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result(s) for
"Bazaka, Kateryna"
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Review on the Antimicrobial Properties of Carbon Nanostructures
2017
Swift developments in nanotechnology have prominently encouraged innovative discoveries across many fields. Carbon-based nanomaterials have emerged as promising platforms for a broad range of applications due to their unique mechanical, electronic, and biological properties. Carbon nanostructures (CNSs) such as fullerene, carbon nanotubes (CNTs), graphene and diamond-like carbon (DLC) have been demonstrated to have potent broad-spectrum antibacterial activities toward pathogens. In order to ensure the safe and effective integration of these structures as antibacterial agents into biomaterials, the specific mechanisms that govern the antibacterial activity of CNSs need to be understood, yet it is challenging to decouple individual and synergistic contributions of physical, chemical and electrical effects of CNSs on cells. In this article, recent progress in this area is reviewed, with a focus on the interaction between different families of carbon nanostructures and microorganisms to evaluate their bactericidal performance.
Journal Article
Prospects and physical mechanisms for photonic space propulsion
by
Mazouffre, Stephane
,
Xu, Shuyan
,
Levchenko, Igor
in
Ablation
,
Deep space
,
Electromagnetic radiation
2018
An abundant source of energy in space, electromagnetic radiation can provide spacecraft with a gentle yet persistent thrust for interplanetary and interstellar missions. Early successes with microlaser and solar propulsion platforms confirm their potential for near-Earth and deep space exploration, although practical realization of reliable photonic devices is not trivial. This Perspective outlines the recent achievements and future outlook in the field of photonic space propulsion. We highlight several light-enabled mechanisms of thrust generation via photon–matter interactions such as photonic pressure and ablation, optical gradient forces, light-induced electron emission and others. Finally, we outline some of the key challenges in the area and possible solutions for practical applications.
Journal Article
Metallic Biomaterials: Current Challenges and Opportunities
by
Collins, Cameron
,
Symes, Richard
,
Markwell, David
in
Biocompatibility
,
Biomedical materials
,
Dental implants
2017
Metallic biomaterials are engineered systems designed to provide internal support to biological tissues and they are being used largely in joint replacements, dental implants, orthopaedic fixations and stents. Higher biomaterial usage is associated with an increased incidence of implant-related complications due to poor implant integration, inflammation, mechanical instability, necrosis and infections, and associated prolonged patient care, pain and loss of function. In this review, we will briefly explore major representatives of metallic biomaterials along with the key existing and emerging strategies for surface and bulk modification used to improve biointegration, mechanical strength and flexibility of biometals, and discuss their compatibility with the concept of 3D printing.
Journal Article
Plasma and Polymers: Recent Progress and Trends
by
Baranov, Oleg
,
Xu, Shuyan
,
Ivanova, Elena
in
Adsorption
,
Atoms & subatomic particles
,
Electric fields
2021
Plasma-enhanced synthesis and modification of polymers is a field that continues to expand and become increasingly more sophisticated. The highly reactive processing environments afforded by the inherently dynamic nature of plasma media are often superior to ambient or thermal environments, offering substantial advantages over other processing methods. The fluxes of energy and matter toward the surface enable rapid and efficient processing, whereas the charged nature of plasma-generated particles provides a means for their control. The range of materials that can be treated by plasmas is incredibly broad, spanning pure polymers, polymer-metal, polymer-wood, polymer-nanocarbon composites, and others. In this review, we briefly outline some of the recent examples of the state-of-the-art in the plasma-based polymer treatment and functionalization techniques.
Journal Article
Effects of Atmospheric-Pressure N2, He, Air, and O2 Microplasmas on Mung Bean Seed Germination and Seedling Growth
2016
Atmospheric-pressure N
2
, He, air, and O
2
microplasma arrays have been used to investigate the effects of plasma treatment on seed germination and seedling growth of mung bean in aqueous solution. Seed germination and growth of mung bean were found to strongly depend on the feed gases used to generate plasma and plasma treatment time. Compared to the treatment with atmospheric-pressure O
2
, N
2
and He microplasma arrays, treatment with air microplasma arrays was shown to be more efficient in improving both the seed germination rate and seedling growth, the effect attributed to solution acidification and interactions with plasma-generated reactive oxygen and nitrogen species. Acidic environment caused by air discharge in water may promote leathering of seed chaps, thus enhancing the germination rate of mung bean, and stimulating the growth of hypocotyl and radicle. The interactions between plasma-generated reactive species, such as hydrogen peroxide (H
2
O
2
) and nitrogen compounds, and seeds led to a significant acceleration of seed germination and an increase in seedling length of mung bean. Electrolyte leakage rate of mung bean seeds soaked in solution activated using air microplasma was the lowest, while the catalase activity of thus-treated mung bean seeds was the highest compared to other types of microplasma.
Journal Article
Enhanced Antimicrobial Activity through Synergistic Effects of Cold Atmospheric Plasma and Plant Secondary Metabolites: Opportunities and Challenges
by
Weerasinghe, Janith
,
Prasad, Karthika
,
Sasi, Syamlal
in
Analysis
,
Antibacterial agents
,
antibiotic resistance
2023
The emergence of antibiotic resistant microorganisms possesses a great threat to human health and the environment. Considering the exponential increase in the spread of antibiotic resistant microorganisms, it would be prudent to consider the use of alternative antimicrobial agents or therapies. Only a sustainable, sustained, determined, and coordinated international effort will provide the solutions needed for the future. Plant secondary metabolites show bactericidal and bacteriostatic activity similar to that of conventional antibiotics. However, to effectively eliminate infection, secondary metabolites may need to be activated by heat treatment or combined with other therapies. Cold atmospheric plasma therapy is yet another novel approach that has proven antimicrobial effects. In this review, we explore the physiochemical mechanisms that may give rise to the improved antimicrobial activity of secondary metabolites when combined with cold atmospheric plasma therapy.
Journal Article
Synergic bactericidal effects of reduced graphene oxide and silver nanoparticles against Gram-positive and Gram-negative bacteria
by
Ostrikov, Kostya
,
Ostrikov, Kola
,
Bazaka, Kateryna
in
639/166/985
,
639/301/357
,
Anti-Bacterial Agents - chemistry
2017
Reduced graphene oxide (rGO) is a promising antibacterial material, the efficacy of which can be further enhanced by the addition of silver nanoparticles (nAg). In this study, the mechanisms of antibacterial activity of rGO–nAg nanocomposite against several important human pathogenic multi-drug resistant bacteria, namely Gram-positive coccal
Staphylococcus aureus
and Gram-negative rod-shaped
Escherichia coli
and
Proteus mirabilis
are investigated. At the same concentration (100 µg/ml), rGO–nAg nanocomposite was significantly more effective against all three pathogens than either rGO or nAg. The nanocomposite was equally active against
P. mirabilis
and
S. aureus
as systemic antibiotic nitrofurantoin, and significantly more effective against
E. coli
. Importantly, the inhibition was much faster in the case of rGO–nAg nanocomposite compared to nitrofurantoin, attributed to the synergistic effects of rGO–nAg mediated contact killing and oxidative stress. This study may provide new insights for the better understanding of antibacterial actions of rGO–nAg nanocomposite and for the better designing of graphene-based antibiotics or other biomedical applications.
Journal Article
Interaction of Atmospheric-Pressure Air Microplasmas with Amino Acids as Fundamental Processes in Aqueous Solution
by
Ostrikov, Kostya
,
Zhou, Renwu
,
Zhang, Xianhui
in
Amino acids
,
Amino Acids - chemistry
,
Analysis
2016
Plasma medicine is a relatively new field that investigates potential applications of cold atmospheric-pressure plasmas in bioengineering, such as for bacterial inactivation and degradation of organic molecules in water. In order to enunciate mechanisms of bacterial inactivation at molecular or atomic levels, we investigated the interaction of atmospheric-pressure air microplasmas with amino acids in aqueous solution by using high-resolution mass spectrometry (HRMS). Results show that the oxidation effect of plasma-induced species on the side chains of the amino acids can be categorized into four types, namely hydroxylation, nitration, dehydrogenation and dimerization. In addition, relative activities of amino acids resulting from plasma treatment come in descending order as follows: sulfur-containing carbon-chain amino acids > aromatic amino acids > five-membered ring amino acids > basic carbon-chain amino acids. Since amino acids are building blocks of proteins vital to the growth and reproduction of bacteria, these results provide an insight into the mechanism of bacterial inactivation by plasma.
Journal Article
Spectral characteristics of cotton seeds treated by a dielectric barrier discharge plasma
by
Ostrikov, Kostya (Ken)
,
Murphy, Anthony B.
,
Wang, Xing-Quan
in
631/449/2661
,
639/766/1960
,
Agricultural production
2017
Cold atmospheric plasma has recently emerged as a simple, low-cost and efficient physical method for inducing significant biological responses in seeds and plants without the use of traditional, potentially environmentally-hazardous chemicals, fungicides or hormones. While the beneficial effects of plasma treatment on seed germination, disease resistance and agricultural output have been reported, the mechanisms that underpin the observed biological responses are yet to be fully described. This study employs Fourier Transform Infrared (FTIR) spectroscopy and emission spectroscopy to capture chemical interactions between plasmas and seed surfaces with the aim to provide a more comprehensive account of plasma−seed interactions. FTIR spectroscopy of the seed surface confirms plasma-induced chemical etching of the surface. The etching facilitates permeation of water into the seed, which is confirmed by water uptake measurements. FTIR of exhaust and emission spectra of discharges show oxygen-containing species known for their ability to stimulate biochemical processes and deactivate pathogenic microorganisms. In addition, water gas, CO
2
, CO and molecules containing −C(CH
3
)
3
− moieties observed in FTIR spectra of the exhaust gas during plasma treatment may be partly responsible for the plasma chemical etching of seed surface through oxidizing the organic components of the seed coat.
Journal Article
Hopes and concerns for astronomy of satellite constellations
2020
The historic launch of the first several hundred out of 12,000 planned Starlink satellites heralds the arrival of the era of ultra-large satellite constellations. If it will bring new opportunities or insurmountable challenges to astronomy will probably depend on whether you are conducting your observations in space or from the surface of the Earth.
Journal Article