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Research about the role of religion in entrepreneurship and more broadly management is sparse. In this conceptual article, we complement existing entrepreneurship theory by examining entrepreneurship from an Islamic perspective (EIP). EIP is based on three interconnected pillars: the entrepreneurial, socio-economic/ethical, and religio-spiritual. We outline how Islam shapes entrepreneurship at the micro-, meso-, and macro-level, indicate how Islam may be considered an entrepreneurial religion in the sense that it enables and encourages entrepreneurial activity, review research streams interlinking Islam with entrepreneurship and management and outline promising research approaches.

Background and Objectives: Neuroblastoma is the most common extracranial solid tumor in children, often presenting challenges in treatment due to its clinical and genetic heterogeneity. This study investigated the anticancer potential of Pelargonium sidoides root extract on the human neuroblastoma cell line (SH-SY5Y). Using XTT assays, ELISA-based oxidative stress markers, and RT-PCR analysis of apoptotic genes, the study explored the extract’s effects on cell proliferation, oxidative stress, and apoptosis. Materials and Methods: For the cell culture, SH-SY5Y human neuroblastoma cells were thawed, cultured, and maintained under appropriate conditions for experiments. The dose- and time-dependent activity of Pelorgonium sidoides extract on SH-SY5Y neuroblastoma cells was investigated by XTT assay. The change in the oxidative stress marker 8-Hydroxy-2′-deoxyguanosine (8-OhDG) level was determined by ELISA for the doses applied to the control group root extract at a concentration of 25 μg/mL. Total antioxidant status (TAS) and total oxidant status (TOS) were measured from the cells in the study group with the help of a commercial kit. The oxidative stress index (OSI) was calculated by dividing the TAS by the TOS and multiplying by 100. In order to evaluate the expression levels of apoptosis-related Bax, Bcl-2, Caspase-3, Caspase-8, and Caspase-9 genes at the mRNA level in control and dose group cells, RNA isolation was performed from the SH-SY5Y control and dose group cells (IC50 value). Results: It is observed that the P. sidoides substance inhibits proliferation in cells at 24 h (p < 0.05). As the dose increases, cell proliferation decreases (p < 0.05). The IC50 value was calculated to be 113.83 μg/mL at 24 h. The concentration of 8-OhDG increased in neuroblastoma cells as a result of P. sidoides extract treatment (p < 0.05). TOS levels increased in neuroblastoma cells treated with P. sidoides extract (p < 0.01). OSI levels increased in cells treated with P. sidoides extract (p < 0.001). BAX and Caspase-8 expression increased are statistically significant in the P. sidoides dose group (p < 0.05). Conclusions: P. sidoides extract induces apoptosis in neuroblastoma cells through oxidative stress and mitochondrial- and death receptor-mediated pathways. This study highlights the potential of P. sidoides as a complementary therapeutic agent for neuroblastoma, warranting further in vivo and clinical investigations to assess its safety and efficacy.

Introduction/BackgroundEndometrial cancer (EC) is the most common gynecological malignancy throughout the world. Sentinel lymph node biopsy with indocyanine green (ICG) has become more widely used and has been featured in recently published guidelines for EC.MethodologyA 45-year-old female with gravidity 0, parity 0, and body mass index 23.4 kg/m2 presented with complaints of abnormal uterine bleeding (spotting). Increased endometrial thickness was detected on transvaginal ultrasound (10 mm) in the postmenstrual period. Endometrioid type endometrial adenocancer with focal squamous differentiation International Federation of Gynecology and Obstetrics (FIGO) grade 1 was detected on endometrial biopsy.Laparoscopic bilateral sentinel lymph node dissection with indocyanine green (ICG), hysterectomy (without uterine manipulator) + bilateral salpingo-oophorectomy were performed (video).ResultsThe patient stayed in hospital for 1 day. The final pathology result showed a FIGO grade 1, endometrioid type endometrial adenocancer with focal squamous differentiation, as a 1.5x 1 cm tumorous mass invading less than one-half of the myometrium. Neither lymphovascular invasion nor sentinel lymph node metastasis was detected.ConclusionThis video article is the first video demonstration of bilateral isolated high pelvic, para-aortic sentinel lymph node dissection in endometrial cancer.DisclosuresNo major complications occurred during or after the surgery.

Purpose: Today, the long-term effects of partial exposure of cholinesterase on the kidney continue to be a research topic. In this study, we aimed to histopathologically investigate the possible effect of acute toxicity due to fenthion, an organophosphate (OP) compound, on the kidneys. Methods: In all, 21 rats were randomly divided into three groups. Experimental group was each administered intraperitoneal 0.8 g/kg fenthion within physiologic serum. Sham group was only administered intraperitoneal physiologic serum. The control group continued normal nutrition with no procedure performed. After 24 h, all rats were sacrificed by cervical dislocation. Half of the recipient kidney tissues were examined histopathologically and the other half biochemically. Results: No histopathological findings were found in the control group. Rats in the experimental group were observed to have epithelial cell disorganization in tubules, moderate epithelial cell loss, and degeneration. Again, expansion of tubules, vacuolization of tubular epithelial cells, and tubular structure approaching atrophy were observed, with cells approaching apoptosis and common hemorrhage noted although rats in the sham group were observed to have mild tubular degeneration. Conclusions: It should not be forgotten that one of the causes of systemic complaints linked to acute toxicity exposed to the OP compound of fenthion may be cellular injury to glomerular and tubular structures in the kidneys.

Purpose - The purpose of this paper is to infer, from the mystical Islamic tradition, practical wisdom for management development on knowledge transfer and storage as well as organizational boundaries.Design methodology approach - This exploratory research uses an ethnographic approach. Deep immersion was sought through participant observation in a Sufi Dhikr Circle.Findings - Knowledge transfer and storage in the Sufi Dhikr Circle is a relational and collective endeavor. The Circle has fluid boundaries between the organization and the outside, as well as between intra-organizational parts. Knowledge and boundary processes reflect that the human being is a complex actor of \"body, mind and heart\" with multiple senses.Practical implications - Management development theory and practice may benefit through reflecting on the practices of the Sufi Dhikr Circle with regard to its group-collective, sense-comprehensive and actor-complex approach to knowledge storage and transfer, as well as the spatial, temporal and content fluidity both of intra-organizational boundaries in the Circle and vis-à-vis its environment. Conceptualizing the human as a complex actor with various senses may improve knowledge storage and transfer processes, as well as fluid de facto boundaries.Originality value - The observation of \"different practice\" which is shaped less by business discourse enables a critical reflection of \"common practice\" potentially leading to a new \"best practice\". Reflecting on the practices of the Sufi Dhikr Circle and its conceptualization of human beings may contribute to the management development literature and practice on knowledge and boundary processes. Contemplating on what is different may help us to better comprehend what is common.

Abstract Coronary cameral fistula (CCF) is defined as an abnormal connection between the coronary artery and the heart chambers. Although rare, most are asymptomatic, usually arising from the right coronary artery and terminating in the right ventricle or right atrium. Often detected incidentally, CCFs may present with symptoms of heart failure or rarely with anginal symptoms. Introduction A coronary cameral fistula is defined as an abnormal connection between the coronary artery and the heart chambers. CCFs are found in less than 1% of the population.[1] The most common coronary artery fistula is that arising from the right coronary artery and spilling into the right ventricle.[2] In particular, CCFs arising from all three epicardial coronary arteries are rare but can be clinically significant. These cases may present with acute coronary syndrome causing steal syndrome. Since there is usually no underlying obstructive lesion, these cases may be diagnosed as myocardial infarction without obstructive coronary arteries (MINOCA)[3] Case; A 51 years old male patient was admitted to the emergency room with a complaint of stabbing chest pain for the last one week. In his anamnesis, he described that the chest pain increased with exertion and radiated to the back. It was learned that he had no known disease and coronary history, was a 20 pack/year smoker, had no family history and was not taking any medication regularly. Vital signs in the emergency room revealed a blood pressure of 120/80 mmHg, pulse rate of 85 per minute and normal saturation. Electrocardiography (ECG) showed sinus rhythm V 1-6 with T negativity 85/min. (Figure 1) Echocardiography revealed no wall motion defect and no major valve pathology. Laboratory findings showed renal function tests within normal range, C-reactive protein within normal range, hemoglobulin level 17.6 gr/dl, HS Troponin-T level 12.9 ng/l (upper limit 14 ng/l). At 3 hours, the control HS Troponin-T level was 69.2 ng/l and the patient was hospitalized in the coronary intensive care unit with a prediagnosis of acute coronary syndrome. Coronary angiography was performed during follow-up. Angiography showed dilatation in the main coronary artery (LMCA), ectasia in the left anterior descending artery (LAD) and circumflex artery (CX), and diffuse tortuosity in the coronaries. CCF formed by the LAD, CX and right coronary artery (RCA) together and spilled into the left ventricle. Opaque filling was observed in the left ventricle. (Figure 2) Although the patient had a low body mass index, dilatation of the coronary arteries was thought to be the effect of steal syndrome caused by multiple fistulas. The patient was admitted to the coronary intensive care unit with medical follow-up. The patient's medical treatment was adjusted as acetylsalicylic acid (ASA) 100 mg pill 1*1, metaprolol 50 mg pill 1*1 and rosuvastatin 20 mg pill 1*1 due to an LDL cholesterol level of 149 mg/dl. In the patient who currently had no signs of heart failure, medical treatment was decided primarily in terms of CCF. The patient was discharged with the recommendation of outpatient follow-up. Discussion and Conclusion; CCFs are rare coronary anomalies.[1] When we look at the etiology, the most common cause of CCFs is abnormal embryogenesis.[4] While the diagnosis can be made at any age, the diagnosis is usually made in early childhood when a heart murmur occurs in an asymptomatic child or in a child with symptoms of heart failure. However, cases of CCF diagnosed at an advanced age with anginal complaints and signs of acute heart failure are seen in the literature. [5]Treatment depends on the anatomical features of the fistula and, of course, the patient's symptoms. While small fistulas may close spontaneously with age, large fistulas may require closure.It may cause anginal symptoms by causing heart failure symptoms and steal syndrome. [6]When we look at the literature, we can see that patients with CCF also present with acute coronary syndrome. [2, 4, 5,] As in the case reported by Alsancak Y et al., CCFs originating from all three coronary arteries cause steal syndrome and are often diagnosed with a prediagnosis of acute coronary syndrome.[7] The absence of an occlusive lesion after angiography in these patients with high troponin levels suggests atherosclerosis at the microvascular level and the diagnosis of MINOCA. [3]Angiography performed with suspicion of stenosis in the coronary arteries and finding a CHF instead of a stenosis may be considered lucky in these patients. The size of the fistula and the possibility that it may lead to heart failure in the follow-up will be the other side of the unlucky coin.

ObjectiveOn 6 February 2023, two massive earthquakes occurred in Kahramanmaras province in Türkiye. In addition to direct physical damage, earthquakes can also significantly affect individuals’ respiratory health in the postdisaster period. This study aimed to investigate respiratory diseases and related mortality following earthquakes.DesignThis is a retrospective observational study. 1 month following the earthquake, all cases that came to the emergency department between 6 February 2023 and 6 March 2023 who required a pulmonologist consultation were included (n=278). All cases requiring a pulmonologist consultation who were admitted to the emergency department within the same date period 1 year ago (6 February 2022–6 March 2022) were included in the control group (n=255).SettingTürkiye, Adana Province.Outcome measuresRespiratory diseases, mortality risks in 3 weeks and 3 months, and factors that may affect mortality were investigated in the population exposed to the earthquake.ResultsPneumonia had the highest rate among admissions in the postearthquake period (36.0%). The pneumonia rate and pneumonia-related deaths were significantly higher compared with those in the previous year (OR: 2.28, 95% CI: 1.05 to 4.94 and OR: 2.49, 95% CI: 1.15 to 5.39; 3-week and 3-month mortality, respectively). The disease that had the second highest admissions rate was chronic obstructive pulmonary disease exacerbation (25.9%). Earthquake exposure is associated with increased risk of 3-week (OR: 1.58, 95% CI: 1.03 to 2.43) and 3-month mortality (OR: 1.55, 95% CI: 1.03 to 2.36).ConclusionsThe period after the earthquake is associated with an increase in the incidence of pneumonia and a poor prognosis for patients with pneumonia. Considering all cases, earthquake exposure has a negative impact on the prognosis of respiratory diseases.

We aimed to evaluate computed tomography (CT) and magnetic resonance imaging (MRI) findings of cardiac calcified amorphous tumors (CATs). CT and MRI findings of cardiac CATs in 12 patients were included. We retrospectively examined patient demographics, location, size, shape configuration, imaging features, calcification distribution of tumors, and accompanying medical problems. There was a female predominance (75%), with a mean age at presentation of 65 years. Patients were mostly asymptomatic on presentation (58.3%). The left ventricle of the heart was mostly involved (91%). CT findings of CATs were classified as partial calcification with a hypodense mass in four patients or a diffuse calcified form in eight. Calcification was predominant with large foci appearance as in partially calcified masses. On T1- and T2-weighted magnetic resonance images, CATs appeared hypointense and showed no contrast enhancement. The shape and configuration of cardiac CATs are variable with a narrow spectrum of CT and MRI findings, but large foci in a partially calcified mass or diffuse calcification of a mass on CT is very important in the diagnosis of cardiac CATs. Masses show a low signal intensity on T1- and T2-weighted images with no contrast enhancement on MRI.

Adenosine deaminase (ADA) is an aminohydrolase involved in the catabolism of purine nucleotides and irreversibly deaminizes adenosine and deoxyadenosine to inosine and deoxyinosine. ADA enzyme deficiency results in the loss of functional properties of B and T lymphocytes. species have been reported to be transmitted between humans through close contact and to play a role in the pathogenesis of rosacea, acne vulgaris, perioral dermatitis, seborrhoeic dermatitis, micropapillary-pruritic dermatitis and blepharitis. The present study aimed to compare serum ADA levels in positive patients with the healthy control individuals. Serum ADA levels were examined for 30 patients diagnosed with erythematotelangiectatic rosacea and 40 healthy individuals in Malatya Inonu University in 2017. Standardized skin surface biopsy (SSSB) method was used to diagnose . A significant decrease was found in the ADA levels of -positive rosacea patients when compared to the control group. ADA levels were decreased in the -positive group. The mean ADA level in patient group was significantly lower than the mean in the control group ( <0.001). There was no significant difference between the patient and control groups in terms of age and gender. During and after treatment of -positive rosacea patients, determination of ADA levels may give more detailed information on the immune mechanisms.

Built on a critique of Serif Mardin's center-periphery approach, this study offers a discursive approach to the study of Turkish politics. Resting on the belief that the society is transparent to itself, Mardin asserts that society can exhaust the social and is always composed of a center and a periphery. By deploying Ernesto Laclau's discursive account of society, this study claims that society is not self-transparent; there is always a surplus of meaning in the social. Therefore, society consists solely of a center and its fate is tied on its success to monopolize the control of the center in the social. The advent of the political as a result of the emergence of alternative society-claim may threaten the existing social reality by revealing its contingency in representing the metaphorical totality of society. So from discourse theory perspective, political analysis should focus not on what society is but what prevents it from being. With this account of society, this study seeks to examine the rise and expansion of the Kemalist \"society\" as well as its dislocations owing to the emergence of other society-claims till the 1980s. Adapted from the source document.