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"Brandão, Isabel"
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Impact of COVID-19 lockdown measures on a cohort of eating disorders patients
by
Gonçalves, Sónia
,
Rodrigues, Tânia F.
,
Machado, Paulo P. P.
in
Analysis
,
Anorexia
,
Behavioral Science and Psychology
2020
Background
Lockdown implemented to prevent the COVID-19 spread resulted in marked changes in the lifestyle. The objective of the current study was to assess the impact of lockdown measures on a cohort of eating disorder (ED) patients being followed as part of an ongoing naturalistic treatment study.
Methods
Ninety-nine patients aged 18 or older, currently or previously, in treatment at a Portuguese specialized hospital unit were contacted by phone and invited to participate in the current survey. Fifty-nine agreed to be interviewed by phone, and 43 agreed to respond to a set of self-report measures of ED symptoms, emotion regulation difficulties, clinical impairment, negative urgency, and COVID-19 impact, during the week after the end of the lockdown period.
Results
Data showed that of the 26 patients currently in treatment: 8 remained unchanged (31%), 7 deteriorated (27%), and 11 reliably improved (42%). Of the 17 participants not currently in treatment: 3 deteriorated (18%), 9 remained unchanged (53%), and 5 (29%) improved after the lockdown period. The Coronavirus Impact Scale showed that most patients considered their routines moderately or extremely impacted, experienced stress related to coronavirus, and showed difficulty in maintaining physical exercise and feeding routines. Results suggest that higher impact of COVID-19 lockdown was significantly correlated with eating disorder symptoms and associated psychopathology, impulsivity, difficulties in emotion regulation and clinical impairment measured at post-lockdown. In addition, the impact of COVID-19 and lockdown measures on clinical impairment was mediated by difficulties in emotion regulation.
Conclusions
Findings suggest that some ED patients may experience worsening of their condition, especially if associated with difficulties in emotion regulation, and these difficulties might be exacerbated in the context of a stressful crisis and lockdown measures, highlighting the need for intervention strategies to mitigate its negative impact.
Journal Article
Orofacial manifestations in outpatients with anorexia nervosa and bulimia nervosa focusing on the vomiting behavior
2018
ObjectiveThis case-control study aims to evaluate the oral health status and orofacial problems in a group of outpatients with eating disorders (ED)—either anorexia nervosa (AN) or bulimia nervosa (BN)—further focusing on the influence of vomit.Materials and methodsFifty-five women outpatients with AN or BN diagnosis were invited to participate, of which 33 agreed. ED outpatients and matched controls were submitted to a questionnaire and clinical oral examination.ResultsMultivariate analysis identified a significantly higher incidence of teeth-related complications (i.e., tooth decay, dental erosion, and self-reported dentin hypersensitivity), periodontal disease, salivary alterations (i.e., hyposalivation and xerostomia), and oral mucosa-related complications in ED outpatients. Dental erosion, self-reported dentin hypersensitivity, hyposalivation, xerostomia, and angular cheilitis were found to be highly correlated with the vomiting behavior.ConclusionsED outpatients were found to present a higher incidence of oral-related complications and an inferior oral health status, compared to gender- and age-matched controls. Alterations verified within outpatients were acknowledged to be quite similar to those previously reported within inpatients, in both of nature and severity, thus sustaining that the cranio-maxillofacial region is significantly affected by ED, even in the early/milder forms of the condition, as expectedly verified within outpatients.
Journal Article
Pregnancy and Pregnancy Outcomes in Women with Eating Disorders: A Four-Year Longitudinal Study with Case Series
by
Gonçalves, Sónia
,
Machado, Bárbara César
,
Duarte, Sofia
in
Anorexia
,
Baby and childern's development
,
baby and children’s development
2025
Background/Objectives: Eating disorders (EDs) often affect fertility, yet many women with ED still become mothers. The pattern of ED symptoms during pregnancy and postpartum, along with their effects on maternal and child health, is not yet fully understood. This longitudinal study aimed to (1) examine the course of ED symptoms from conception to postpartum, (2) evaluate pregnancy outcomes and children’s health and developmental milestones, and (3) assess ED status approximately four years after the initial evaluation. Methods: Thirty women with a prior ED diagnosis (21 with anorexia nervosa, 9 with bulimia nervosa) were evaluated at two time points. Time 1 with the Eating Disorders Examination and the Oxford Risk Factors for Eating Disorders: Interview Schedule; Time 2, approximately four years later, with the Eating Disorders Examination and the Clinical Interview on Reproductive History and Eating Behavior that also included clinical data related to mother’s health and baby’s health and development accessed through the Pregnant Women’s Health Bulletin and the Child and Youth Health Bulletin using the national health records. Results: ED symptoms (dietary restriction, self-induced vomiting, laxative misuse) persisted from conception through postpartum. BN participants reported more severe symptoms and higher rates of pregnancy complications (hyperemesis gravidarum, gestational diabetes, preeclampsia), while premature births occurred only in AN participants. Children of mothers with AN more frequently showed delays in developmental milestones (sitting, walking, speaking, sphincter control) compared to those of BN mothers. Conclusions: A substantial proportion of women with prior ED continued to experience symptoms during and after pregnancy, and nearly half still met diagnostic criteria four years later and are still in treatment. Cognitive features such as body dissatisfaction persisted despite partial symptom remission. These findings highlight the chronicity of ED and underscore the need for systematic screening, psychological support, and interdisciplinary follow-up during pregnancy and early motherhood.
Journal Article
Psychometric properties of the Portuguese version of the Yale Food Addiction Scale
2017
Purpose
Rising rates of obesity have been recently associated to the novel concept of food addiction (FA). The Yale Food Addiction Scale (YFAS) is the most widely used measure for examining FA (
1
) and analysis of its reliability and validity is expected to facilitate empirical research on the construct. Here, we tested the psychometric properties of a Portuguese version of the YFAS (P-YFAS), establishing its factor structure, reliability and construct validity.
Methods
Data were obtained from 468 Portuguese individuals, 278 sampled from non-clinical populations, and 190 among obese candidates for weight-loss surgery. A battery of self-report measures of eating behavior was applied.
Results
Confirmatory factor analysis verified a one-factor structure with acceptable fit, with item analysis suggesting the need to eliminate item 24 from the P-YFAS. Internal consistency (KR-20 = .82) and test–retest stability were adequate. Correlation analyses supported convergent and divergent validity of the P-YFAS, particularly in the clinical sample. Both FA symptom count and diagnosis, according to the P-YFAS, adequately discriminated between samples, with classification of FA met by 2.5 and 25.8% of the participants in the non-clinical and clinical samples, respectively.
Conclusions
These findings reinforce the use of P-YFAS in non-clinical and clinical populations. Future directions for extending YFAS validation are discussed.
Journal Article
Factorial Validity of the Toronto Alexithymia Scale (TAS-20) in Clinical Samples: A Critical Examination of the Literature and a Psychometric Study in Anorexia Nervosa
by
Rocha, Magda
,
Guerra, Marina P.
,
Costa, Patrício
in
Adolescent
,
Adult
,
Affective Symptoms - complications
2019
There is extensive use of the 20-item Toronto Alexithymia Scale (TAS-20) in research and clinical practice in anorexia nervosa (AN), though it is not empirically established in this population. This study aims to examine the factorial validity of the TAS-20 in a Portuguese AN sample (
N
= 125), testing four different models (ranging from 1 to 4 factors) that were identified in critical examination of existing factor analytic studies. Results of confirmatory factor analysis (CFA) suggested that the three-factor solution, measuring difficulty identifying (DIF) and describing feelings (DDF), and externally oriented thinking (EOT), was the best fitting model. The quality of measurement improves if two EOT items (16 and 18) are eliminated. Internal consistency of EOT was low and decreased with age. The results provide support for the factorial validity of the TAS-20 in AN. Nevertheless, the measurement of EOT requires some caution and may be problematic in AN adolescents.
Journal Article
Using Synergy between Water Limnology and Satellite Imagery to Identify Algal Blooms Extent in a Brazilian Amazonian Reservoir
2017
Monitoring algal blooms from space is a very challenging task, which becomes particularly difficult when dealing with cyanobacteria blooms. Cyanobacteria are strategic organisms adapted to a wide variety of environmental conditions. In high concentrations, they form scum on the water surface, which is a concern for public health due to the production of toxins, as well as being a nuisance. Knowledge of the ecological role of these organisms is, therefore, essential when trying to estimate their extent from satellite-based data. We present a multidisciplinary approach, based on both the ecological and the optical perspective. This approach is applied in a Brazilian Amazonian reservoir using spatial and temporal scales. The ACOLITE processor is employed to perform atmospheric correction. Extent of the algal bloom is mapped with outputs such as Rayleigh reflectance atmospheric corrected images. Chlorophyll-a estimation is accomplished using a blue-green edge algorithm from the Ocean Biology Processing Group (OBPG), and shows reasonable results (R2 = 0.95; RMSE = 0.40). The SAred-NIR slope algorithm identifies the extent of the algal bloom at both the spatial and temporal scale. Unfortunately, the performance of these algorithms is most likely affected by weather conditions and glint effects. Therefore, this study recommends that cyanobacteria or phytoplankton studies in this area ensure that their ecological functioning is carefully considered when attempting to map occurrence using limited satellite imagery.
Journal Article
Prediabetes remission after bariatric surgery: a 4-years follow-up study
by
Silva, Maria Manuel
,
Gil-Santos, Sara
,
Menino, João
in
Analysis
,
Antidiabetics
,
Bariatric surgery
2024
Background
Bariatric surgery leads to weight loss and to cardiometabolic risk improvement. Although prediabetes remission after bariatric surgery is biologically plausible, data on this topic is scarce. We aimed to assess prediabetes remission rate and clinical predictors of remission in a 4 year follow up period.
Methods
Observational longitudinal study including patients with obesity and prediabetes who had undergone bariatric surgery in our centre. Prediabetes was defined as having a baseline glycated haemoglobin (A1c) between 5.7% and 6.4% and absence of anti-diabetic drug treatment. We used logistic regression models to evaluate the association between the predictors and prediabetes remission rate.
Results
A total of 669 patients were included, 84% being female. The population had a mean age of 45.4 ± 10.1 years-old, body mass index of 43.8 ± 5.7 kg/m
2
, and median A1c of 5.9 [5.8, 6.1]%. After bariatric surgery, prediabetes remission rate was 82%, 73%, 66%, and 58%, respectively in the 1st, 2nd, 3rd, and 4th years of follow-up. Gastric sleeve (GS) surgery was associated with higher prediabetes remission rate than Roux-en-Y gastric bypass surgery in the 3rd year of follow-up. Men had a higher remission rate than women, in the 1st and 3nd years of follow-up in the unadjusted analysis. Younger patients presented a higher remission rate comparing to older patients in the 3rd year of follow-up.
Conclusion
We showed a high prediabetes remission rate after bariatric surgery. The remission rate decreases over the follow-up period, although most of the patients maintain the normoglycemia. Prediabetes remission seems to be more significant in patients who had undergone GS, in male and in younger patients.
Journal Article
Psychological and Behavioral Aspects of Primary and Reoperative Surgery: a 6-Month Longitudinal Study
by
Pinto-Bastos, Ana
,
Arrojado, Filipa
,
Marta de Lourdes
in
Anxiety
,
Eating disorders
,
Gastrointestinal surgery
2018
BackgroundProblematic eating behaviors and general psychopathology have been associated with poor weight loss after bariatric surgery. However, little is known about how these aspects impact weight loss outcomes for the increasing number of patients undergoing reoperative surgeries. This study compares disordered eating and weight-related outcomes before and 6 months after surgery in patients undergoing primary (P-Group) and reoperative bariatric surgery (R-Group).MethodsThis longitudinal study assessed 122 P-Group and 116 R-Group patients before and 6 months after surgery. The assessment included the eating disorder examination diagnostic items, and a set of self-report measures assessing eating disorder symptomatology, grazing, depression, anxiety, and negative urgency.ResultsPreoperatively, no differences were found between the R- and P-Groups in terms of disordered eating-related variables (except for shape concern, which was higher for the R-Group). At 6 months after surgery, the R-Group revealed significantly higher values for restraint (F(1,219) = 5.84, p = 0.016), shape (F(1,219) = 5.59, p = 0.019), weight concerns (F(1,219) = 13.36, p = 0.000), depression (F(1,219) = 7.17, p = 0.008), anxiety (F(1,219) = 6.94, p = − 0.009), and compulsive grazing (F(1,219) = 6.13, p = 0.014). No significant pre- or post-surgery predictors of weight loss were found for the P-Group (χ2 = 0.70, p = 0.872). In the R-Group, post-surgery anxiety (Waldχ2(1) = 6.19, p = 0.01) and the post-surgery number of days with grazing in the previous month (Waldχ2(1) = 3.90, p = 0.04) were significant predictors of weight loss.ConclusionAt 6 months after surgery, the R-Group presented more problematic eating and general psychological distress, which may put these patients at greater risk of poorer long-term weight outcomes.
Journal Article
Adult attachment in eating disorders mediates the association between perceived invalidating childhood environments and eating psychopathology
by
Gonçalves, Sónia
,
Machado, Bárbara
,
Timóteo, Sertório
in
Attachment
,
Behavioral Science and Psychology
,
Eating disorders
2021
This study aimed to evaluate the associations between perceived invalidating childhood environments, attachment in intimate relationships and eating psychopathology, to explore how these variables interact with each other, and to explore potential mediators to this pattern of association in a clinical eating disorder (ED) sample. One hundred thirty-seven ED outpatients were evaluated with the Invalidating Childhood Environments Scale (ICES), the Eating Disorder-15 (ED-15) and the Experiences in Close Relationships Inventory (ECR). Paternal invalidation was associated to the ED-15 total score through avoidance of proximity and anxiety over abandonment, while maternal invalidation was only associated to the ED-15 total score through avoidance of proximity. Our results highlight the potential role of the perception of an invalidating family environment in the development of eating pathology and of difficulties in intimate relationships. These results endorse the relevance of address parental invalidation and promote adequate emotion regulation strategies and interpersonal competencies in the context of intimate relationships.
Journal Article
Impact of Depression on Weight Variation after Bariatric Surgery: A Three-Year Observational Study
by
Carvalho, Davide
,
Mendonça, Fernando
,
Brandão, Isabel
in
bariatric surgery
,
Blood pressure
,
Confounding (Statistics)
2020
Introduction: The association between obesity and depression has been repeatedly established. However, little is known about the impact that the diagnosis of depression before bariatric surgery (DDBS) may have on weight loss. Objective: To evaluate the impact of DDBS on weight outcomes. Methods: Retrospective study of patients submitted to BS. Patients with no weight, no current medication data, or those submitted to revision surgery were excluded. Patients were considered to have DDBS based on taking antidepressants prior to BS or if there was a medical history of past or current depression. Patients with and without a depression history were compared using independent t test. A multivariate logistic regression model was created to evaluate predictors of weight variation (variables included: age, sex, and type of surgery). Results: A total of 616 patients did not have a history of depression and 230 had DDBS. There was a statistically significant difference in the BMI variation between groups. On average, individuals with DDBS lost 1.4 kg/m 2 less than those without DDBS. In the multivariate analysis, the group with DDBS, compared with the group without DDBS, presented on average less –0.9 kg/m 2 (95% CI –1.7 to –0.2, p = 0.018) BMI variation. Conclusion: DDBS is a predictor of lower weight loss after the surgical procedure. Even after adjusting for confounding variables such as age, sex, and BS type, this effect remains.
Journal Article