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In this research, we studied the performance of different vegetative and fruits electrochemical cells namely PKL, Aloe Vera, Tomato and Lemon juice electrochemical cells with load condition for 2:1 Zn/Cu based electrodes. It was also studied the variation of Load Voltage (V L ), Load Current (I L ), and Load Power (P L ), with the variation of time for PKL, Aloe Vera, Tomato and Lemon juice electrochemical Cells. Among those cells the PKL electrochemical Cell was more efficient than the other three types of Cells regarding the load Current (I L ), Load Voltage (V L ), and Load Power (P L ). However, we investigated the performance of different types of Cells without load condition for 1:1 Zn/Cu based electrodes. Moreover, the variation of open circuit voltage (V oc ), short circuit current (I sc ) and maximum power (P max ) with the variation of time for those cells were explored. The discharge characteristic of the PKL electrochemical cell was more effective than the other three electrochemical Cells as the Open circuit voltage (V oc ), Short circuit current (I sc ) and Maximum Power (P max ) are more stable and steady in comparison with others. Heat treatment temperature was a new approach by which we can enhance the performance of these electrochemical cells. Most of the results have been tabulated and graphically discussed.

Aim: To compare the dosimetric advantage of stereotactic body radiotherapy (SBRT) for localized lung tumor between deep inspiration breath hold technique and free breathing technique. Materials and methods: We retrospectively included ten previously treated lung tumor patients in this dosimetric study. All the ten patients underwent CT simulation using 4D-CT free breathing (FB) and deep inspiration breath hold (DIBH) techniques. Plans were created using three coplanar full modulated arc using 6 MV flattening filter free (FFF) bream with a dose rate of 1400 MU/min. Same dose constraints for the target and the critical structures for a particular patient were used during the plan optimization process in DIBH and FB datasets. We intend to deliver 50 Gy in 5 fractions for all the patients. For standardization, all the plans were normalized at target mean of the planning target volume (PTV). Doses to the critical structures and targets were recorded from the dose volume histogram for evaluation. Results: The mean right and left lung volumes were inflated by 1.55 and 1.60 times in DIBH scans compared to the FB scans. The mean internal target volume (ITV) increased in the FB datasets by 1.45 times compared to the DIBH data sets. The mean dose followed by standard deviation (x̄ ± σx̄) of ipsilateral lung for DIBH-SBRT and FB-SBRT plans were 7.48 ± 3.57 (Gy) and 10.23 ± 4.58 (Gy) respectively, with a mean reduction of 36.84% in DIBH-SBRT plans. Ipsilateral lung were reduced to 36.84% in DIBH plans compared to FB plans. Conclusion: Significant dose reduction in ipsilateral lung due to the lung inflation and target motion restriction in DIBH-SBRT plans were observed compare to FB-SBRT. DIBH-SBRT plans demonstrate superior dose reduction to the normal tissues and other critical structures.

Temperature rise is a concern for future agriculture in different regions of the globe. This study aimed to reveal the future changes and variabilities in minimum temperature (Tmin) and maximum temperature (Tmax) in the monthly, seasonal, and annual scale over Bangladesh using 40 General Circulation Models (GCMs) of Coupled Model Intercomparison Project Phase 5 (CMIP5) for two radiative concentration pathways (RCPs, RCP4.5 and RCP8.5). The statistical downscaling climate model (SimCLIM) was used for downscaling and to ensemble temperature projections (Tmax and Tmin) for the near (2021–2060) and far (2071–2100) periods compared to the base period (1986–2005). Multi-model ensemble (MME) exhibited increasing Tmax and Tmin for all the timescales for all future periods and RCPs. Sen’s slope (SS) analysis showed the highest increase in Tmax and Tmin in February and relatively less increase in July and August. The mean annual Tmax over Bangladesh would increase by 0.61°C and 1.75°C in the near future and 0.91°C and 3.85°C in the far future, while the mean annual Tmin would rise by 0.65°C and 1.85°C in the near future and 0.96°C and 4.07°C in the far future, for RCP4.5 and RCP8.5, respectively. The northern and northwestern parts of the country would experience the highest rise in Tmax and Tmin, which have traditionally been exposed to temperature extremes. In contrast, the southeastern coastal region would experience the least rise in temperature. A higher increase in Tmin than Tmax was detected for all timescales, signifying a future decrease in the diurnal temperature range (DTR). The highest increase in Tmax and Tmin will be in winter compared to other seasons for both the periods and RCPs. The spatial variability of Tmax and Tmin changes can be useful for the long-term planning of the country.

In recent years, different biomaterials have garnered more research attention due to their usefulness as adsorbents. The present study focuses on a chemical treatment process to improve the adsorption capacity of betel nut husk fibers for a textile effluent (methylene blue). The fibers of chemically modified material were assessed using Fourier transform infrared (FTIR) spectrometer and Brunauer–Emmett–Teller (BET) analyzer to determine the existing surface functional groups and surface area, respectively. Parameters including contact time, dye concentration, temperature, effects of pH and desorption efficiency were also evaluated to identify optimum adsorption performance. Adsorption followed the Freundlich isotherm model and pseudo-first-order kinetics, indicating physisorption was responsible for adsorption and its occurrence on multilayers. Adsorption capacity was 149.921 mg/g, 149.874 mg/g and 145.462 mg/g at 30, 40 and 50, respectively, and was best at 30 °C. ΔH° was found to be − 1.494 which suggests adsorption is exothermic in nature and thus satisfying the findings that the physical process of adsorption took place in this study.

Using statistical response surface methodology this paper primarily investigates the role of process parameters at different levels (temperature, contact time, and rotation speed) and their influence on yield percentage during the production of chicken feather hydrochar (CFH) as soil amendment. Later, the produced char samples were evaluated before and after washing to assess the phytotoxic effect of seed germination and growth on Acacia auriculiformis through germination index% (GI). The optimized conditions for temperature, contact time, and rotation speed of hydrochar production were 150 °C, 1 h and 105.65 rpm, respectively. The hydrochar yield percentage at optimized conditions was 51.93%. The seed germination test indicated strong phytotoxicity for soil with untreated char, fresh hydrochar extract (FHE) with high doses, and 4 months old hydrochar extract (OHE) but the toxic effect was lower for washed hydrochar extract (WHE). It showed a higher germination rate and growth performance for washed hydrochar extract among all the doses. This study has confirmed the applicability of chicken feather (CF) hydrochar for improving the physical properties of sandy loam soil. Further research into pre-treatment and assessment of hydrochar before field application is required.

Nanocellulose, an exceptional natural material acquired from cellulose, has received tremendous attention over the past decades. This is because of its unique physical characteristics, surface chemistry, functional properties, and biocompatibility. Cellulose nanocrystals (CNCs) and cellulose nanofibers (CNFs) are two major types of nanocellulose that have received key interest so far. Nanocellulose is commercially produced from wood-based sources. With the ongoing demand for nanocellulose, agricultural wastes and non-woody plants are getting much consideration as cost-efficient alternatives. Water hyacinth (WH) is an alternative source that has shown great prospects for CNC and CNF fabrication. Nanocellulose from WH is proposed for several interesting applications, such as wet-spun filaments, aerogels, packaging films, battery separators, and water filtration, showing promising results. Studies have shown the nanocellulose achieved from WH has a comparable diameter and crystallinity related to the nanocellulose derived from other agricultural wastes, but lower than nanocellulose extracted from wood. Studies were more inclined towards chemical treatments for CNC extraction and mechanical processes for CNF isolation. This review aims to emphasize identifying the true potential of WH as a nanocellulose resource by critical evaluation of the isolation processes, affecting factors on nanocellulose properties, and the foundation of future research for producing sustainable materials. It was perceived that a lot of possibilities remain unexplored as many advanced techniques are yet not well studied for WH nanocellulose extraction. Further, the advantage of being a low-lignin raw material was not properly captured by mapping the more sustainable procedures, which should be a future highlight of WH research.

Internet Addiction (IA) is often shown to be associated with health issues, but no study explicitly examined a possible gradient in the association between different levels of IA and health. This study aimed to examine if the levels of IA had a graded relationship with poor sleep quality, psychological distress, and self-rated health among university students in Bangladesh. In this cross-sectional study, a sample of 625 students from six universities/colleges responded to an online survey that contained measures of internet addiction test (IAT), general health questionnaire (GHQ-12), sleep quality, and self-rated health. Modified Poisson regression models were fitted to estimate the adjusted risk ratios (RR) and confidence intervals (CI) of the associations between IA and health outcomes. The IA levels were associated with each of the three health outcomes in a linear fashion. Compared to the lowest IA quintile, the highest quintile remained associated with an increased risk of poor-quality sleeping (RR: 1.77; 95% CI: 1.26, 2.48), psychological distress (RR: 2.09; 95% CI: 1.55, 2.82), and worse self-rated health (RR: 1.46; 95% CI: 1.09, 1.96) after adjusting for socio-demographic covariates. There were also dose-response associations between IAT z-scores and health outcomes. The association between IAT z-scores and psychological distress was significantly stronger in males compared to females (p-value for interaction<0.05). The study found strong gradients between levels of addiction to internet and health outcomes, suggesting that increased health risks may exist even at lower levels of internet addiction. The findings highlight the need for departure of current research from a focus on the classic dichotomy of problematic versus not problematic internet use and a move toward recognizing the potential hierarchical effects of IA on health.

In August 2017, after a large influx of forcibly displaced Myanmar nationals (FDMN) in Cox's Bazar, Bangladesh diarrhea treatment centers (DTCs) were deployed. This study aims to report the clinical, epidemiological, and laboratory characteristics of the hospitalized patients. The study followed cross-sectional design. In total 1792 individuals were studied. Other than data, a single, stool specimen was subjected to one step rapid visual diagnostic test for Vibrio cholerae. The provisionally diagnosed specimens of cholera cases were inoculated into Cary-Blair Transport Medium; then sent to the laboratory of icddr,b in Dhaka to isolate the colony as well as perform antibiotic susceptibility tests. Data were analyzed by STATA and analyses included descriptive as well as analytic methods. Of the total 1792 admissions in 5 DTCs, 729 (41%) were from FDMN settlements; children <5 years contributed the most (n = 981; 55%). Forty percent (n = 716) were aged 15 years and above, and females were predominant (n = 453; 63%). Twenty-eight percent (n = 502) sought treatment within 24h of the onset of diarrhea. FDMN admissions within 24h were low compared to host hospitalization (n = 172, 24% vs. n = 330, 31%; p<0.001). Seventy-two percent (n = 1295) had watery diarrhea; more common among host population than FDMN (n = 802; 75% vs. n = 493; 68%; p<0.001). Forty-four percent admissions (n = 796) had some or severe dehydration, the later was common in FDMN (n = 46; 6% vs. n = 36; 3%, p = 0.005). FDMN often used public taps (n = 263; 36%), deep tube-well (n = 243; 33%), and shallow tube well (n = 188; 26%) as the source of drinking water. Nearly 96% (n = 698) of the admitted FDMN used pit latrines as opposed to 79% (n = 842) from the host community (p<0.001). FDMN children were often malnourished. None of the FDMN reported cholera. No diarrhea outbreak was detected, but preparedness for surges and response readiness are warranted in this emergency and crisis setting.

In April 2018, a diarrhea epidemic broke out in Dhaka city and adjoining areas, which continued through May. The Dhaka Hospital of the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), a dedicated diarrheal disease hospital, had a large upsurge in patient visits during the epidemic. An enhanced understanding of the epidemiology of this epidemic may help health-related professionals better prepare for such events in the future. This study examined the microbial etiology and non-pathogen factors associated with diarrhea during the epidemic. The study also evaluated the patients' presentation and clinical course and estimated the potential mortality averted by treating patients during the epidemic. Data from the patients who were treated at Dhaka Hospital during the diarrhea epidemic between April 2 and May 12, 2018 and were enrolled into the Diarrheal Disease Surveillance System (DDSS) at icddr,b were compared with the DDSS-enrolled patients treated during the seasonally-matched periods in the flanking years using logistic regression. icddr,b Dhaka Hospital treated 29,212 diarrheal patients during the 2018 epidemic period (and 25,950 patients per comparison period on average). Vibrio cholerae was the most common pathogen isolated (7,946 patients; 27%) and associated with diarrhea during the epidemic (adjusted odds ratio [AOR] 1.5, 95% CI: 1.1-2.0). The interaction of Vibrio cholerae with ETEC (AOR 2.7, 95% CI: 1.3-5.9) or Campylobacter (AOR 2.4, 95% CI: 1.1-5.1) was associated with further increased odds of diarrhea during the epidemic. In children under five years old, rotavirus was the most common pathogen (2,029 patients; 26%). Those who were adolescents (AOR 2.0, 95% CI: 1.3-3.1) and young adults (AOR 1.9, 95% CI: 1.4-2.5) compared to children younger than five years, resided within a 10 km radius of Dhaka Hospital (AOR 1.6, 95% CI: 1.1-2.2) compared to those living outside 20 km, borrowed money or relied on aid to pay for the transport to the hospital (AOR 1.6, 95% CI: 1.2-2.0), used tap water (AOR 1.8, 95% CI: 1.4-2.4) for drinking compared to tubewell water, and disposed of the solid waste directly outside the house (AOR 4.0, 95% CI: 2.7-5.9) were more likely to present with diarrhea during the epidemic. During the epidemic, patients were more likely to present with severe dehydration (odds ratio [OR] 1.6, 95% CI: 1.3-2.0) and require inpatient admission (OR 2.5, 95% CI: 1.9-3.3), intravenous rehydration (OR 1.7, 95% CI: 1.4-2.1), and antibiotics (OR 2.2, 95% CI: 1.8-2.7). The in-hospital case fatality rate was low (13 patients; 0.04%), and the hospital averted between 12,523 and 17,265 deaths during the epidemic. Vibrio cholerae played the primary role in the 2018 diarrhea epidemic in Dhaka. Campylobacter, enterotoxigenic Escherichia coli, and rotavirus had a secondary role. Adolescents and adults, residents of the metropolitan area, and those who were relatively poor and lacked safe water, sanitation, and hygiene (WASH) practices comprised the most vulnerable groups. Despite the increased disease severity during the epidemic, the case fatality rate was less than 0.1%. icddr,b Dhaka Hospital saved as many as 17,265 lives during the epidemic.

SARS-CoV-2 infection-induced aggravation of host innate immune response not only causes tissue damage and multiorgan failure in COVID-19 patients but also induces host genome damage and activates DNA damage response pathways. To test whether the compromised DNA repair capacity of individuals modulates the severity of COVID-19 infection, we analyze DNA repair gene expression in publicly available patient datasets and observe a lower level of the DNA glycosylase NEIL2 in the lungs of severely infected COVID-19 patients. This observation of lower NEIL2 levels is further validated in infected patients, hamsters and ACE2 receptor-expressing human A549 (A549-ACE2) cells. Furthermore, delivery of recombinant NEIL2 in A549-ACE2 cells shows decreased expression of proinflammatory genes and viral E-gene, as well as lowers the yield of viral progeny compared to mock-treated cells. Mechanistically, NEIL2 cooperatively binds to the 5’-UTR of SARS-CoV-2 genomic RNA to block viral protein synthesis. Collectively, these data strongly suggest that the maintenance of basal NEIL2 levels is critical for the protective response of hosts to viral infection and disease. NEIL2, a mammalian DNA repair enzyme, has been reported to suppress infection induced inflammation. Here, the authors characterize its role in modulating the severity of SARS-CoV-2 infection.