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ObjectivesAs mainstreaming of genomic medicine is being implemented rapidly throughout paediatrics, it is critical that healthcare professionals are effectively upskilled in a timely fashion.1 Genomic Notes for Clinicians (GeNotes) is an NHS England National Genomics Education freely accessible online ‘just in time’ educational resource, designed to meet this need. It is aligned to the National Genomic Test Directory and supports clinicians, at the point of care, to identify when and how to request genomic tests and return results (‘In The Clinic’), and provides and extended learning opportunity (‘Knowledge Hub’). Paediatric content was launched on the public beta website in May 2023. We assessed usability, content and real-world use of the paediatric GeNotes resources.MethodsUsability testing took place in March 2022 and comprised user testing sessions in which participants completed a series of tasks using GeNotes by following a relevant clinical scenario. Data were collected via moderated user testing sessions, a feedback questionnaire and follow-up interviews. The sessions and interviews included a System Usability Scale (SUS) assessment.2 Live website analytics were undertaken to identify those pages most frequently accessed. Self-selection bias may affect the results as participants are likely to have a positive attitude towards genomics. We excluded IP addresses from National Genomics Education staff to avoid skewing the data on the pre-launch test site, however this was not possible for the live website.ResultsFive user testing sessions, 31 feedback surveys and 3 follow-up interviews were conducted. 61% of survey respondents were consultants and 39% were trainees working across quaternary, tertiary, secondary and community paediatrics across various UK regions. 91% said they would be likely or very likely to use GeNotes in the future. The mean SUS score was 86, indicating a high usability (the mean score for digital services is 68). Respondents reported that content is easy to navigate and appropriately detailed. Live website analytics identified that, between 14th June and 27th September 2023, there were 2,753 visits by 1,563 users to paediatric ‘In the Clinic’ pages, most frequently developmental delay/intellectual disability, macrocephaly, and suspected autism spectrum disorder.ConclusionUser testing suggests that GeNotes is a well-received, highly-usable educational resource appropriately pitched at paediatricians, which is being frequently accessed. Further work is required to expand the repository of resources in line with this rapidly evolving field, including resources to support Genomics England’s Generation Study, and to improve accessibility by exploring other routes of access, such as a mobile application.ReferencesAccelerating genomic medicine in the NHS, NHS England, 2022.Brooke J. SUS: A quick and dirty usability scale’ in Usability Evaluation in Industry, 1996.