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Biosensing and bioimaging are essential in understanding biological and pathological processes in a living system, for example, in detecting and understanding certain diseases. Optical fiber has made remarkable contributions to the biosensing and bioimaging areas due to its unique advantages of compact size, immunity to electromagnetic interference, biocompatibility, fast response, etc. This review paper will present an overview of seven common types of optical fiber biosensors and optical fiber-based ultrasound detection in photoacoustic imaging (PAI) and the applications of these technologies in biosensing and bioimaging areas. Of course, there are many types of optical fiber biosensors. Still, this paper will review the most common ones: optical fiber grating, surface plasmon resonance, Sagnac interferometer, Mach–Zehnder interferometer, Michelson interferometer, Fabry–Perot Interferometer, lossy mode resonance, and surface-enhanced Raman scattering. Furthermore, different optical fiber techniques for detecting ultrasound in PAI are summarized. Finally, the main challenges and future development direction are briefly discussed.

Under the action of dynamic loadings such as earthquakes and volcanic activities, the mechanical properties of gas-hydrate-bearing sediments will deteriorate, leading to a decrease in the stability of hydrate reservoirs and even inducing geological disasters such as submarine landslides. In order to study the effect of dynamic loading on the mechanical properties of hydrate sediments, triaxial compression tests of numerical specimens were carried out by using particle flow code (PFC2D), and the macro-meso mechanical behaviors of specimens were investigated. The results show that the loading frequency has a small effect on the stiffness of the hydrate sediment, while it has a large effect on the peak strength. The peak strength increases and then decreases with the increase in loading frequency. Under the same loading frequency, the peak strength of the hydrate sediment increases with the increase in loading amplitude, and the stiffness of the specimen decreases with the increase in loading amplitude. The maximum shear expansion of the specimen changes with the movement of the phase change point and the rearrangement of the particles. The maximum shear expansion of the specimen changes with the movement of the phase change point and the change of the bearing capacity of the particles after the rearrangement, and the more forward the phase change point is, the stronger the bearing capacity of the specimen in the plastic stage. The shear dilatancy angle and the shear dilatancy amount both increase linearly with the increase in loading amplitude. The influence of loading frequency and amplitude on the contact force chain, displacement, crack expansion, and the number of cementation damage inside the sediment is mainly related to the average axial stress to which the specimen is subjected, and the number of cracks and cementation damage of the sediment specimen increases with the increase in the average axial stress to which the sediment specimen is subjected. As the rate of cementation damage increases, the distribution of shear zones becomes more obvious.

Understanding the shear properties of joints of rock masses is of great importance for engineering disaster prevention and control. In this paper, a systematic study of the macroscopic shear properties of joints of rock masses with different strengths is carried out using a combination of indoor tests and PFC2D numerical simulations. The results show that (i) the shear stress curve of low-strength rock joints is strain-softening type, while high-strength rock joints are strain-hardening type, and high-strength rock joints are more sensitive to the change of roughness. (ii) With the increase of JRC, the damage mode of different strength rock joints gradually changes from “abrasion” to “abrasion + gnawing,” and the damage characteristics of the surface of high-strength rock joints are more significant. (iii) The contact force between particles is mainly concentrated on the joints. At the beginning of shear, the contact force is mainly distributed on the second-order roughness and gradually concentrated on the first-order roughness as the shear progresses. Compared with the low-strength rock joints, the contact force on the high-strength rock joints is larger and more widely distributed. (iv) Due to the change of contact force, the cracks keep expanding and the particle rotation arc keeps changing. The particles with larger rotational arcs are consistent with the location of crack distribution, and the cumulative number of cracks on the joints of high-strength rock is higher. (v) The total input energy and dissipation energy increase continuously with the shear, and the elastic energy tends to increase at the beginning of shear and then starts to decrease and gradually tends to be constant near the peak of shear stress. The total input energy and dissipation energy of the joints of the high-strength rock are larger, while the peak elastic energy of it is smaller.

To study the shear deformation and failure characteristics of a wellbore and the interaction mechanism with its surrounding rocks induced by a layer slip during natural gas hydrates (NGHs) extraction, this paper conducted a numerical simulation study of wellbore shear induced by a layer slip using ABAQUS software and carried out a laboratory experiment of wellbore shear to verify the accuracy of the numerical model. The results show that the shear force–displacement curves obtained from the laboratory experiments and numerical simulations are consistent with five stages, including the compaction stage, linear stage, plastic stage, strain-softening stage and residual stage. The wellbore shows a “Z”-shaped deformation characteristic after its shear breakage. The shear force of the wellbore is maximum at the shear surface, and it is distributed in an approximate “M” shape along the shear surface. The axial force of the wellbore is small and uniformly distributed in the initial stage of the shear. The wellbore bending moment is minimum at the shear surface, with a value of 0, and it is distributed in a skew–symmetric wave shape along the shear surface. During the shearing, the evolution of the wellbore axial force and shear force can be classified into the distribution pattern along the radial direction on the shear surface and the pattern along the axial direction. The combination of the wellbore axial force and shear force causes the tensile–shear compound failure of the wellbore. During shearing, the wellbore and rock body gradually enter the plastic state with the increase in the shear displacement. When the entire cross-section of the wellbore is in the plastic state, a “necking” phenomenon of the wellbore begins to appear. During the shearing, the frictional dissipation energy and plastic dissipation energy increase constantly. In addition, the elastic strain energy increases to a peak and then decreases to a certain value, which remains unchanged along with the work conducted by the shear force.

Fiber quality is an important economic index and a major breeding goal in cotton, but direct phenotypic selection is often hindered due to environmental influences and linkage with yield traits. A genome-wide association study (GWAS) is a powerful tool to identify genes associated with phenotypic traits. In this study, we identified fiber quality genes in upland cotton ( L.) using GWAS based on a high-density CottonSNP80K array and multiple environment tests. A total of 30 and 23 significant single nucleotide polymorphisms (SNPs) associated with five fiber quality traits were identified across the 408 cotton accessions in six environments and the best linear unbiased predictions, respectively. Among these SNPs, seven loci were the same, and 128 candidate genes were predicted in a 1-Mb region (±500 kb of the peak SNP). Furthermore, two major genome regions (GR1 and GR2) associated with multiple fiber qualities in multiple environments on chromosomes A07 and A13 were identified, and within them, 22 candidate genes were annotated. Of these, 11 genes were expressed [log (1 + FPKM)>1] in the fiber development stages (5, 10, 20, and 25 dpa) using RNA-Seq. This study provides fundamental insight relevant to identification of genes associated with fiber quality and will accelerate future efforts toward improving fiber quality of upland cotton.

The aim of this study was to investigate the effects of dietary l-glutamine (Gln) supplementation on the morphology and function of the intestine and the growth of muscle in piglets. In this study, sixteen 21-day-old piglets were randomly divided into two groups: the Control group (fed a basal diet) and the Gln group (fed a basal diet supplemented with 0.81% Gln). Blood, gut, and muscle samples were collected from all piglets on Day 20 of the trial. Compared with the Control group, the supplementation of Gln increased (p < 0.05) the villus height, villus width, villus surface area, and villus height/crypt depth ratio of the small intestine. Furthermore, the supplementation of Gln increased (p < 0.05) total protein, total protein/DNA, and RNA/DNA in both the jejunum and ileum. It also increased (p < 0.05) the concentrations of carnosine and citrulline in the jejunal mucosa, as well as citrulline and cysteine concentrations in the ileum. Conversely, Gln supplementation decreased (p < 0.05) Gln concentrations in both the jejunum and ileum, along with β-aminoisobutyric acid and 1-Methylhistidine concentrations, specifically in the ileum. Subsequent research revealed that Gln supplementation increased (p < 0.05) the mRNA levels for glutathione-S-transferase omega 2 and interferon-β in the duodenum. In addition, Gln supplementation led to an increase (p < 0.05) in the number of Lactobacillus genus in the colon, but a decrease (p < 0.05) in the level of HSP70 in the jejunum and the activity of diamine oxidase in plasma. Also, Gln supplementation reduced (p < 0.05) the mRNA levels of glutathione-S-transferase omega 2 and interferon stimulated genes, such as MX1, OAS1, IFIT1, IFIT2, IFIT3, and IFIT5 in both the jejunum and ileum, and the numbers of Clostridium coccoides, Enterococcus genus, and Enterobacterium family in the colon. Moreover, Gln supplementation enhanced (p < 0.05) the concentrations of total protein, RNA/DNA, and total protein/DNA ratio in the longissimus dorsi muscle, the concentrations of citrulline, ornithine, arginine, and hydroxyproline, and the mRNA level of peptide transporter 1, while reducing the contents of hydrogen peroxide and malondialdehyde and the mRNA level of glutathione-S-transferase omega 2 in the longissimus dorsi muscle. In conclusion, dietary Gln supplementation can improve the intestinal function of piglets and promote the growth of the longissimus dorsi muscle.

In this paper, the finite-time synchronization problem has been investigated for a general array model of dynamical networks with time-varying delay and hybrid coupling. The Lyapunov functional method and linear matrix inequality technique are employed to obtain some synchronization criteria less-conservative and delay-dependent. Here, the coupling configuration matrices are not required to be symmetric or irreducible, neither is their off-diagonal entries assumed to be nonnegative. Moreover, the inner linking matrices are arbitrary real matrices. Finally, numerical examples are given to demonstrate the effectiveness of the proposed synchronous criteria.

Fiber strength is an important trait among cotton fiber qualities due to ongoing changes in spinning technology. Major quantitative trait loci (QTL) for fiber quality enable molecular marker-assisted selection (MAS) to effectively improve fiber quality of cotton cultivars. We previously identified a major QTL for fiber strength derived from 7235 in Upland cotton. In the present study, in order to fine-map fiber strength QTL, we chose three recombinant inbred lines (RIL), 7TR-133, 7TR-132, and 7TR-214, developed from a cross between 7235 and TM-1 for backcrossing to TM-1 to develop three large mapping populations. Phenotypic data for fiber strength traits were collected in Nanjing (JES/NAU) and Xinjiang (BES/XJ) in 2006 and 2007. Three simple sequence repeat (SSR) genetic linkage maps on Chro.24(D8) were constructed using these three backcrossed populations. The SSR genetic maps were constructed using 907 individuals in (7TR-133 x TM-1)F₂ (Pop A), 670 in (7TR-132 x TM-1)F₂ (Pop B), and 940 in (7TR-214 x TM-1)F₂ (Pop C). The average distance between SSR loci was 0.62, 1.7, and 0.56 cM for the three maps. MapQTL 5 software detected five-clustered QTL (2.5 < LOD < 29.8) on Chro.D8 for fiber strength following analysis of three RIL backcrossed F₂/F₂:₃ progenies at JES/NAU and BES/XJ over 2 years. Five QTL for fiber strength exhibited a total phenotypic variance (PV) of 28.8-59.6%.

High damping magnesium alloys have poor mechanical properties, so it is necessary to investigate the damping properties of high-strength wrought magnesium alloys to effectively reduce vibration and noise in mechanical engineering. The aim of this work is to improve the mechanical damping performance of a novel high-strength Mg-13Gd-4Y-2Zn-0.5Zr magnesium alloy by optimising the heat treatment process. The mechanical damping coefficient, considering not only damping capacity but also the yield strength, is selected as one of the evaluation indexes. The other evaluation index is the tensile strength. The solid solution and ageing treatment were optimised by Box-Behnken method, an efficient experimental design technique. Heat treatment experiments based on the optimal parameters verified that the best process is a solution at 520 °C for 10 h followed by ageing at 239 °C for 22 h. The damping coefficient reaches 0.296, which is 73.1% higher than that before heat treatment. There was a good agreement between the experimental and Box-Behnken predicted results. The microstructure, morphology and composition of the second phases after heat treatment were analysed by SEM, XRD and EDS. Due to the high content of alloying elements in Mg-13Gd-4Y-2Zn-0.5Zr alloy, there are a large number of second phases after heat treated. They mainly include layer, short rod-shaped, bulk long period stacking order (LPSO) Mg12YZn and granular Mg5Gd phases. It was found that the area fraction of the second phases has an extreme effect on the damping capacity and short rod-shaped LPSO can effectively improve the damping capacity of heat-treated Mg-13Gd-4Y-2Zn-0.5Zr alloy. The volume fraction of the second phases was analysed by ImageJ software. It was concluded that the smaller the area occupied by the second phases, the better the mobility of the dislocation, and the better the damping performance of the alloy. The statistical analysis results obtained using ImageJ software are consistent with the experimental results damping capacity.

In this article, we study a new hybrid synchronization scheme for two different delayed dynamical networks with nonidentical topologies and mixed coupling. Based on Barbalat lemma and Schur complement lemma, some hybrid synchronization criteria are achieved via the open‐loop‐plus‐pinning adaptive control strategy. Two numerical examples with two types of node dynamics illustrate the effectiveness of the proposed synchronous criteria. © 2016 Wiley Periodicals, Inc. Complexity 21: 470–482, 2016