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Infinite-layer nickelate thin films materialize an intriguing new platform for high-temperature unconventional superconductivity, with LaNiO2/SrTiO3 as reference setup. We discuss the relative stability of the elementary interfaces of this system and determine the corresponding electronic band structure. We find substantial changes compared to the bulk, in particular in relation to the 5d orbital contributions to the low-energy physics which can be totally replaced by purely Ni-3d flat bands. The d9 configuration characteristic of cuprates can thus be supplemented by an extra interfacial ingredient destabilizing the normal non-superconducting state in these heterostructures.

To evaluate treatment decision-making capacity (DMC) to consent to psychiatric treatment in involuntarily committed patients and to further investigate possible associations with clinical and socio-demographic characteristics of patients. 131 involuntarily hospitalised patients were recruited in three university hospitals. Mental capacity to consent to treatment was measured with the MacArthur Competence Assessment Tool for Treatment (MacCAT-T); psychiatric symptoms severity (Brief Psychiatric Rating Scale, BPRS-E) and cognitive functioning (Mini Mental State Examination, MMSE) were also assessed. Mental capacity ratings for the 131 involuntarily hospitalised patients showed that patients affected by bipolar disorders (BD) scored generally better than those affected by schizophrenia spectrum disorders (SSD) in MacCAT-T appreciation (p < 0.05) and reasoning (p < 0.01). Positive symptoms were associated with poorer capacity to appreciate (r = -0.24; p < 0.01) and reason (r = -0.27; p < 0.01) about one's own treatment. Negative symptoms were associated with poorer understanding of treatment (r = -0.23; p < 0.01). Poorer cognitive functioning, as measured by MMSE, negatively affected MacCAT-T understanding in patients affected by SSD, but not in those affected by BD (SSD r = 0.37; p < 0.01; BD r = -0.01; p = 0.9). Poorer MacCAT-T reasoning was associated with more manic symptoms in the BD group of patients but not in the SSD group (BD r = -0.32; p < 0.05; SSD r = 0.03; p = 0.8). Twenty-two per cent (n = 29) of the 131 recruited patients showed high treatment DMC as defined by having scored higher than 75% of understanding, appreciating and reasoning MacCAT-T subscales maximum sores and 2 at expressing a choice. The remaining involuntarily hospitalised patients where considered to have low treatment DMC. Chi-squared disclosed that 32% of BD patients had high treatment DMC compared with 9% of SSD patients (p < 0.001). Treatment DMC can be routinely assessed in non-consensual psychiatric settings by the MacCAT-T, as is the case of other clinical variables. Such approach can lead to the identification of patients with high treatment DMC, thus drawing attention to possible dichotomy between legal and clinical status.

Palù di Livenza is a Neolithic pile-dwelling site located in north-east Italy, inscribed since 2011 on the World Heritage List of UNESCO in the transnational serial property “Prehistoric pile-dwellings around the Alps”. Its study is crucial for investigating the transition from the Recent to Late Neolithic periods in the region. Eighteen vessels from 5 structural phases, dated approximately between 4300/4200 and 3600 BC, have been analysed using X-ray computed microtomography, X-ray diffraction, inductively coupled plasma optical emission and mass spectrometry, as well as portable X-ray fluorescence (pXRF), in order to investigate the pottery forming techniques, the technology and the provenance of the vessels based on their minero-petrographic and chemical characteristics. The results of pXRF analyses have been further evaluated through principal component analysis (PCA). The results obtained indicate that most of the vessels, including the four-spouted vessels typical of the Square Mouthed Pottery culture, were locally produced using the coiling technique. The vessels were tempered with carbonate material that has dissolved due to taphonomic factors and/or large fragments of other rocks originating form geological formations outcropping nearby the archaeological site. The identified fabric groups, in use throughout the entire duration of the settlement, seem to suggest that no significant technological changes occurred at the transition between Recent and Late Neolithic. Interestingly, the PCA analysis of reliable chemical elements revealed that, despite the overall similarity of the assemblage, certain samples with distinct chronology and typology demonstrate remarkably homogeneous chemical characteristics. This suggests slight variations in the raw materials and/or recipes used over time.

Aim of the current study is to investigate the associations between daily levels of air pollutants (particulate matter, ozone, carbon monoxide, nitrogen dioxide) and daily admissions for mental disorders to the emergency department of two general hospitals in Umbria region (Italy). We collected data about daily admissions to psychiatric emergency services of two general hospitals, air pollutants' levels and meteorological data for the time period 1 January 2015 until 31 December 2016. We assessed the impact of an increase in air pollutants on the number of daily admissions using a time-series econometric framework. A total of 1860 emergency department admissions for mental disorders were identified. We observed a statistically significant impact of ozone levels on daily admissions. The estimated coefficient of O3 is statistically significant at the 1% level. All other pollutants were not significantly associated with the number of daily admissions. Short-term exposure to ozone may be associated with increased psychiatric emergency services admissions. Findings add to previous literature on existing evidence for air pollution to have an impact on mental health. Ozone may be considered a potential environmental risk factor for impaired mental health.

In this paper we describe the macroseismic effects produced by the long and destructive seismic sequence that hit Central Italy from 24 August 2016 to January 2017. Starting from the procedure adopted in the complex field survey, we discuss the characteristics of the building stock and its classification in terms of EMS-98 as well as the issues associated with the intensity assessment due to the evolution of damage caused by multiple shocks. As a result, macroseismic intensity for about 300 localities has been determined; however, most of the intensities assessed for the earthquakes following the first strong shock on 24 August 2016, represent the cumulative effect of damage during the sequence. The earthquake parameters computed from the macroseismic datasets are compared with the instrumental determinations in order to highlight critical issues related to the assessment of macroseismic parameters of strong earthquakes during a seismic sequence. The results also provide indications on how location and magnitude computation can be strongly biased when dealing with historical seismic sequences.

Pnictogens and chalcogens are both viable anions for promoting Fe-based superconductivity, and intense research activity in the related families has established a systematic correlation between the Fe-anion height and the superconducting critical temperature Tc, with an optimum Fe-anion height of ~1.38 Å. Here, we report the discovery of superconductivity in the compound LaFeSiO1−δ that incorporates a crystallogen element, Si, and challenges the above picture: considering the strongly squeezed Fe–Si height of 0.94 Å, the superconducting transition at Tc = 10 K is unusually high. In the normal state, the resistivity displays non-Fermi-liquid behavior while NMR experiments evidence weak antiferromagnetic fluctuations. According to first-principles calculations, the Fermi surface of this material is dominated by hole pockets without nesting properties, which explains the strongly suppressed tendency toward magnetic order and suggests that the emergence of superconductivity materializes in a distinct set-up, as compared to the standard s±- and d-wave electron-pocket-based situations. These properties and its simple-to-implement synthesis make LaFeSiO1−δ a particularly promising platform to study the interplay between structure, electron correlations, and superconductivity.

Introduction/BackgroundThe OVHIPEC-1 phase III randomized trial has shown a statistically significant improvement in terms of Progression Free and Overall Survival in patients with advanced ovarian cancer, submitted to neoadjuvant chemotherapy (NACT), and receiving HIPEC at time of Interval Debulking Surgery (IDS).MethodologyAfter the publication of the trial, according to our national guidelines, the GYO Hospital Tumor Board decided to include HIPEC as routine practice, in patients achieving complete/optimal cytoreduction up to 2.5 mm at time of IDS. Procedure was performed according to published methods. Cases were collected prospectively to show rate of accrual, feasibility, complications.ResultsFrom January to April 2019, 40 patients were admitted to our Institution to receive IDS. Among them, 18 (45%) were not eligible due to the presence of strict pre-defined exclusion criteria (age >70 years old, uncontrolled chronic hyperthension, on-going treatment with ACE inhibitors, autoimmune disease, uncontrolled diabetes, BMI >35, ASA ≥3, patient included in other clinical trials). 4 women (10%) refused to sign informed consent. Finally, 18 patients had complete cytoreduction and received the planned treatment. Median Operative Time was 399 minutes (including 120 minutes related to HIPEC perfusion) (range 256–587) and median Estimated Blood Loss was 287.5 cc (50–600). 5 patients (29.4%) had grade 3 MSKCC early post-operative complications (3 pleural effusions requiring drainage, 2 wound dehiscence requiring VAC). Neither Acute Kidney Failure nor Grade 4–5 complications were observed.ConclusionAfter adopting strict inclusion criteria, the use of HIPEC in this specific setting of patients, has an accrual rate of 82% (18/22), and a feasibility rate after surgery of 100%. The major early complication rate is 27.8%. A larger number of patients is needed to draw significant conclusions.DisclosureNothing to disclose.

We study theoretically the fluoro-nickelate series ANiF2 (A = Li, Na, K, Rb, Cs) in the tetragonal P4/mmm infinite-layer structure. We use density functional theory to determine the structural parameters and the electronic band structure of these unprecedented compounds. Thus, we predict these materials as model d 9 systems where the Ni1 +  oxidation is realized and the low-energy physics is exclusively determined by the Ni-3d bands. Fluoro-nickelates of this class thus offer an ideal platform for the study of intriguing physics that emerges out of the special d 9 electronic configuration, notably high-temperature unconventional superconductivity.

A collection of polished stone axes from a late Neolithic site and an Early Bronze Age hill fort in South Tyrol (Italy) have been analysed through a multi-analytical approach, mainly based on non-destructive techniques (i.e. Raman spectroscopy, X-ray fluorescence and prompt gamma activation analysis) to identify the raw materials used in the same area during different periods and compare them with those in use in the surrounding territories. The analytical results suggest raw material exploitation strategies based on local or close sedimentary, metamorphic and magmatic rocks. Most of the artefacts are made from antigoritic serpentinite, whose origin is probably from Hohe Tauern (Austria) or related secondary deposits. These data confirm the importance of such raw material for the production of polished stone axes during recent prehistory and integrate the present knowledge about the distribution of antigoritic artefacts in north-eastern Italy and neighbouring countries.

In May–June 2012, the Po Valley (Northern Italy) was struck by an earthquake sequence whose strongest event occurred on 20 May (Mw 5.9). The intensity values (Imax 7–8 EMS98) assessed through macroseismic field surveys seemed inappropriate to describe the whole range of effects observed, especially those to monumental heritage, which suffered very heavy damage and destruction. The observed intensities in fact were significantly lower than those we could have expected after a Mw 5.9 event for Italy. As magnitude-intensity regressions are mainly based on historical earthquake data, we handle this issue going back in time and debating the following hypotheses: (a) the 2012 Emilia earthquake sequence shows lower intensity values than expected because the affected urban context is more heterogeneous and much less vulnerable than that in the past; (b) some historical earthquakes, especially those that occurred centuries ago and are provided with little information, could show a tendency to be overestimated in intensity, and consequently in magnitude. In order to give consistency to such hypotheses, we have introduced, as a test, a dual historical reading of the 2012 Emilia earthquake sequence as if it had occurred in the past: the first reading refers to a period prior to the introduction of concrete in buildings assessing the intensity on traditional masonry buildings only. A further historical reading, assessed by using information on monumental buildings only, was performed, and it can be roughly referred to the XVI–XVII centuries. In both cases, intensity values tend to grow significantly. The results could have a relevant impact when considered for seismic hazard assessments if confirmed on a large scale.