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The author's thoughts and opinions on where the field of forensic DNA testing is headed for the next decade are provided in the context of where the field has come over the past 30 years. Similar to the Olympic motto of ‘faster, higher, stronger’, forensic DNA protocols can be expected to become more rapid and sensitive and provide stronger investigative potential. New short tandem repeat (STR) loci have expanded the core set of genetic markers used for human identification in Europe and the USA. Rapid DNA testing is on the verge of enabling new applications. Next-generation sequencing has the potential to provide greater depth of coverage for information on STR alleles. Familial DNA searching has expanded capabilities of DNA databases in parts of the world where it is allowed. Challenges and opportunities that will impact the future of forensic DNA are explored including the need for education and training to improve interpretation of complex DNA profiles.

A little, newborn lamb, too shy to say hello to the rabbit or sing with the robin, is finally drawn out by a tiny fieldmouse.

Intended as a companion to the Fundamentals of Forensic DNA Typing volume published in 2009, Advanced Topics in Forensic DNA Typing: Methodology contains 18 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field and citation to more than 2800 articles and internet resources. The book builds upon the previous two editions of John Butler's internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience.  This book provides the most detailed information written to-date on DNA databases, low-level DNA, validation, and numerous other topics including a new chapter on legal aspects of DNA testing to prepare scientists for expert witness testimony. Over half of the content is new compared to previous editions. A forthcoming companion volume will cover interpretation issues. Contains the latest information - hot-topics and new technologiesWell edited, attractively laid out, and makes productive use of its four-color formatAuthor John Butler is ranked as the number one \"high-impact author in legal medicine and forensic science, 2001 to 2011\" by ScienceWatch.com

Anju the Asian elephant recalls her childhood in Sumatra, and the American circuses and zoos in which she toiled for fifty years, when she is loaded into a trailer truck and taken to a sanctuary. Includes advice on helping elephants and \"Elephant Q&A\".

Population-based cancer survival estimates provide valuable insights into the effectiveness of cancer services and can reflect the prospects of cure. As part of the second phase of the International Cancer Benchmarking Partnership (ICBP), the Cancer Survival in High-Income Countries (SURVMARK-2) project aims to provide a comprehensive overview of cancer survival across seven high-income countries and a comparative assessment of corresponding incidence and mortality trends. In this longitudinal, population-based study, we collected patient-level data on 3·9 million patients with cancer from population-based cancer registries in 21 jurisdictions in seven countries (Australia, Canada, Denmark, Ireland, New Zealand, Norway, and the UK) for seven sites of cancer (oesophagus, stomach, colon, rectum, pancreas, lung, and ovary) diagnosed between 1995 and 2014, and followed up until Dec 31, 2015. We calculated age-standardised net survival at 1 year and 5 years after diagnosis by site, age group, and period of diagnosis. We mapped changes in incidence and mortality to changes in survival to assess progress in cancer control. In 19 eligible jurisdictions, 3 764 543 cases of cancer were eligible for inclusion in the study. In the 19 included jurisdictions, over 1995–2014, 1-year and 5-year net survival increased in each country across almost all cancer types, with, for example, 5-year rectal cancer survival increasing more than 13 percentage points in Denmark, Ireland, and the UK. For 2010–14, survival was generally higher in Australia, Canada, and Norway than in New Zealand, Denmark, Ireland, and the UK. Over the study period, larger survival improvements were observed for patients younger than 75 years at diagnosis than those aged 75 years and older, and notably for cancers with a poor prognosis (ie, oesophagus, stomach, pancreas, and lung). Progress in cancer control (ie, increased survival, decreased mortality and incidence) over the study period was evident for stomach, colon, lung (in males), and ovarian cancer. The joint evaluation of trends in incidence, mortality, and survival indicated progress in four of the seven studied cancers. Cancer survival continues to increase across high-income countries; however, international disparities persist. While truly valid comparisons require differences in registration practice, classification, and coding to be minimal, stage of disease at diagnosis, timely access to effective treatment, and the extent of comorbidity are likely the main determinants of patient outcomes. Future studies are needed to assess the impact of these factors to further our understanding of international disparities in cancer survival. Canadian Partnership Against Cancer; Cancer Council Victoria; Cancer Institute New South Wales; Cancer Research UK; Danish Cancer Society; National Cancer Registry Ireland; The Cancer Society of New Zealand; National Health Service England; Norwegian Cancer Society; Public Health Agency Northern Ireland, on behalf of the Northern Ireland Cancer Registry; The Scottish Government; Western Australia Department of Health; and Wales Cancer Network.

\"SEQUEL TO WITCHY EYE. Next in series, which debuted with the stunningly reviewed Witchy Eye. Butler delivers another brilliant Americana flintlock fantasy novel. TOIL AND TROUBLE Sarah Calhoun paid a hard price for her entry onto the stage of the Empire's politics, but she survived. Now she rides north into the Ohio and her father's kingdom, Cahokia. To win the Serpent Throne, she'll have to defeat seven other candidates, win over the kingdom's regent, and learn the will of a hidden goddess--while mastering her people's inscrutable ways and watching her own back. In New Orleans, a new and unorthodox priest arises to plague the chevalier and embody the curse of the murdered Bishop Ukwu. He battles the chevalier's ordinary forces as well as a troop of Old World mamelukes for control of the city and the mouth of the great Mississippi River. Dodging between these rival titans, a crew of Catalan pirates--whose captain was once a close associate of Mad Hannah Penn--grapples with the chevalier over the fate of one of their mates. Meanwhile, a failed ceremony and a sick infant send the Anishinaabe hunter Ma'iingan on a journey across the Empire to Cavalier Johnsland, to a troubled foster child named Nathaniel. Ma'iingan is promised that Nathaniel is a mighty healer and can save his imperiled baby, but first Nathaniel--a pale young man with a twisted ear who hears the voices of unseen beings--must himself be rescued, from oppression, imprisonment, and madness. Praise for Witchy Eye and D.J. Butler: \"

Findings in animal models demonstrate that activity within hierarchically early sensory cortical regions can be modulated by cross-sensory inputs through resetting of the phase of ongoing intrinsic neural oscillations. Here, subdural recordings evaluated whether phase resetting by auditory inputs would impact multisensory integration processes in human visual cortex. Results clearly showed auditory-driven phase reset in visual cortices and, in some cases, frank auditory event-related potentials (ERP) were also observed over these regions. Further, when audiovisual bisensory stimuli were presented, this led to robust multisensory integration effects which were observed in both the ERP and in measures of phase concentration. These results extend findings from animal models to human visual cortices, and highlight the impact of cross-sensory phase resetting by a non-primary stimulus on multisensory integration in ostensibly unisensory cortices. •Auditory driven phase reset occurs over visual cortices.•This can lead to an auditory evoked potential.•Multisensory interactions occur extensively in visual cortices.•In visual regions, auditory phase resetting interacts with evoked visual activity.

Provides information on accommodations, restaurants, shopping, entertainment, and outdoor activities, along with suggested itineraries and an overview of the history and culture of the region.