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"Brown, Andrea"
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Assessment in art therapy
\"Assessment in Art Therapy gives a unique insight into the diverse contemporary practices that constitute assessment in art therapy, providing an overview of the different approaches employed in Britain and America today. This professional handbook comprises three main sections. Sitting beside explores the discursive and the relational in art therapy assessments with adults and children in different settings. Snapshots from the field presents a series of short, practice-based reports which describe art therapists working in private practice, secure settings and community mental health centres. A more distant calculation consists of chapters that describe the development and use of different kinds of art-based assessment procedures developed on both sides of the Atlantic, as well as different kinds of research about art therapy assessment. Both students and practitioners alike will benefit from the wealth of experience presented in this book, which demonstrates how art therapists think about assessment; the difficulties that arise in art therapy assessment and the importance of developing the theory and practice of art therapy assessment, whilst taking into account the changing demands of systems and institutions\"-- Provided by publisher.
Book
A multidimensional selective landscape drives adaptive divergence between and within closely related Phlox species
Selection causes local adaptation across populations within species and simultaneously divergence between species. However, it is unclear if either the force of or the response to selection is similar across these scales. We show that natural selection drives divergence between closely related species in a pattern that is distinct from local adaptation within species. We use reciprocal transplant experiments across three species of
Phlox
wildflowers to characterize widespread adaptive divergence. Using provenance trials, we also find strong local adaptation between populations within a species. Comparing divergence and selection between these two scales of diversity we discover that one suite of traits predicts fitness differences between species and that an independent suite of traits predicts fitness variation within species. Selection drives divergence between species, contributing to speciation, while simultaneously favoring extensive diversity that is maintained across populations within a species. Our work demonstrates how the selection landscape is complex and multidimensional.
Selection drives divergence between species, contributing to speciation, while simultaneously favoring extensive diversity that is maintained across populations within a species. This study demonstrates how the selection landscape is complex and multidimensional across three species of Phlox flowers.
Journal Article
Avengers Academy : the complete collection. Vol. 2
The Avengers Academy faces Fear Itself! No, not prom night - though they have to survive that too, when the Sinister Six crash the party! We mean actual Fear Itself, as the Serpent's army assaults the Marvel Universe and the squad must battle the possessed, hammer-wielding versions of Titania and the Absorbing Man! Meanwhile, as Speedball returns to the scene of his greatest failure, can he rally the town of Stamford against the Serpent and finally earn forgiveness from its people - or himself? Plus, the students get schooled by a substitute teacher - the Amazing Spider-Man - but their lesson is interrupted by Psycho-Man! And as Hank Pym relocates the Academy to California, they come under attack by...the West Coast Avengers?!
Book
30×30 biodiversity gains rely on national coordination
Global commitments to protect 30% of land by 2030 present an opportunity to combat the biodiversity crisis, but reducing extinction risk will depend on where countries expand protection. Here, we explore a range of 30×30 conservation scenarios that vary what dimension of biodiversity is prioritized (taxonomic groups, species-at-risk, biodiversity facets) and how protection is coordinated (transnational, national, or regional approaches) to test which decisions influence our ability to capture biodiversity in spatial planning. Using Canada as a model nation, we evaluate how well each scenario captures biodiversity using scalable indicators while accounting for climate change, data bias, and uncertainty. We find that only 15% of all terrestrial vertebrates, plants, and butterflies (representing only 6.6% of species-at-risk) are adequately represented in existing protected land. However, a nationally coordinated approach to 30×30 could protect 65% of all species representing 40% of all species-at-risk. How protection is coordinated has the largest impact, with regional approaches protecting up to 38% fewer species and 65% fewer species-at-risk, while the choice of biodiversity incurs much smaller trade-offs. These results demonstrate the potential of 30×30 while highlighting the critical importance of biodiversity-informed national strategies.
Expanding protected areas to meet conservation goals requires careful consideration of potential trade-offs. Here, by simulating conservation scenarios for Canada, the authors report that 30×30 outcomes for biodiversity depend more on how protection is coordinated at different spatial scales than on which biodiversity metrics are prioritized.
Journal Article
catalytic beacon sensor for uranium with parts-per-trillion sensitivity and millionfold selectivity
Here, we report a catalytic beacon sensor for uranyl (UO[Formula: see text]) based on an in vitro-selected UO[Formula: see text]-specific DNAzyme. The sensor consists of a DNA enzyme strand with a 3' quencher and a DNA substrate with a ribonucleotide adenosine (rA) in the middle and a fluorophore and a quencher at the 5' and 3' ends, respectively. The presence of UO[Formula: see text] causes catalytic cleavage of the DNA substrate strand at the rA position and release of the fluorophore and thus dramatic increase of fluorescence intensity. The sensor has a detection limit of 11 parts per trillion (45 pM), a dynamic range up to 400 nM, and selectivity of >1-million-fold over other metal ions. The most interfering metal ion, Th(IV), interacts with the fluorescein fluorophore, causing slightly enhanced fluorescence intensity, with an apparent dissociation constant of [almost equal to]230 μM. This sensor rivals the most sensitive analytical instruments for uranium detection, and its application in detecting uranium in contaminated soil samples is also demonstrated. This work shows that simple, cost-effective, and portable metal sensors can be obtained with similar sensitivity and selectivity as much more expensive and sophisticated analytical instruments. Such a sensor will play an important role in environmental remediation of radionuclides such as uranium.
Journal Article
Distinct Transcript Isoforms of the Atypical Chemokine Receptor 1 (ACKR1) / Duffy Antigen Receptor for Chemokines (DARC) Gene Are Expressed in Lymphoblasts and Altered Isoform Levels Are Associated with Genetic Ancestry and the Duffy-Null Allele
The Atypical ChemoKine Receptor 1 (ACKR1) gene, better known as Duffy Antigen Receptor for Chemokines (DARC or Duffy), is responsible for the Duffy Blood Group and plays a major role in regulating the circulating homeostatic levels of pro-inflammatory chemokines. Previous studies have shown that one common variant, the Duffy Null (Fy-) allele that is specific to African Ancestry groups, completely removes expression of the gene on erythrocytes; however, these individuals retain endothelial expression. Additional alleles are associated with a myriad of clinical outcomes related to immune responses and inflammation. In addition to allele variants, there are two distinct transcript isoforms of DARC which are expressed from separate promoters, and very little is known about the distinct transcriptional regulation or the distinct functionality of these protein isoforms. Our objective was to determine if the African specific Fy- allele alters the expression pattern of DARC isoforms and therefore could potentially result in a unique signature of the gene products, commonly referred to as antigens. Our work is the first to establish that there is expression of DARC on lymphoblasts. Our data indicates that people of African ancestry have distinct relative levels of DARC isoforms expressed in these cells. We conclude that the expression of both isoforms in combination with alternate alleles yields multiple Duffy antigens in ancestry groups, depending upon the haplotypes across the gene. Importantly, we hypothesize that DARC isoform expression patterns will translate into ancestry-specific inflammatory responses that are correlated with the axis of pro-inflammatory chemokine levels and distinct isoform-specific interactions with these chemokines. Ultimately, this work will increase knowledge of biological mechanisms underlying disparate clinical outcomes of inflammatory-related diseases among ethnic and geographic ancestry groups.
Journal Article
Results of a Competency-Based Approach to Prepare General Educators to Effectively Include Students with Disabilities
Research has shown that general educators may lack the competencies to effectively include students with disabilities, thus widening the gaps in outcomes between students with disabilities and their peers. In this study, we outline the development and implementation of a competency-based continuing education program, designed to equip general educators to effectively include students with disabilities (SWDs) and earn special education certification. This paper presents the results of a program evaluation conducted using both validated measures and author-developed instruments. Participants included general education teachers, instructional coaches, and those in similar roles. Results indicated that participants significantly increased their knowledge of professional standards, demonstrated knowledge in high-leverage practices, and showed high levels of self-efficacy to implement inclusive practices. We discuss these results, emphasizing the timeliness of this nontraditional approach and its implications for teacher preparation, research, and policy amid the troubling national special education teacher shortage. Namely, this approach epitomizes a model that allows leaders to strategically utilize their existing workforce to address vacancies in special education and emphasizes that the responsibility to support SWDs rests squarely upon all educators.
Journal Article
Artificial Intelligence in Special Education
This entry examines the growing role of artificial intelligence (AI) in special education. The authors discuss applications of AI in the field, including its uses for personalized learning, adaptive technologies, teacher support, and AI’s potential to address issues related to student accessibility and engagement. The entry draws on recent syntheses of literature, highlighting studies that reveal AI’s capacity to improve educational outcomes for students with disabilities, mitigate teacher workload, and foster inclusion. Despite these promising developments, the authors address ethical considerations, potential biases, and privacy concerns surrounding the use of AI, as well as the need for high-quality research that validates AI’s effectiveness in special education. The authors conclude that while AI can offer substantial support, it should be integrated thoughtfully, guided by empirical research, and accompanied by skilled professional oversight to ensure that it truly benefits students with disabilities.
Journal Article