Search Results Heading

MBRLSearchResults

mbrl.module.common.modules.added.book.to.shelf
Title added to your shelf!
View what I already have on My Shelf.
Oops! Something went wrong.
Oops! Something went wrong.
While trying to add the title to your shelf something went wrong :( Kindly try again later!
Are you sure you want to remove the book from the shelf?
Oops! Something went wrong.
Oops! Something went wrong.
While trying to remove the title from your shelf something went wrong :( Kindly try again later!
    Done
    Filters
    Reset
  • Discipline
      Discipline
      Clear All
      Discipline
  • Is Peer Reviewed
      Is Peer Reviewed
      Clear All
      Is Peer Reviewed
  • Series Title
      Series Title
      Clear All
      Series Title
  • Reading Level
      Reading Level
      Clear All
      Reading Level
  • Year
      Year
      Clear All
      From:
      -
      To:
  • More Filters
      More Filters
      Clear All
      More Filters
      Content Type
    • Item Type
    • Is Full-Text Available
    • Subject
    • Publisher
    • Source
    • Donor
    • Language
    • Place of Publication
    • Contributors
    • Location
502 result(s) for "Bell, Erin"
Sort by:
The anthropology of expeditions : travel, visualities, afterlives
\"In the West at the turn of the twentieth century, public understanding of science and the world was shaped in part by expeditions to Asia, North America, and the Pacific. The Anthropology of Expeditions draws together contributions from anthropologists and historians of science to explore the role of these journeys in natural history and anthropology between approximately 1890 and 1930. By examining collected materials as well as museum and archive records, the contributors to this volume shed light on the complex social life and intimate work practices of the researchers involved in these expeditions. At the same time, the contributors also demonstrate the methodological challenges and rewards of studying these legacies and provide new insights for the history of collecting, history of anthropology, and histories of expeditions. Offering fascinating insights into the nature of expeditions and the human relationships that shaped them, The Anthropology of Expeditions sets a new standard for the field. \"-- Provided by publisher.
Determinants of maternal and neonatal PFAS concentrations: a review
Per- and polyfluoroalkyl substances (PFAS) are used for their properties such as stain and water resistance. The substances have been associated with adverse health outcomes in both pregnant mothers and infants, including pre-eclampsia and low birthweight. A growing body of research suggests that PFAS are transferred from mother to fetus through the placenta, leading to in utero exposure. A systematic review was performed using the PubMed database to search for studies evaluating determinants of PFAS concentrations in blood matrices of pregnant mothers and neonates shortly after birth. Studies were included in this review if an observational study design was utilized, exposure to at least one PFAS analyte was measured, PFAS were measured in maternal or neonatal matrices, at least one determinant of PFAS concentrations was assessed, and results such as beta estimates were provided. We identified 35 studies for inclusion in the review and evaluated the PFAS and determinant relationships among the factors collected in these studies. Parity, breastfeeding history, maternal race and country of origin, and household income had the strongest and most consistent evidence to support their roles as determinants of certain PFAS concentrations in pregnant mothers. Reported study findings on smoking status, alcohol consumption, and pre-pregnancy body mass index (BMI) suggest that these factors are not important determinants of PFAS concentrations in pregnant mothers or neonates. Further study into informative factors such as consumer product use, detailed dietary information, and consumed water sources as potential determinants of maternal or neonatal PFAS concentrations is needed. Research on determinants of maternal or neonatal PFAS concentrations is critical to estimate past PFAS exposure, build improved exposure models, and further our understanding on dose–response relationships, which can influence epidemiological studies and risk assessment evaluations. Given the potential for adverse outcomes in pregnant mothers and neonates exposed to PFAS, it is important to identify and understand determinants of maternal and neonatal PFAS concentrations to better implement public health interventions in these populations.
Quantifying the hidden carbon cost of floods: a stochastic and uncertainty-based valuation framework
Flood damage repairs to the built environment generate substantial greenhouse gas (GHG) emissions, yet these indirect climate impacts are rarely integrated into flood consequence assessments. In this study, we present a fragility-based modeling framework to estimate material replacement needs for building components damaged at specific flood depths. We develop fragility curves for each building component using a triangular cumulative distribution derived from expert judgment due to the lack of empirical data on flood losses, especially at the component level. By combining these estimates with life cycle GHG emissions for each component in a Monte Carlo simulation, we derive probabilistic, emissions-based damage curves for single-family residential structures which comprehensively account for uncertainty in the estimates. We then applied these damage curves to estimate the GHG emissions caused by a 100-year flood in two testbed regions in the Mississippi River Valley. Our results show that including the social costs of GHG emissions can increase the valuation of total flood damages by over 6%. Our results also show that flood impact estimates are highly uncertain our model can be used by planners in cost-benefit analyses of flood risk management projects to show that such projects are more economically efficient than current methods would report.
Generation gaps in US public opinion on renewable energy and climate change
The topics of climate change and renewable energy are often linked in policy discussions and scientific analysis, but public opinion on these topics exhibits both overlap and divergence. Although renewable energy has potentially broader acceptance than anthropogenic climate change, it can also face differently-based opposition. Analyses of US and regional surveys, including time series of repeated surveys in New Hampshire (2010-2018) and northeast Oregon (2011-2018), explore the social bases and trends of public views on both issues. Political divisions are prominent, although somewhat greater regarding climate change due to substantive differences and more partisan opposition. Regarding climate change and to a lesser extent renewable energy, political divisions tends to widen with education. There also are robust age and temporal effects: younger adults more often prioritize renewable energy development, and agree with scientists on the reality of anthropogenic climate change (ACC). Across all age groups and both regional series, support for renewable energy and recognition of ACC have been gradually rising. Contrary to widespread speculation, these trends have not visibly responded to events such as the US hurricanes of 2012, 2017 or 2018. Together with age-cohort replacement and the potential for changes in age-group voting participation, however, the gradual trends suggest that public pressure for action on these issues could grow.
Displacement of peer play by screen time: associations with toddler development
Background Young children’s digital media use may adversely affect child development, but the mechanisms of this association are unclear. We evaluated whether screen time displaces reading and peer play time, which are subsequently associated with child development. Methods When children were 12, 18, 24, 30, and 36 months, mothers ( n  = 3894) reported the time their children spent on screens, being read to by an adult, and playing with other children. At 36 months, mothers completed the Ages and Stages Questionnaire©, an assessment of their child’s developmental status. Results In unadjusted models, screen time from 12 to 36 months was not associated with reading but was associated with less time engaging in play with peers. In adjusted models accounting for developmental delay at 12 months, family and child characteristics, screen time was not directly associated with developmental delay. More peer play time was associated with a lower likelihood of developmental delay, and having higher screen time increased the likelihood of developmental delay indirectly through reduced peer play time. Results were similar for developmental delays in fine and gross motor, communication, and personal-social domains. Conclusions Screen time in early childhood did not displace reported time spent reading, but did displace reported peer play time. Impact Among children 1–3 years of age, more screen time was associated with less time engaged in peer play but not less reading with an adult. Having higher screen time from 1 to 3 years increased the odds of developmental delay indirectly through reduced peer play time. Ensuring that children engage in adequate time playing with peers may offset the negative associations between screen time and child development.
Exposure to Persistent Organic Pollutants and Birth Characteristics
BACKGROUND:Prenatal exposure to persistent organic pollutants (POPs) may be associated with obesogenic effects in offspring. Our study is the first to investigate associations between concentrations of POPs from newborn dried blood spots (DBS) and birth characteristics. METHODS:Concentrations of 10 polychlorinated biphenyl congeners (PCBs), polybrominated diphenyl ether-47 (PBDE-47), and p,p′-dichlorodiphenyldichloroethylene (p,p′-DDE) were measured from DBSs collected at birth from 2,065 singleton infants. DBS samples were pooled in groups of five and assayed together to reach limits of detection. Differences in risk of large for gestational age (LGA, defined as >90th percentile of birth weight for sex and gestational age), small for gestational age (SGA, <10th), and preterm birth (gestational age <37 weeks) were estimated using logistic regression per unit (ng/ml) increase in concentration of each chemical, adjusting for individual-level covariates, including maternal age, race/ethnicity, prepregnancy BMI, education, parity, smoking, and infant sex while assuming a gamma distribution and using multiple imputation to account for pools. RESULTS:There were 215 (11.3%) singletons born LGA, 158 (7.5%) born SGA, and 157 (7.6%) born preterm. Higher concentrations of POPs were positively associated with slightly higher risk of LGA and higher birth weight. CONCLUSIONS:Relationships between POPs measured in newborn DBS and birth size were mixed. Pooled analysis methods using DBS could address challenges in limits of detection and costs for population-based research.
A Multi-Objective Genetic Algorithm Approach to Sustainable Road–Stream Crossing Management
Road–stream crossings (RSCs) are vital for the sustainability of both stream ecosystems and transportation networks, yet many are aging, undersized, or failing. Limited funding and lack of stakeholder coordination hinder effective RSC management. This study develops a multi-objective optimization (MOO) framework utilizing the non-dominated sorting genetic algorithm (NSGA-II) to maximize and balance diverse stakeholder interests (i.e., environmental and transportation agencies) while minimizing management costs. MOO was used to identify optimal RSC management scenarios at a watershed scale, using the Piscataqua–Salmon Falls watershed, New Hampshire, as a testbed. It was found that MOO consistently outperformed the currently used scoring and ranking method by the environmental and transportation agencies, improving the environmental and transportation objectives by at least 19.56% and 37.68%, respectively, across all evaluated budget limits. These improvements translate to a maximum cost saving of USD 19.87 million under a USD 50 million budget limit. Structural conditions emerged as the most influential factor, with a Pearson coefficient of 0.60. This research highlights the potential benefits of a data-driven, optimization-based approach to sustainable RSC management.
A change in the wind? US public views on renewable energy and climate compared
Background Renewable energy development is a necessary step toward climate change mitigation, so these topics have often been linked. In US public discourse, however, they have somewhat different profiles—climate change views are tied closely to partisan identity, whereas renewable energy exhibits more cross-cutting appeal, and sometimes more cross-cutting opposition as well. To what extent are such differences reflected in survey data tracking rates of change, respondent characteristics, and local or regional variations in public opinion on renewable energy and climate? Methods We explore similarities and differences in views of renewable energy and climate change using a unique collection of 18 US national or regional surveys totaling more than 14,000 interviews, conducted between 2011 and 2017. Individual surveys varied in context, content, and goals, but all asked two common energy and climate questions, which yield comparable and strikingly consistent results. Results Public support for renewable energy appears broader than acceptance of anthropogenic climate change (ACC), especially in a more conservative region. Despite local controversies, support for renewable energy in recent years rose faster than ACC acceptance on two regional surveys. Political divisions remain wide on both topics, but wider regarding climate change—particularly among college-educated respondents. Renewable energy views in counties with proposed or operating wind farms are not systematically different from those in other counties. Conclusions Overall, these results provide encouragement for promoting renewable energy in terms of its economic benefits, working around some of the political identity-based resistance to climate change mitigation. That approach could be most important in politically conservative regions where such resistance is strong.
Faecal Microbiota of Cats with Insulin-Treated Diabetes Mellitus
Microorganisms within the gastrointestinal tract significantly influence metabolic processes within their mammalian host, and recently several groups have sought to characterise the gastrointestinal microbiota of individuals affected by metabolic disease. Differences in the composition of the gastrointestinal microbiota have been reported in mouse models of type 2 diabetes mellitus, as well as in human patients. Diabetes mellitus in cats has many similarities to type 2 diabetes in humans. No studies of the gastrointestinal microbiota of diabetic cats have been previously published. The objectives of this study were to compare the composition of the faecal microbiota of diabetic and non-diabetic cats, and secondarily to determine if host signalment and dietary factors influence the composition of the faecal microbiota in cats. Faecal samples were collected from insulin-treated diabetic and non-diabetic cats, and Illumina sequencing of the 16S rRNA gene and quantitative PCR were performed on each sample. ANOSIM based on the unweighted UniFrac distance metric identified no difference in the composition of the faecal microbiota between diabetic and non-diabetic cats, and no significant differences in the proportions of dominant bacteria by phylum, class, order, family or genus as determined by 16S rRNA gene sequencing were identified between diabetic and non-diabetic cats. qPCR identified a decrease in Faecalibacterium spp. in cats aged over ten years. Cat breed or gender, dietary carbohydrate, protein or fat content, and dietary formulation (wet versus dry food) did not affect the composition of the faecal microbiota. In conclusion, the composition of the faecal microbiota was not altered by the presence of diabetes mellitus in cats. Additional studies that compare the functional products of the microbiota in diabetic and non-diabetic cats are warranted to further investigate the potential impact of the gastrointestinal microbiota on metabolic diseases such as diabetes mellitus in cats.
Increased Axonal Ribosome Numbers Is an Early Event in the Pathogenesis of Amyotrophic Lateral Sclerosis
Myelinating glia cells support axon survival and functions through mechanisms independent of myelination, and their dysfunction leads to axonal degeneration in several diseases. In amyotrophic lateral sclerosis (ALS), spinal motor neurons undergo retrograde degeneration, and slowing of axonal transport is an early event that in ALS mutant mice occurs well before motor neuron degeneration. Interestingly, in familial forms of ALS, Schwann cells have been proposed to slow disease progression. We demonstrated previously that Schwann cells transfer polyribosomes to diseased and regenerating axons, a possible rescue mechanism for disease-induced reductions in axonal proteins. Here, we investigated whether elevated levels of axonal ribosomes are also found in ALS, by analysis of a superoxide dismutase 1 (SOD1)(G93A) mouse model for human familial ALS and a patient suffering from sporadic ALS. In both cases, we found that the disorder was associated with an increase in the population of axonal ribosomes in myelinated axons. Importantly, in SOD1(G93A) mice, the appearance of axonal ribosomes preceded the manifestation of behavioral symptoms, indicating that upregulation of axonal ribosomes occurs early in the pathogenesis of ALS. In line with our previous studies, electron microscopy analysis showed that Schwann cells might serve as a source of axonal ribosomes in the disease-compromised axons. The early appearance of axonal ribosomes indicates an involvement of Schwann cells early in ALS neuropathology, and may serve as an early marker for disease-affected axons, not only in ALS, but also for other central and peripheral neurodegenerative disorders.