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result(s) for
"Brown, Stephanie"
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The case of the disappearing Gauguin : a study of authenticity and the art market
by
Brown, Stephanie (Stephanie A.), author
in
Gauguin, Paul, 1848-1903 Authorship.
,
Painting Expertising.
,
Painting Economic aspects.
2024
\"Authentic or forged? Follow the journey of a painting that may (or may not) be the work of Paul Gauguin as it travels around the world over the course of a century. Explore the networks and relationships that help determine authenticity in the art world\"-- Provided by publisher.
Tidal Deformability of Neutron Stars in Scalar-tensor Theories of Gravity
2023
Gravitational waves from compact binary coalescences are valuable for testing theories of gravity in the strong field regime. By measuring neutron star tidal deformability using gravitational waves from binary neutron stars, stringent constraints were placed on the equation of state of matter at extreme densities. Tidal Love numbers in alternative theories of gravity may differ significantly from their general relativistic counterparts. Understanding exactly how the tidal Love numbers change will enable scientists to untangle physics beyond general relativity from the uncertainty in the equation of state measurement. In this work, we explicitly calculate the fully relativistic l ≥ 2 tidal Love numbers for neutron stars in scalar-tensor theories of gravitation. We use several realistic equations of state to explore how the mass, radius, and tidal deformability relations differ from those of general relativity. We find that tidal Love numbers and tidal deformabilities can differ significantly from those in general relativity in certain regimes. The electric tidal deformability can differ by ∼200%, and the magnetic tidal deformability differs by ∼300%. These deviations occur at large compactnesses (C = M/r ≳ 0.2) and vary slightly depending on the equation of state. This difference suggests that using the tidal Love numbers from general relativity could lead to significant errors in tests of general relativity using the gravitational waves from binary neutron star and neutron star black hole mergers.
Journal Article
Stringent constraints on neutron-star radii from multimessenger observations and nuclear theory
by
Brown, Stephanie M.
,
Capano, Collin D.
,
Tews, Ingo
in
639/766/34/4118
,
639/766/34/4123
,
639/766/387/1127
2020
The properties of neutron stars are determined by the nature of the matter that they contain. These properties can be constrained by measurements of the star’s size. We obtain stringent constraints on neutron-star radii by combining multimessenger observations of the binary neutron-star merger GW170817 with nuclear theory that best accounts for density-dependent uncertainties in the equation of state. We construct equations of state constrained by chiral effective field theory and marginalize over these using the gravitational-wave observations. Combining this with the electromagnetic observations of the merger remnant that imply the presence of a short-lived hypermassive neutron star, we find that the radius of a 1.4
M
⊙
neutron star is
R
1.4
M
⊙
=
11.0
−
0.6
+
0.9
km
(90% credible interval). Using this constraint, we show that neutron stars are unlikely to be disrupted in neutron star–black hole mergers; subsequently, such events will not produce observable electromagnetic emission.
The combination of electromagnetic and gravitational-wave observations of binary neutron-star merger GW170817 with systematic sets of neutron-star equations of state has produced a tightly constrained radius of 11 km for a 1.4
M
⊙
neutron star. This constraint suggests that a neutron star–black hole merger is unlikely to produce an electromagnetic counterpart.
Journal Article
Common maternal health problems among Australian-born and migrant women: A prospective cohort study
2019
Migrant women of non-English speaking background make up an increasing proportion of women giving birth in high income countries, such as Australia, Canada and the United Kingdom. The aim of this study was to assess the prevalence of common physical and psychosocial health problems during pregnancy and up to 18 months postpartum among migrant women of non-English speaking background compared to Australian-born women.
Prospective pregnancy cohort study of 1507 nulliparous women. Women completed self-administered questionnaires or telephone interviews in early and late pregnancy and at 3, 6, 9, 12 and 18 months postpartum. Standardised instruments were used to assess incontinence, depressive symptoms and intimate partner violence.
Migrant women of non-English speaking background (n = 243) and Australian-born mothers (n = 1115) reported a similar pattern of physical health problems during pregnancy and postpartum. The most common physical health problems were: exhaustion, back pain, constipation and urinary incontinence. Around one in six Australian-born women (16.9%) and more than one in four migrant women (22.5%) experienced intimate partner abuse in the first 12 months postpartum. Compared to Australian-born women, migrant women were more likely to report depressive symptoms at 12 and 18 months postpartum.
Physical and mental health problems are common among women of non-English speaking background and Australian-born women, and frequently persist up to 18 months postpartum. Migrant women experience a higher burden of postpartum depressive symptoms and intimate partner violence, and may face additional challenges accessing appropriate care and support.
Journal Article
De novo production of the plant-derived alkaloid strictosidine in yeast
by
Clastre, Marc
,
Brown, Stephanie
,
Courdavault, Vincent
in
Alcohol Dehydrogenase - metabolism
,
antineoplastic agents
,
bioactive properties
2015
The monoterpene indole alkaloids are a large group of plant-derived specialized metabolites, many of which have valuable pharmaceutical or biological activity. There are ∼3,000 monoterpene indole alkaloids produced by thousands of plant species in numerous families. The diverse chemical structures found in this metabolite class originate from strictosidine, which is the last common biosynthetic intermediate for all monoterpene indole alkaloid enzymatic pathways. Reconstitution of biosynthetic pathways in a heterologous host is a promising strategy for rapid and inexpensive production of complex molecules that are found in plants. Here, we demonstrate how strictosidine can be produced de novo in aSaccharomyces cerevisiaehost from 14 known monoterpene indole alkaloid pathway genes, along with an additional seven genes and three gene deletions that enhance secondary metabolism. This system provides an important resource for developing the production of more complex plant-derived alkaloids, engineering of nonnatural derivatives, identification of bottlenecks in monoterpene indole alkaloid biosynthesis, and discovery of new pathway genes in a convenient yeast host.
Journal Article
Using Gravitational Waves to Distinguish between Neutron Stars and Black Holes in Compact Binary Mergers
by
Krishnan, Badri
,
Capano, Collin D
,
Brown, Stephanie M
in
Binary stars
,
Black holes
,
Field theory
2022
In 2017 August, the first detection of a binary neutron star merger, GW170817, made it possible to study neutron stars in compact binary systems using gravitational waves. Despite being the loudest gravitational-wave event detected to date (in terms of signal-to-noise ratio), it was not possible to unequivocally determine that GW170817 was caused by the merger of two neutron stars instead of two black holes from the gravitational-wave data alone. That distinction was primarily due to the accompanying electromagnetic counterpart. This raises the question: under what circumstances can gravitational-wave data alone, in the absence of an electromagnetic signal, be used to distinguish between different types of mergers? Here, we study whether a neutron star–black hole binary merger can be distinguished from a binary black hole merger using gravitational-wave data alone. We build on earlier results using chiral effective field theory to explore whether the data from LIGO and Virgo, LIGO A+, LIGO Voyager, the Einstein Telescope, or Cosmic Explorer could lead to such a distinction. The results suggest that the present LIGO–Virgo detector network will most likely be unable to distinguish between these systems even with the planned near-term upgrades. However, given an event with favorable parameters, third-generation instruments such as Cosmic Explorer will be capable of making this distinction. This result further strengthens the science case for third-generation detectors.
Journal Article
Postpartum anxiety, depression and social health: findings from a population-based survey of Australian women
2010
Background
Whilst the prevalence and correlates of postpartum depression are well established, far less is known about postpartum anxiety. Studies have described the association between socio-demographic factors and postpartum depression, yet few have explored the association between stressors in women's lives around the time of having a baby and maternal psychological morbidity. This study aimed to describe the population prevalence of postpartum depression, anxiety, co-morbid anxiety and depression and social health issues; and to examine the association between postpartum psychological and social health issues experienced in the six months following birth.
Methods
Population-based survey of all women who gave birth in Victoria and South Australia in September/October 2007. Women were mailed the survey questionnaire six months following birth. Anxiety and depression were measured using the Depression Anxiety Stress Scales (DASS-21).
Results
Questionnaires were completed by 4,366 women. At six months postpartum the proportion of women scoring above the 'normal' range on the DASS-21 was 12.7% for anxiety,17.4% for depression, and 8.1% for co-morbid depression and anxiety. Nearly half the sample reported experiencing stressful life events or social health issues in the six months following birth, with 38.3% reporting one to two and 8.8% reporting three or more social health issues. Women reporting three or more social health issues were significantly more likely to experience postnatal anxiety (Adj OR = 4.12, 95% CI 3.0-5.5) or depression (Adj OR = 5.11, 95% CI = 3.9-6.7) and co-morbid anxiety
and
depression (Adj OR = 5.41, 95% CI 3.8-7.6) than women who did not report social health issues.
Conclusions
Health care providers including midwives, nurses, medical practitioners and community health workers need to be alert to women's social circumstances and life events experienced in the perinatal period and the interplay between social and emotional health. Usual management for postpartum mental health issues including Cognitive Behavioural Therapy and pharmacological approaches may not be effective if social health issues are not addressed. Coordinated and integrated perinatal care that is responsive to women's social health may lead to improvements in women's emotional wellbeing following birth.
Journal Article