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2 result(s) for "Birchall, Nicola"
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Feasibility of vocal fold abduction and adduction assessment using cine-MRI
Objective Determine feasibility of vocal fold (VF) abduction and adduction assessment by cine magnetic resonance imaging (cine-MRI) Methods Cine-MRI of the VF was performed on five healthy and nine unilateral VF paralysis (UVFP) participants using an axial gradient echo acquisition with temporal resolution of 0.7 s. VFs were continuously imaged with cine-MRI during a 10-s period of quiet respiration and phonation. Scanning was repeated twice within an individual session and then once again at a 1-week interval. Asymmetry of VF position during phonation (VF phonation asymmetry, VFPa) and respiration (VF respiration asymmetry, VFRa) was determined. Percentage reduction in total glottal area between respiration and phonation (VF abduction potential, VFAP) was derived to measure overall mobility. An un-paired t-test was used to compare differences between groups. Intra-session, inter-session and inter-reader repeatability of the quantitative metrics was evaluated using intraclass correlation coefficient (ICC). Results VF position asymmetry (VFPa and VFRa) was greater ( p =0.012; p =0.001) and overall mobility (VFAP) was lower ( p =0.008) in UVFP patients compared with healthy participants. ICC of repeatability of all metrics was good, ranged from 0.82 to 0.95 except for the inter-session VFPa (0.44). Conclusion Cine-MRI is feasible for assessing VF abduction and adduction. Derived quantitative metrics have good repeatability. Key points • Cine-MRI is used to assess vocal folds (VFs) mobility: abduction and adduction. • New quantitative metrics are derived from VF position and abduction potential. • Cine-MRI able to depict the difference between normal and abnormal VF mobility. • Cine-MRI derived quantitative metrics have good repeatability.
Taxation
Update on ORIP From 6 April 2019, non-UK residents in certain (generally lowtax) jurisdictions will be liable to UK income tax on their gross receipts from the exploitation of intangible property rights to the extent those receipts enable, facilitate, or support UK-based sales of goods or services. If retailer B uses that IP to manufacture goods and makes direct sales to customers based in the United Kingdom, then ORIP would apply to the licence fee received by brand owner A. (UK sales include online advertising services targeted at UK persons.) The challenge is being able to trace through often complex supply chains to determine whether IP licenses which are between entirely off-shore parties are nevertheless supporting UK sales. [...]DST is expected to affect a relatively small number of large multinational groups.