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How to rig an election
An engrossing analysis of the pseudo-democratic methods employed by despots around the world to retain control Contrary to what is commonly believed, authoritarian leaders who agree to hold elections are generally able to remain in power longer than autocrats who refuse to allow the populace to vote. In this engaging and provocative book, Nic Cheeseman and Brian Klaas expose the limitations of national elections as a means of promoting democratization, and reveal the six essential strategies that dictators use to undermine the electoral process in order to guarantee victory for themselves. Based on their firsthand experiences as election watchers and their hundreds of interviews with presidents, prime ministers, diplomats, election officials, and conspirators, Cheeseman and Klaas document instances of election rigging from Argentina to Zimbabwe, including notable examples from Brazil, India, Nigeria, Russia, and the United States-touching on the 2016 election. This eye-opening study offers a sobering overview of corrupted professional politics, while providing fertile intellectual ground for the development of new solutions for protecting democracy from authoritarian subversion.
eBook
Trouble no man : a novel
\"The story of one man's struggle to survive a hostile world, tracing his path from a self-destructive, skateboarding youth in the 90s to the near future as he journeys across a desolate, militia-controlled American West to find his missing family.\"
Book
Handbook of Compliant Mechanisms
A fully illustrated reference book giving an easy-to-understand introduction to compliant mechanisms A broad compilation of compliant mechanisms to give inspiration and guidance to those interested in using compliant mechanisms in their designs, the Handbook of Compliant Mechanisms includes graphics and descriptions of many compliant mechanisms. It comprises an extensive categorization of devices that can be used to help readers identify compliant mechanisms related to their application. It also provides chapters on the basic background in compliant mechanisms, the categories of compliant mechanisms, and an example of how the Compendium can be used to facilitate compliant mechanism design. * Fully illustrated throughout to be easily understood and accessible at introductory levels * Covers all aspects pertaining to classification, elements, mechanisms and applications of compliant mechanisms * Summarizes a vast body of knowledge in easily understood diagrams and explanations * Helps readers appreciate the advantages that compliant mechanisms have to offer * Practical approach is ideal for potential practitioners who would like to realize designs with compliant mechanisms, members and elements * Breadth of topics covered also makes the book a useful reference for more advanced readers Intended as an introduction to the area, the Handbook avoids technical jargon to assist non engineers involved in product design, inventors and engineers in finding clever solutions to problems of design and function.
eBook
Bones and cartilage : developmental and evolutionary skeletal biology
Bones and Cartilage provides the most in-depth review ever assembled on the topic. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage is developed in embryos and are maintained in adults, how bone reappears when we break a leg, or even regenerates when a newt grows a new limb, or a lizard a tail. This book also looks at the molecules and cells that make bones and cartilages and how they differ in various parts of the body and across species. It answers such questions as \"Is bone always bone?\" \"Do bones that develop indirectly by replacing other tissues, such as marrow, tendons or ligaments, differ from one another?\" \"Is fish bone the same as human bone?\" \"Can sharks even make bone?\" and many more. * Complete coverage of every aspect of bone and cartilage* Full of interesting and unusual facts* The only book available that integrates development and evolution of the skeleton* Treats all levels from molecular to clinical, embryos to evolution* Written in a lively, accessible style* Extensively illustrated and referenced* Integrates analysis of differentiation, growth and patterning* Covers all the vertebrates as well as invertebrate cartilages* Identifies the stem cells in embryos and adults that can make skeletal tissues
eBook
Probability, random processes, and statistical analysis
Together with the fundamentals of probability, random processes and statistical analysis, this insightful book also presents a broad range of advanced topics and applications. There is extensive coverage of Bayesian vs. frequentist statistics, time series and spectral representation, inequalities, bound and approximation, maximum-likelihood estimation and the expectation-maximization (EM) algorithm, geometric Brownian motion and Ito process. Applications such as hidden Markov models (HMM), the Viterbi, BCJR, and Baum-Welch algorithms, algorithms for machine learning, Wiener and Kalman filters, and queueing and loss networks are treated in detail. The book will be useful to students and researchers in such areas as communications, signal processing, networks, machine learning, bioinformatics, econometrics and mathematical finance. With a solutions manual, lecture slides, supplementary materials and MATLAB programs all available online, it is ideal for classroom teaching as well as a valuable reference for professionals.
eBook
Rwanda
Culture smart! Rwanda is an illuminating and practical guide to Rwanda's culture and society. It will help you turn your visit -- whether it's for business or for pleasure -- into a memorable and enriching experience. Contents include: local customs and traditions, the impact of history, religion, and politics, the Rwandans at home, work, and play, eating and drinking, Rwandan style, dos, don'ts, and taboos, business practices, and communication, spoken and unspoken and many practical tips for managing the unexpected.
Book
Structure, function and pharmacology of human itch GPCRs
The MRGPRX family of receptors (MRGPRX1–4) is a family of mas-related G-protein-coupled receptors that have evolved relatively recently
1
. Of these, MRGPRX2 and MRGPRX4 are key physiological and pathological mediators of itch and related mast cell-mediated hypersensitivity reactions
2
–
5
. MRGPRX2 couples to both G
i
and G
q
in mast cells
6
. Here we describe agonist-stabilized structures of MRGPRX2 coupled to G
i1
and G
q
in ternary complexes with the endogenous peptide cortistatin-14 and with a synthetic agonist probe, respectively, and the development of potent antagonist probes for MRGPRX2. We also describe a specific MRGPRX4 agonist and the structure of this agonist in a complex with MRGPRX4 and G
q
. Together, these findings should accelerate the structure-guided discovery of therapeutic agents for pain, itch and mast cell-mediated hypersensitivity.
Structural studies of the itch receptors MRGPRX2 and MRGPRX4 in complex with endogenous and synthetic ligands provide a basis for the development of therapeutic compounds for pain, itch and mast cell-mediated hypersensitivity.
Journal Article