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Background: Studies have attempted to categorize organizational readiness by thoroughly comprehending its main components. However, few studies have examined it from the KM perspective. Objectives: The implementation of knowledge management (KM) initiatives frequently necessitates substantial organizational change. The first phase in preparing for such change is to conduct a change readiness assessment. This study investigated organizational readiness for KM implementation in a researchbased institution in Kuwait. Change progresses through the preparedness, adoption, and institutionalization phases. This study focuses on investigating the first phase of preparedness. Methods: This study followed a quantitative approach using a questionnaire to collect data. Four major factors-individual, context, content, and process attributes-were included as part of the readiness framework. They were used to explain the significant variance in organizational readiness towards KM implementation. Results: Individual attributes, context, content, and process measures clarified 84% of the variance in pessimism. Individual attributes and context, content, and process measures were also strongly associated with KM commitment, explaining 51% of the variance. This means that, as expected, respondents who reported greater readiness were more committed to KM initiatives and less pessimistic about them. Contribution: Evaluating the organizational readiness for KM initiatives is the first phase to help identify barriers and enablers to successful KM implementation. Based on the results of this study, organizational readiness for KM initiatives occurs when individuals exhibit a positive attitude toward KM implementation and high feelings of commitment. The results provide a roadmap for effective KM implementation and deliver practical guidelines for crafting KM policies.

Background Biologic grafts are increasingly used instead of synthetic mesh for parastomal hernia repair due to concerns of synthetic mesh-related complications. This systematic review was designed to evaluate the use of these collagen-based scaffolds for the repair of parastomal hernias. Methods Studies were retrieved after searching the electronic databases MEDLINE, EMBASE and Cochrane CENTRAL. The search terms ‘paracolostomy’, ‘paraileostomy’, ‘parastomal’, ‘colostomy’, ‘ileostomy’, ‘hernia’, ‘defect’, ‘closure’, ‘repair’ and ‘reconstruction’ were used. Selection of studies and assessment of methodological quality were performed with a modified MINORS index. All reports on repair of parastomal hernias using a collagen-based biologic scaffold to reinforce or bridge the defect were included. Outcomes were recurrence rate, mortality and morbidity. Results Four retrospective studies with a combined enrolment of 57 patients were included. Recurrence occurred in 15.7% (95% confidence interval [CI] 7.8–25.9) of patients and wound-related complications in 26.2% (95% CI 14.7–39.5). No mortality or graft infections were reported. Conclusions The use of reinforcing or bridging biologic grafts during parastomal hernia repair results in acceptable rates of recurrence and complications. However, given the similar rates of recurrence and complications achieved using synthetic mesh in this scenario, the evidence does not support use of biologic grafts.

In the current examination, insightful approximations are researched for mag-netohydrodynamics Carreau nanofluid having gyrotactic microorganisms over a warmed turning plate. The plate is moving with the steady uniform rakish speed. Administering conditions are gotten by utilizing certain actual presumptions as incomplete differential conditions with limit conditions. These nonlinear types of conditions are changed int o coupled Standard differential conditions utilizing bunch likeness change. Optimal homotopy investigation strategy Optimal Homotopy Asymptotic Method (OHAM) is utilized to acquire the graphical outcomes and even qualities for the stream field factors. Graphical portrayal of speeds, temperature, fixation and thickness of gyrotactic microorganisms are examined and clarified. It is tracked down that dimensionless microorganism's fixation develops for bioconvective Lewis number and focus distinction variable of microorganisms. It is additionally seen that dimensionless speeds diminish because of the attractive impact and Carreau liquid boundary. Contour plots and mathematical outcomes are given for neighbourhood motion boundaries like skin rubbing coëfficiënt, Nusselt number, Sherwood number and thickness number of motile microorganisms.

ObjectivesThe main objective of this study was to evaluate the sexual function in married menopausal women after surgery for non metastatic breast cancerMethodsThis is a prospective cohort-type study of 200 menopausal women diagnosed then operated on for breast carcinoma between January 2018 and March 2020. Patients were randomized after a multidisciplinary consultation in 2 groups: G1 with patients who had conservative breast surgery and G2 with those who had a mastectomy. Patients with immediate or delayed postoperative breast reconstruction were excluded. The data collection was done in an individual interview, in which 4 validated standardized psychometric assessment scales were used: The Arab Female Sexual Function Index (ArFSFI) for evaluation of sexual function The Locke and Wallace Marital Adjustment Test (MAT) for Assessment of Spousal Agreement The Hospital Anxiety and Depression Scale (HAD-S) for Assessment of Anxiety & Depression The Body-Esteem Scale for Adolescents and Adults (BESAA) for the evaluation of the body imageResultsThe two groups were comparable in terms of age and socio-economical characteristics of the patients and their spouses. The mean total FSFI scores were comparable (22 in G1vs 24.5 in G2, p = 0.084. There was a positive correlation between the husbands’ education level and the feminine sexual function (p = 0.042) and between marital agreement and sexual function (p = 0.004).ConclusionsThe technique of breast surgery for breast cancer does not influence the sexual function in menopausal women.

ObjectivesThe efficacy and utility of neoadjuvant chemotherapy (NAC) for Inflammatory breast cancer (IBC) are demonstrated. In node-negative patients after NAC, sentinel lymph node biopsy (SLNB) can be considered but not in IBC because of a low identification rate (IR) and a high false-negative rate(FNR). We aim to evaluate the SLNB identification fluorescence technique in this IBC population.MethodsBetween 2015 and 2019, data of all patients with NAC for carcinoma of the breast clinically classified as inflammatory (T4d) and without palpably suspicious nodes who underwent an SLNB during the definitive modified radical mastectomy with axillary clearance were retrospectively reviewed. Under general anesthesia 5 ml/12.5 mg of Infracyanine ® (Indocyanine green) were injected circumferentially around the areola; followed by a 15 min massage of the breast. The axillary incision was then performed and lymphatic vessels were visualized by a near-infrared camera. The sentinel node(s) were identified as being fluorescent and removed separately. After SLNB biopsy, mastectomy and axillary dissection were fully performed.ResultsA total of 22 patients with IBC underwent SLNB after NAC using the above-mentioned technique. The median age at the time of diagnosis was 44 years (range 25–62 years). The identification rate is 86% (19/22 patients). The false-negative rate was16% (2 patients among the 12 who had negative SLNB had a positive axilla lymph node examination).ConclusionsThe data of this study are encouraging but a larger sample is required. We do not have a clear explanation of why fluorescence provides better IR and lower FNR.

ObjectivesThe aim of this study was to evaluate the surgical morbidity and oncologic results on patients undergoing completion surgery for locally advanced-stage cervical cancer after initial concurrent chemo-radiotherapy (CCR).MethodsIt is a retrospective case/control study including all patients from 01/01/2000 to 31/12/2014 with advanced cervical cancer (stage IIB–IVA) treated with CCR (45 Gray pelvic external radiation therapy with concomitant chemotherapy (Cisplatin 40 mg/m2 per week) followed or not by uterovaginal brachytherapy) followed or not by surgery. Disease-free and overall survival rates at 3 and 5 years were compared.ResultsWe included 170 patients of whom 50 had CCR and catch-up surgery and 120 only CCR The two groups were comparable in terms of age at diagnosis, socio-economic characteristics of the patients, characteristics of the disease at diagnosis and after CCR. Hysterectomy was extra-fascial in 66% of cases. It was laparoscopic in 6% of cases. Pelvic lymphadenectomy was performed in 20% of cases. The operative complication rate was 23% with 12 immediate complications in 8 patients. The reoperation rate was 6%. The recurrence rate was 96% in the exclusive RCC group versus 66% in the surgery group with a significant difference in favor of surgery (p < 0.0001). The overall survival at 5 years after surgery was 55% versus 16% in the control group with a significant difference in favor of surgery (p < 0.0001).ConclusionsThe therapeutic impact of surgery based on completion hysterectomy with or without pelvic lymphadenectomy after CCR for locally advanced cervical cancer improved local disease control, overall and recurrence-free survival.

PurposeTo take full advantage of the unprecedented availability of information on networks and digital systems, professionals need to be comfortable finding information relevant to the tasks at hand. This study was conducted at the Kuwait Institute for Scientific Research to investigate scientists’ personal information management (PIM) practices.Design/methodology/approachA qualitative research approach was used. Critical incidents were collected to probe information about PIM activities. The PIM-related critical incidents were gathered through extended conversations in the form of semi-structured interviews.FindingsExtended conversations revealed that scientists were aware of the importance of information organization and management. They collected and received information from various sources regarding their tasks and saved part of the information for future use. Scientists organized saved information into named folders using the categories of projects, clients and planning. The files were updated by regular deletion and cleaning. Different strategies were used to retrieve the information. These included searching by keywords and file names, and browsing using the folder structure. Scientists have used various PIM tools. They reported that time pressure, information overload and anxiety due to information fragmentation were major challenges in PIM.Originality/valueThis study recommends a compilation of guidelines to assist scientists in the efficient management of personal information. As there are only a few studies currently available in the literature on scientists’ PIM, this study makes a valuable contribution to the relevant professional literature.

This study investigates the current coverage and treatment of strands of diversity in Library and Information Science (LIS) graduate curricula by examining 19 American Library Association (ALA) accredited Master of Library and Information Science (MLIS) programmes. The purpose is to analyze the depth and breadth of diversity-related topics in LIS programmes to determine the emphasis that LIS educators place on diversity-related content in the relevant coursework. Diversity-related topics were identified and categorized based on the published literature, and the contents of 84 course syllabi were examined. The findings show that while diversity-related topics are not prioritized in LIS programmes at present, the relevant content in curricula is increasing at a slow but significant rate. Diversity-related courses prepare aspiring librarians and information professionals to work with different cultural groups, young adults, and children. However, there is little interest in providing equitable services to minority groups in terms of gender and race/ethnicity, and people with disabilities. The findings of this study can provide a practical roadmap and useful insights for LIS educators, researchers, and practitioners.

ObjectivesThe core needle biopsy (CNB) is an attractive alternative to surgical biopsy for the purpose of characterizing completely a malignant breast lesion for a tailored management. The purpose of this work is to study the concordance of the molecular profile of invasive breast cancer between the CNB and definitive pathology examination.MethodsWe conducted a case-control study where each subject was her own control, including all patients with primary malignant tumors of the breast, collected prospectively, in our Department of Pathology and Cytology and treated at the Department of Gynecology and Obstetrics of the same hospital from January 1, 2015, to July 31, 2017. The studied molecular profile parameters were estrogen receptors (ER), progesterone receptors (PR), HER2 receptors (HER2), and Ki67.ResultsWe included 521 patients. The concordance between CNB and definitive postoperative specimen analysis with regard to the molecular profile parameters in invasive breast cancer was respectively of 100% and 96.3% for ER and PR, with an excellent agreement (respectively, k=1 and k= 0.905). The agreement in the diagnosis of tumors HER 2 overexpression was strong (k= 0.679). There was a difference between Ki 67 tumoral status (cut off at 20%) in CNB versus definitive postoperative specimen analysis in 53.1% of the cases with a weak agreement (k= 0.193). Consistency between CNB and postoperative specimen analysis in the distinction of luminal A tumors was 72.8%, 66.7% for luminal B, 90.1% for Her2 type and 86.4% for the basal type.ConclusionsCNB was reliable in determining the hormonal receptors’ status and the HER2 negative invasive breast cancer.

This study aimed to assess the prevalence of parasites of domestic pigeons ( ) and the histopathological changes associated with helminth parasites in their intestines. A total of 71 pigeons, 50 (30 males, 20 females) were examined for ectoparasites and 21(15 males, 7 females) for the presence of endoparasites (P-value 0.189). Thirty-six out of 50 pigeons (72 %) were infected with two species of ectoparasites (lice); was found in 30 pigeons out of 36 (83.33 %), while was found in 6 pigeons (P-value < 0.001). Fifteen out of 21 (71.4 %) pigeons were infected with endoparasites, out of which 12 (80 %) had one or more species of the total 6 species of cestodes, including (57.1 %), (57.1 %), (23.8 %), (9.52 %), (9.52 %) and (14.28 %). Three male pigeons (14.28 %) were found to be infected with only 1 species of nematode . All 12 pigeons (9 males, 3 females) were infected with R. tetragona and R. micracantha (57.1 %); additionally, all 12 showed triple parasitic infestation, having one other species of cestode in addition to these. Only 3 pigeons were found infected with the nematode . The prevalence of spp. was higher than that of other species. Males were found to be more infected than females (P-value 0.502). Histopathological fi ndings revealed destruction and shrinkage in the duodenum, necrosis and shrinkage of serosa and submucosa, villous atrophy and migratory tunnels formation, atrophic hyperplasia in the ileum, aggregate of infl ammatory lymphocytes at the lamina propria, infl ammation of villi in the rectum, cell death, infi ltration of lymphocytes, infl ammation and histological hyperplasia in the intestines. It was concluded that pigeons of the present locality were found infected with lice, cestode and nematode parasites that present a serious threat and might be injurious not only to pigeons but also to environmental contamination for humans and other animals. Further research is needed to identify the association and biological factors that affect humans.