’, I place young women’s temporal narratives in the context of post-1990 socio-economic change in India. I show that there is a shift in young lower middle class women’s expectations, particularly on the basis of acquisition of higher education. By rendering the space of home – characterised by compulsion to participate in housework, pressure to get married and restrictions on mobility and friendships – as temporally insignificant, young women resist gender norms. Their narratives contribute to gendering scholarship on temporal disruptions in the context of socio-economic change, which is currently overdetermined by young men’s experiences.
Journal Article
Allah gave me two ears to hear
An account of the sense of hearing given to us by Allah, which can be explored endlessly with young children.
Erythropoietin Protects Cardiomyocytes from Cell Death during Hypoxia/Reperfusion Injury through Activation of Survival Signaling Pathways
Hypoxia/Reoxygenation (H/R) cardiac injury is of great importance in understanding Myocardial Infarctions, which affect a major part of the working population causing debilitating side effects and often-premature mortality. H/R injury primarily consists of apoptotic and necrotic death of cardiomyocytes due to a compromise in the integrity of the mitochondrial membrane. Major factors associated in the deregulation of the membrane include fluctuating reactive oxygen species (ROS), deregulation of mitochondrial permeability transport pore (MPTP), uncontrolled calcium (Ca2+) fluxes, and abnormal caspase-3 activity. Erythropoietin (EPO) is strongly inferred to be cardioprotective and acts by inhibiting the above-mentioned processes. Surprisingly, the underlying mechanism of EPO's action and H/R injury is yet to be fully investigated and elucidated. This study examined whether EPO maintains Ca2+ homeostasis and the mitochondrial membrane potential (ΔΨm) in cardiomyocytes when subjected to H/R injury and further explored the underlying mechanisms involved. H9C2 cells were exposed to different concentrations of EPO post-H/R, and 20 U/ml EPO was found to significantly increase cell viability by inhibiting the intracellular production of ROS and caspase-3 activity. The protective effect of EPO was abolished when H/R-induced H9C2 cells were treated with Wortmannin, an inhibitor of Akt, suggesting the mechanism of action through the activation Akt, a major survival pathway.
Journal Article
The mechanisms of action of ivermectin against SARS-CoV-2—an extensive review
Considering the urgency of the ongoing COVID-19 pandemic, detection of new mutant strains and potential re-emergence of novel coronaviruses, repurposing of drugs such as ivermectin could be worthy of attention. This review article aims to discuss the probable mechanisms of action of ivermectin against SARS-CoV-2 by summarizing the available literature over the years. A schematic of the key cellular and biomolecular interactions between ivermectin, host cell, and SARS-CoV-2 in COVID-19 pathogenesis and prevention of complications has been proposed.
Journal Article
Low power and high-speed quadrate node upset tolerant latch design using CNTFET
Scalability, leakage, short-channel effects, and reliability problems are some of the difficulties facing the semiconductor industry as it continues to experience a reduction in size. Heavy charged particles striking an integrated circuit (IC) cause a Single Event Upset (SEU). As devices are scaled down, it usually causes Single and Multiple Node Upset. To overcome the upsets, device and CMOS circuit radiation hardening by design (RHBD) techniques are adopted. In the resent times, Carbon nanotubes have emerged as a feasible technology capable of addressing CMOS problems while maintaining performance and reliability. This manuscript proposes a Low power High speed Quadrate Node Upset Carbon Nanotube latch (LHQCNT). The LHQCNT latch contains three Dual Interlocked cells with a delta interconnection design, supplying enough redundant nodes to ensure robustness to Multi Node Upsets due to charge sharing. The investigation includes simulation, and performance comparison of a LHQCNT latch with an existing hardened latch. The LHQCNT latch obtained the power, delay, PDP and APDP as 4.4 µW, 1.23 ps, 5.41e-18 and 5.19e-2 respectively with a supply voltage of 1 V. Results from simulations show that the proposed LHQCNT latch archives low power, delay, and APDP of any latch with a comparable soft error tolerance level.
Journal Article
1,3-Diketone Calix4arene Derivatives—A New Type of Versatile Ligands for Metal Complexes and Nanoparticles
The present review is aimed at highlighting outlooks for cyclophanic 1,3-diketones as a new type of versatile ligands and building blocks of the nanomaterial for sensing and bioimaging. Thus, the main synthetic routes for achieving the structural diversity of cyclophanic 1,3-diketones are discussed. The structural diversity is demonstrated by variation of both cyclophanic backbones (calix[4]arene, calix[4]resorcinarene and thiacalix[4]arene) and embedding of different substituents onto lower or upper macrocyclic rims. The structural features of the cyclophanic 1,3-diketones are correlated with their ability to form lanthanide complexes exhibiting both lanthanide-centered luminescence and magnetic relaxivity parameters convenient for contrast effect in magnetic resonance imaging (MRI). The revealed structure–property relationships and the applicability of facile one-pot transformation of the complexes to hydrophilic nanoparticles demonstrates the advantages of 1,3-diketone calix[4]arene ligands and their complexes in developing of nanomaterials for sensing and bioimaging.
Journal Article
The Chaplin Vaccine: Immunization and Taylorism in Viktor Shklovsky's Theory and Fiction
The article examines early-Soviet figurations of cinema as a vaccine capable of inoculating workers with corporeal efficiency. Within this cultural fantasy, Charlie Chaplin was appropriated by the Soviet avant-garde to play an unlikely role of an expert in the theory and practice of labor. Tracing the cultural contexts of Chaplin's cameo in Iprit (1925), a science-fiction novel by Viktor Shklovsky and Vsevolod Ivanov, this article shows that the search for immunity from labor exhaustion opens wider vistas of the history of labor that run through the biocapital of slavery into the Soviet adoption of Taylorist practices of bodily standardization.
Journal Article