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Lewis Nordan
Lewis Nordan: Humor, Heartbreak, and Hope examines and celebrates the work of southern writer Lewis “Buddy” Nordan, whose stories reveal his own pain and humanity and in their honesty force us to recognize ourselves within them. Written by scholars and fiction writers who represent a fascinating range of experience—from a Shakespearean scholar to English professors to a former student of Nordan’s—this is a rich array of essays, poems, and visual arts in tribute to this increasingly important writer. The collection deepens the base of scholarship on Nordan, and contextualizes his work in relation to other important southern writers such as William Faulkner and Eudora Welty. Nordan was born and raised in Mississippi before moving to Alabama to pursue his Ph.D. at Auburn University. He taught for several years at the University of Arkansas in Fayetteville and retired from the University of Pittsburgh, where he was a professor of English. Nordan has written four novels, three collections of short stories, and a memoir entitled Boy with Loaded Gun . His second novel, Wolf Whistle , won the Southern Book Award, and his subsequent novel, The Sharpshooter Blues , won the Notable Book Award from the American Library Association and the Fiction Award from the Mississippi Institute of Arts and Letters. Nordan is renowned for his distinctive comic writing style, even while addressing more serious personal and cultural issues such as heartbreak, loss, violence, and racism. He transforms tragic characters and events into moments of artistic transcendence, illuminating what he calls the “history of all human beings.”
eBook
Albert Murray and the Aesthetic Imagination of a Nation
The first book-length study of the writings, work, and
life of Renaissance man and
Alabama
native Albert Murray This collection
consists of essays written by prominent African American
literature, jazz, and Albert Murray scholars, reminiscences from
Murray protégés and associates, and interviews with
Murray himself. It illustrates Murray’s place as a central
figure in African American arts and letters and as an American
cultural pioneer. Born in Nokomis, Alabama, and raised in Mobile,
Albert Murray graduated from Tuskegee University, where he later
taught, but he has long resided in New York City. He is the
author of many critically acclaimed novels, memoirs, and essay
collections, among them
The Omni-Americans ,
South to a Very Old Place, Train Whistle Guitar ,
The Spyglass Tree , and
The Seven League Boots . He is also a critic and visual
artist, as well as a lifelong friend of and collaborator with
artistic luminaries such as Ralph Ellison, Duke Ellington, and
Romare Bearden. As such, his life and work are testaments to the
centrality of southern and African American aesthetics in
American art. Murray is widely viewed as a figure who, through
his art and criticism, transforms the “fakelore” of
white culture into a new folklore that illustrates the centrality
of the blues and jazz idioms and reveals the black vernacular as
what is most distinct about American art.
eBook
Clinical, Histopathologic, and Biologic Features of Pleomorphic Lobular (Ductal-Lobular) Carcinoma In Situ of the Breast: A Report of 24 Cases
We reviewed 10 cases of pleomorphic lobular (ductal lobular) carcinoma in situ (PL/DLCIS) of the breast and compared them with 14 cases of pleomorphic lobular carcinoma in situ (PLCIS) found in association with invasive pleomorphic lobular carcinoma. The histologic features; immunohistochemical staining for estrogen receptors (ERs), p53, Ki67, E-cadherin, and gross cystic disease fluid protein-15 (GCDFP-15); and results of fluorescence in situ hybridization for HER-2/neu gene amplification were evaluated in all 24 cases. Histologically, PL/DLCIS cells were similar to those of PLCIS with invasion in that they were discohesive and medium to large in size with moderate to marked nuclear pleomorphism, small to prominent nucleoli, and moderate to abundant eosinophilic or vacuolated cytoplasm. In both groups, central necrosis was present in a small number of cases, and classic LCIS coexisted with the in situ lesion in less than half of the cases; in situ carcinomas were positive for ERs in 23 (100%) of 23 cases, p53 in 6 (25%) of 24 cases, and GCDFP-15 in 14 (74%) of 19 cases. The percentage of Ki67-positive tumor nuclei indicated moderate to high (more than 20%) proliferative activity in 8 (47%) of 17 cases. Immunostaining for E-cadherin was negative in all 24 cases. HER-2/neu gene amplification was observed in 1 (4%) of 23 cases. In cases with associated invasion, PLCIS had cytologic features and immunostaining patterns similar to those of the invasive pleomorphic component. Seven of the 10 patients who had PL/DLCIS without invasion underwent lumpectomy or simple mastectomy. Six of these patients had no evidence of disease in follow-up periods ranging from 4 to 32 months; the seventh patient developed recurrent disease 12 months after undergoing lumpectomy. We conclude that the cytologic features and biomarker expression profile of PL/DLCIS are similar to those of PLCIS with invasion but somewhat different from those of classic LCIS and ductal carcinoma in situ. Long-term follow-up studies are needed to further define the natural history of PL/DLCIS and its optimal management.
Journal Article
Abnormal glucose counterregulation after subcutaneous insulin in insulin-dependent diabetes mellitus
A study of glucose counter-regulation in 20 insulin-dependent diabetics during intensive insulin therapy revealed that 17 of the diabetics had more severe and prolonged hypoglycemia that non-diabetic control subjects matched for age and weight. Most of the patients had decreased activities of several counter-regulatory hormones. Marked rebound hyperglycemia subsequently developed in 11 of the patients. The rates of plasma glucose recovery from hypoglycemia correlated inversely with plasma free insulin levels (which correlated directly with insulin antibody binding). The implication of these results are discussed. (wz)
Journal Article