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Water pollution
\"Pollution is harmful waste that enters the air, soil, and water. About 40 percent of rivers in the United States are too polluted for fishing, swimming, and other water sports. Learn more in [this book]\"--Back cover.
Book
Energy Democracy
A global energy war is underway.It is man versus nature, fossil fuel versus clean energy, the haves versus the have-nots, and, fundamentally, an extractive economy versus a regenerative economy.
eBook
Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection
Arenaviruses such as Lassa virus (LASV) can cause severe hemorrhagic fever in humans. As a major impediment to vaccine development, delayed and weak neutralizing antibody (nAb) responses represent a unifying characteristic of both natural infection and all vaccine candidates tested to date. To investigate the mechanisms underlying arenavirus nAb evasion we engineered several arenavirus envelope-chimeric viruses and glycan-deficient variants thereof. We performed neutralization tests with sera from experimentally infected mice and from LASV-convalescent human patients. NAb response kinetics in mice correlated inversely with the N-linked glycan density in the arenavirus envelope protein’s globular head. Additionally and most intriguingly, infection with fully glycosylated viruses elicited antibodies, which neutralized predominantly their glycan-deficient variants, both in mice and humans. Binding studies with monoclonal antibodies indicated that envelope glycans reduced nAb on-rate, occupancy and thereby counteracted virus neutralization. In infected mice, the envelope glycan shield promoted protracted viral infection by preventing its timely elimination by the ensuing antibody response. Thus, arenavirus envelope glycosylation impairs the protective efficacy rather than the induction of nAbs, and thereby prevents efficient antibody-mediated virus control. This immune evasion mechanism imposes limitations on antibody-based vaccination and convalescent serum therapy.
Journal Article
أبي معي
قصة رقيقة برسومات دافئة، نرى فيها بطلتها الصغيرة وهي تتحدث عن والدها، وتصف لنا كيف تكون الأشياء والأمور حين يكون معها، وكيف يصنع وجوده، الفارق الأهم في حياتها. إنه الأب، ذلك الحامي، الطيب، والمحب، الذي يستطيع أن يجعل كل شيء ممكنا. في هذه القصة صنعت لنا الرسامة سوش أبا عملاقا وضخما وأكبر بكثير من حجم طفلته الصغيرة، لأنها هكذا ترى الأب، ولأنها الطريقة التي يرى بها الكثير منا آباءنا وأبطالنا. إنه الشخص الموجود من أجل أن يحبك من دون أسباب وبلا شروط وإلى الأبد. إنه الشخصية التي نأمل في قرارة أنفسنا أن نكونها من أجل أطفالنا، والتي نأمل أن يكونوها هم من أجل أطفالهم يوما ما. أبي معي، قصة تنقل لنا السحر الكامن بين ابنة وأب، وهو بالنسبة لها أكبر من هذه الحياة.
BOOK
Integral green Zimbabwe
Integral Green Zimbabwe: An African Phoenix Rising by Ronnie Lessem, Alexander Schieffer and Liz Mamukwa is the first book in the Integral Green Society and Economy series, a series which has three overarching aims. The first aim is to link together two major movements of our time, one philosophical, the other practical. The philosophical movement is towards what many today are calling an 'integral' age, while the practical is the 'green' movement, duly aligned with that of sustainable development. The second is to blend together elements of nature and community, culture and spirituality, science and technology, politics and economics, thus serving to bring about an 'integral green' vision, albeit with a focus on business and economics. As such, the authors transcend the limitations to sustainable development and environmental economics, which are overly ecological, if not also technological, in orientation, and exclude social and cultural elements. Thirdly, this particular volume focuses specifically on Zimbabwe, as well as Southern Africa, drawing on the particular issues and capacities that this country and region represents. The emphasis on Zimbabwe and Southern Africa transpired not only because two of the editors (Lessem and Mamukwa) are Zimbabwean in origin, but because Zimbabwe is today like a phoenix rising from the ashes, and has the opportunity to recreate itself anew.
eBook
Progressive Corporate Law
315Reflecting recent reexaminations of the nature and purpose of the modern publicly held corporation, Progressive Corporate Law introduces the reader to alternative perspectives within the field. The contributors to this volume are loosely bound both by their rejection of the prevailing paradigm of the corporation as a public good designed exclusively for the maximization of private profit and by their affirmative goal of designing corporate laws that accord better with the corporation's political and social realities. The resulting series of visions emphasizes communitarian themes of efficiency and morality of responsibility, altruism, and unity within the corporate form as well as between the corporation and the broader society.
Progressive Corporate Law is important reading for business executives, lawyers, policymakers, and others who are concerned with the role of corporations in modem life. Designed to act as a springboard for stimulating discussion, it will be a valuable supplement to courses and seminars in corporate law and business ethics.
eBook
