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The increased frequency of extreme weather events due to climate change has complicated the epidemiological pattern of mosquito-borne diseases, as the host and vector dynamics shift to adapt. However, little is known about the seroprevalence of common mosquito-borne virus infections in horses in Australia. In this study, serological surveys for multiple alphaviruses were performed on samples taken from 622 horses across two horse populations (racehorses and horses residing on The University of Queensland (UQ) campus) in Queensland using the gold standard virus neutralization test. As is the case in humans across Australia, Ross River virus (RRV) is the most common arbovirus infection in horses, followed by Barmah Forest virus, with an overall apparent seroprevalence of 48.6% (302/622) and 4.3% (26/607), respectively. Horses aged over 6 years old (OR 1.86, p = 0.01) and residing at UQ (OR 5.8, p < 0.001) were significantly associated with seroconversion to RRV. A significant medium correlation (r = 0.626, p < 0.001) between RRV and Getah virus (GETV) neutralizing antibody titers was identified. Collectively, these results advance the current epidemiological knowledge of arbovirus exposure in a susceptible host in Australia. The potential use of horses as sentinels for arbovirus monitoring should be considered. Furthermore, since GETV is currently exotic to Australia, antibodies cross-reactivity between RRV and GETV should be further investigated for cross-protection, which may also help to inform vaccine developments.

To determine feasibility and estimate the effect of a 10-week tai chi chuan (TCC) intervention on anxiety and sleep quality in young adults. Seventy-five adults (18-40 years) from a predominately undergraduate midsized university. This was an assessor blinded, randomized feasibility trial, and participants were randomized into one of three groups: 10 weeks of TCC meeting 2 times per week, 10 weeks of TCC with a DVD of the curriculum, and control group receiving a handout on anxiety management. Anxiety and sleep quality were assessed 4 times: baseline, 4 weeks, 10 weeks (immediate post-intervention), and 2 months post-intervention. Retention was defined as a participant attending the baseline assessment and at least one other assessment. Adherence to the intervention was set a priori as attendance at 80% of the TCC classes. Eighty-five percent of participants were retained during the intervention and 70% completed the 2 month follow-up assessments. To increase statistical power, the two TCC groups were combined in the analyses of anxiety and sleep quality measures. No significant changes in anxiety were found in the control group, while levels of anxiety decreased significantly over time in the two TCC groups. Sleep quality scores improved across time for all three groups, but adherent TCC participants reported greater improvement than control participants. TCC may be an effective nonpharmaceutical means of improving anxiety and poor sleep quality in young adults.

[...]I would say the work we do at our bimonthly hearings is the tip of the iceberg. Tommie then earned her JD from the University of Pennsylvania, where she was a member of the law review. [...]Tommie was a founding mother of the Washington Area Women's Foundation, a community-supported foundation thatinvests in the power of women and girls of color in the Washington, D.C., region.

PurposeBecause preservice teachers (PSTs) need effective strategies to address the risks of teaching hard history, teacher educators must select approaches and strategies for teaching PSTs how to avoid, contain, or embrace the risks of teaching hard history. The purpose of this study was to explore one teacher educator’s strategies for teaching PSTs how to contain the risks of teaching hard history.Design/methodology/approachThis study reports partial findings from Phase I of a multiple case research study of PSTs during their secondary social studies methods class and student teaching experiences during the 2021–2022 academic year. Data included surveys, semi-structured interviews, non-participant observations, and documents.FindingsFindings indicate that the teacher educator taught five strategies for containing risk while simultaneously enacting risk containment herself. Four of the risk containment strategies shared characteristics with prior research; one strategy, grounding teaching in the state social studies standards, is a novel strategy that adds to the existing body of research.Originality/valueThis study contributes to and extends the research on containing the risk of teaching hard history in secondary social studies. One strategy taught by the teacher educator, grounding teaching in the state social studies standards, adds to the body of scholarship on teacher educators’ strategies for containing the risks of teaching hard history.

According to the Administrative Office of the U.S. Courts and the U.S. Judicial Panel on Multidistrict Litigation, MDLs constituted 38 percent of the federal civil docket in 2019. [...]the Panel must determine \"that transfers for such proceedings will be for the convenience of parties and witnesses,\" and, third, that they \"will promote the just and efficient conduct of such actions.\" Alternatives such as informal coordination among the parties and involved courts, as well as transfer under Section 1404 for coordinated or consolidated pretrial proceedings, allow the actions to proceed through pretrial in the court that eventually will try the case. Since the JPMLs inception, it has created more than 1,800 MDL litigation dockets and has denied more than 790 motions for centralization. Every two months, the JPML holds a hearing at a different courthouse to consider these motions. Because we are a national court, we make an effort to hold hearings in all regions of the country each year.

After publication of the original article [1], the authors notified that that one of the BNTRC institutional collaborator names was misspelled.After publication of the original article [1], the authors notified that that one of the BNTRC institutional collaborator names was misspelled.

In a trial that compared a 2-week course of dexamethasone with placebo in patients with a chronic subdural hematoma, a favorable outcome on the modified Rankin scale at 6 months was more common in the placebo group than in the dexamethasone group, but repeat surgery to evacuate a hematoma was performed more frequently in the placebo group.

Objective: This study examined whether mindfulness increased through participation in movement-based courses and whether changes in self-regulatory self-efficacy, mood, and perceived stress mediated the relationship between increased mindfulness and better sleep. Participants: 166 college students enrolled in the 2007-2008 academic year in 15 week classes in Pilates, Taiji quan, or GYROKINESIS. Methods: At beginning, middle, and end of the semester, participants completed measures of mindfulness, self-regulatory self-efficacy, mood, perceived stress, and sleep quality. Results: Total mindfulness scores and mindfulness subscales increased overall. Greater changes in mindfulness were directly related to better sleep quality at the end of the semester after adjusting for sleep disturbance at the beginning. Tiredness, Negative Arousal, Relaxation, and Perceived Stress mediated the effect of increased mindfulness on improved sleep. Conclusions: Movement-based courses can increase mindfulness. Increased mindfulness accounts for changes in mood and perceived stress, which explain, in part, improved sleep quality.

We evaluated the safety and efficacy of closed-loop basal insulin delivery during sleep and after regular meals and unannounced periods of exercise. Twelve adolescents with type 1 diabetes (five males; mean age 15.0 [SD 1.4] years; HbA1c 7.9 [0.7]%; BMI 21.4 [2.6] kg/m(2)) were studied at a clinical research facility on two occasions and received, in random order, either closed-loop basal insulin delivery or conventional pump therapy for 36 h. During closed-loop insulin delivery, pump basal rates were adjusted every 15 min according to a model predictive control algorithm informed by subcutaneous sensor glucose levels. During control visits, subjects' standard infusion rates were applied. Prandial insulin boluses were given before main meals (50-80 g carbohydrates) but not before snacks (15-30 g carbohydrates). Subjects undertook moderate-intensity exercise, not announced to the algorithm, on a stationary bicycle at a 140 bpm heart rate in the morning (40 min) and afternoon (20 min). Primary outcome was time when plasma glucose was in the target range (71-180 mg/dL). Closed-loop basal insulin delivery increased percentage time when glucose was in the target range (median 84% [interquartile range 78-88%] vs. 49% [26-79%], P = 0.02) and reduced mean plasma glucose levels (128 [19] vs. 165 [55] mg/dL, P = 0.02). Plasma glucose levels were in the target range 100% of the time on 17 of 24 nights during closed-loop insulin delivery. Hypoglycemia occurred on 10 occasions during control visits and 9 occasions during closed-loop delivery (5 episodes were exercise related, and 4 occurred within 2.5 h of prandial bolus). Day-and-night closed-loop basal insulin delivery can improve glucose control in adolescents. However, unannounced moderate-intensity exercise and excessive prandial boluses pose challenges to hypoglycemia-free closed-loop basal insulin delivery.