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"Brown, Anne"
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Three revolutions : steering automated, shared, and electric vehicles to a better future
For the first time in half a century, real transformative innovations are coming to our world of passenger transportation.The convergence of new shared mobility services with automated and electric vehicles promises to significantly reshape our lives and communities for the better--or for the worse.
eBook
Living with Jim Crow : African American women and memories of the segregated South
\"This groundbreaking book collects black women's personal recollections of their public and private lives during the period of legal segregation in the American South. Using first-person narratives, collected through oral history interviews, the book emphasizes women's role in their families and communities, treating women as important actors in the economic, social, cultural, and political life of the segregated South. By focusing on the commonalities of women's experiences, as well as the ways that women's lives differed from the experiences of southern black men, Living with Jim Crow analyzes the interlocking forces of racism and sexism\"--Provided by publisher.
Book
The spatial turn, reification and relational epistemologies in ‘knowing about’ security and peace
How we approach knowing conflict and security makes a difference. This article first considers how reification, instrumental subject/object relations and the drive for certainty and control undermine effective knowledge and practice in questions of conflict and peace. It then turns to what the spatial turn and notions of emplaced security might offer to working against violence. As with any theoretical perspective, the spatial turn can itself be reified, repeating epistemological relations entrenched in much security analysis. The spatial turn and emplaced security explicitly highlight alternative, more relational knowledge practices, however. A relational epistemology approaches knowledge not only as information about a subject out there, but also as a form of practice with others which changes conditions of possibility for co-existence. If pursued, such approaches could help loosen the grip of narrow constructions of security, insecurity, the person, power and agency which dominate security analysis and obstruct understanding and the generation of alternatives in situations of entrenched conflict. An orientation to place could not only enable more nuanced accounts of peace and conflict, but support mutual recognition and exchange across division, assisting an ethic of attention and concrete peace and conflict resolution efforts.
Journal Article
Widespread exposure to SARS-CoV-2 in wildlife communities
Pervasive SARS-CoV-2 infections in humans have led to multiple transmission events to animals. While SARS-CoV-2 has a potential broad wildlife host range, most documented infections have been in captive animals and a single wildlife species, the white-tailed deer. The full extent of SARS-CoV-2 exposure among wildlife communities and the factors that influence wildlife transmission risk remain unknown. We sampled 23 species of wildlife for SARS-CoV-2 and examined the effects of urbanization and human use on seropositivity. Here, we document positive detections of SARS-CoV-2 RNA in six species, including the deer mouse, Virginia opossum, raccoon, groundhog, Eastern cottontail, and Eastern red bat between May 2022–September 2023 across Virginia and Washington, D.C., USA. In addition, we found that sites with high human activity had three times higher seroprevalence than low human-use areas. We obtained SARS-CoV-2 genomic sequences from nine individuals of six species which were assigned to seven Pango lineages of the Omicron variant. The close match to variants circulating in humans at the time suggests at least seven recent human-to-animal transmission events. Our data support that exposure to SARS-CoV-2 has been widespread in wildlife communities and suggests that areas with high human activity may serve as points of contact for cross-species transmission.
The wildlife host range of SARS-CoV-2 is currently unknown. Here, the authors report evidence of infection in six common wild animal species (deer mouse, Virginia opossum, raccoon, groundhog, Eastern cottontail, Eastern red bat) out of 23 species tested in Virginia and Washington DC, USA in 2022/2023.
Journal Article
Genome-wide associations and epistatic interactions for internode number, plant height, seed weight and seed yield in soybean
Background
Breeding programs benefit from information about marker-trait associations for many traits, whether the goal is to place those traits under active selection or to maintain them through background selection. Association studies are also important for identifying accessions bearing potentially useful alleles by characterizing marker-trait associations and allelic states across germplasm collections. This study reports the results of a genome-wide association study and evaluation of epistatic interactions for four agronomic and seed-related traits in soybean.
Results
Using 419 diverse soybean accessions, together with genotyping data from the SoySNP50K Illumina Infinium BeadChip, we identified marker-trait associations for internode number (IN), plant height (PH), seed weight (SW), and seed yield per plant (SYP). We conducted a genome-wide epistatic study (GWES), identifying candidate genes that show evidence of SNP-SNP interactions. Although these candidate genes will require further experimental validation, several appear to be involved in developmental processes related to the respective traits. For IN and PH, these include the Dt1 determinacy locus (a soybean meristematic transcription factor), as well as a pectinesterase gene and a squamosa promoter binding gene that in other plants are involved in cell elongation and the vegetative-to-reproductive transition, respectively. For SW, candidate genes include an ortholog of the AP2 gene, which in other species is involved in maintaining seed size, embryo size, seed weight and seed yield. Another SW candidate gene is a histidine phosphotransfer protein - orthologs of which are involved in cytokinin-mediated seed weight regulating pathways. The SYP association loci overlap with regions reported in previous QTL studies to be involved in seed yield.
Conclusions
This study further confirms the utility of GWAS and GWES approaches for identifying marker-trait associations and interactions within a diverse germplasm collection.
Journal Article
A review of breeding objectives, genomic resources, and marker-assisted methods in common bean (Phaseolus vulgaris L.)
Common bean (
Phaseolus vulgaris
L.), one of the most important grain legume crops for direct human consumption, faces many challenges as a crop. Domesticated from wild relatives that inhabit a relatively narrow ecological niche, common bean faces a wide range of biotic and abiotic constraints within its diverse agroecological settings. Biotic stresses impacting common bean include numerous bacterial, fungal, and viral diseases and various insect and nematode pests, and abiotic stresses include drought, heat, cold, and soil nutrient deficiencies or toxicities. Breeding is often local, focusing on improvements in responses to biotic and abiotic stresses that are particular challenges in certain locations and needing to respond to conditions such as day-length regimes. This review describes the major breeding objectives for common bean, followed by a description of major genetic and genomic resources, and an overview of current and prospective marker-assisted methods in common bean breeding. Improvements over traditional breeding methods in CB can result from the use of different approaches. Several important germplasm collections have been densely genotyped, and relatively inexpensive SNP genotyping platforms enable implementation of genomic selection and related marker-assisted breeding approaches. Also important are sociological insights related to demand-led breeding, which considers local value chains, from farmers to traders to retailers and consumers.
Journal Article