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The genomic characteristics of Peruvian patients with gastric adenocarcinoma from diverse socioeconomic backgrounds were examined in consideration of the possibility that patients from different socioeconomic backgrounds may be exposed to different risk factors. We conducted a prospective pilot study in two Peruvian cities (Lima and Ica). This study enrolled 15 patients from low socioeconomic status (LSES) and 15 patients from medium/high socioeconomic status (MHSES). The genomic profiling of gastric adenocarcinoma samples was done through the FoundationOne CDx platform. We compared the genomic characteristics and the need for targeted therapy and immunotherapy between LSES and MHSES. The genes with higher rates of alterations were TP53 (73.3% vs. 50.0%, P  = 0.2635); CDH1 (26.7% vs. 28.6%, P  = 1); CDKN2A (20.0% vs. 28.6%, P = 1); KRAS (33.3% vs. 7.1%, P  = 0.1686); ARID1A (20.0% vs. 14.3%, P  = 1); MLL2 (13.3% vs. 21.4%, P  = 1) and SOX9 (33.3% vs. 0.0%, P  = 0.0421) in LSES versus HMSES, respectively. There was no significant difference in tumor mutational burden ( P  = 0.377) or microsatellite status ( P  = 1). The LSES group had a higher need for targeted therapy or immunotherapy according to gene involvement and alterations. A significant genomic difference exists among patients with gastric adenocarcinoma of different socioeconomic status, which may result in a different need for targeted therapy and immunotherapy.

The National Electric Energy Agency (ANEEL) of Brazil, in a bid to encourage energy-conscious energy consumption, has proposed a new sustainable energy tariff modality (the White Tariff) based on off-peak usage. This study aims to compare and contrast situations in which the White Tariff alone is used, and where it is combined with power generation from a generator set or a photovoltaic cell energy system to reduce energy costs. Furthermore, economic, environmental, and social advantages are outlined in the project summaries. Interviews and documentary analyses were conducted in a technology park that uses only the White Tariff and in condominiums that combine the White Tariff with a generator set or a photovoltaic cell system. The data generated was fed into the database of the Horosazonal software to obtain an overview of these companies. Results show that the company adopting the White Tariff alone achieved 19% and US $14,684 in annual savings. However, when the White Tariff is combined with a generator set, the smart grid project proved to be more efficient over time as it obtained an annual benefit of US$ 35,832 and 62.38% savings. In contrast, the smart grid project combining a photovoltaic cell energy system with the White Tariff achieved an annual benefit of US$52,712, with 68.31% savings and was 1.3 to 5.3 times more profitable than other projects, demonstrating that it was the best smart grip project studied. Furthermore, opting for the White Tariff produced advantages such as a reduction in energy consumption expenses, contributing to a reduction in power outages and blackouts, reduction in greenhouse gas emissions and boosting the company image within society. This study shows that energy-conscious consumption combined with the use of renewable energy sources is environmentally and economically advantageous and can provide future generations with a healthier environment in which people can make use of natural resources in a sustainable manner that is sustainable for planet earth.

Lead is a persistent heavy metal in the soil that can accumulate in edible plants, so non-polluting strategies are required for its removal. In this study, the efficiency of weeds with associated rhizobacteria in phytoremediation of soil contaminated with lead (800 ppm) was investigated. Weeds with lead tolerance were selected, as well as rhizobacteria that promote plant growth in vitro. Several bacterial consortia (BC) were applied on three weed species, and the weight of the aboveground biomass of the weeds, the phytotoxicity of the soil after phytoremediation, as well as the parameters of the phytoremediation of lead in the soil with lower phytotoxicity, were evaluated. As a result, 20% of the weeds analyzed were tolerant to lead with indices of 0.80 (Echinochloa colona (L.) Link), 0.76 (Cyperus corymbosus Rottb.), and 0.72 (Sorghum halepense). BC solubilized phosphates, produced indole acetic acid, and increased the fresh biomass of plants (4.14-14.32%). Furthermore, the lowest level of phytotoxicity in the soil was detected in the treatment of E. colona (L.) Link with Pseudomonas spp. and Acinetobacter spp. (BC1), as well as a bioaccumulation factor of 0.1650 in the foliage, 1.0250 in the roots, and a translocation factor of 0.1611. Finally, 78.83% lead removal was determined in E. colona (L.) Link with rhizobacteria, compared to the 57.58% obtained with E. colona (L.) Link without rhizobacteria. The efficiency of the association of weeds and plant growth-promoting rhizobacteria in the phytoremediation of soils contaminated with lead was demonstrated.

In the field of sports psychology, the influence of mood states on athletic performance has been a topic of research in recent decades and given the importance of having valid and reliable tools in the Peruvian context, the present study aimed to translate and analyze the validity, reliability, and sex invariance of the BRUMS Mood Scale in Peruvian athletes. The sample consisted of 377 university athletes from different sports disciplines, with ages ranging from 18 to 24 years, and a mean age of 20.60 years (SD = 1.94), with 64.5% being male and 35.5% female. The BRUMS Mood Scale test was used. The findings of this research on the mood scale for university sports have shown that this instrument is reliable and valid for assessing emotional states in this comparable setting for young men and women. The studies on content validity, structure, and reliability corroborate the quality and uniformity of the instrument in the Peruvian context. En el ámbito de la psicología deportiva, la influencia de los estados de ánimo en el desempeño deportivo ha sido tema de investigación en las últimas décadas y ante la importancia de contar con herramientas validas y confiables en el contexto peruano, la presente investigación tuvo como objetivo traducir y analizar la validez, confiabilidad e invarianza de sexo en deportistas peruanos de la escala de Estados de Ánimo BRUMS. La muestra estuvo conformada por 377 deportistas universitarios de diferentes disciplinas deportivas, con edades que oscilan entre los 18 y 24 años, y una edad media de 20.60 años (DE = 1.94), siendo el 64.5% varones y 35.5% mujeres. Se utilizo la prueba Escala de Estados de Ánimo de BRUMS. Los hallazgos de esta investigación acerca de la escala de estados de ánimo para el deporte universitario han evidenciado que este instrumento es fiable y válido para evaluar los estados emocionales en este escenario comparable para hombres y mujeres jóvenes. Los estudios de validez de contenido, estructura y fiabilidad corroboran la calidad y uniformidad del instrumento en el contexto peruano. No âmbito da psicologia esportiva, a influência dos estados de ânimo no desempenho esportivo tem sido tema de pesquisa nas últimas décadas e, diante da importância de contar com ferramentas válidas e confiáveis no contexto peruano, a presente investigação teve como objetivo traduzir e analisar a validade, confiabilidade e invariância de sexo em atletas peruanos da escala de Estados de Ânimo BRUMS. A amostra foi composta por 377 atletas universitários de diferentes disciplinas esportivas, comidades que variam entre 18 e 24 anos, e uma idade média de 20.60 anos (DP = 1.94), sendo 64.5% homens e 35.5% mulheres. Foi utilizada a prova Escala de Estados de Ânimo de BRUMS. Os achados desta pesquisa sobre a escala de estados de ânimo para o esporte universitário evidenciaram que este instrumento é confiável e válido para avaliar os estados emocionais neste cenário comparável para homens e mulheres jovens. Os estudos de validade de conteúdo, estrutura e confiabilidade corroboram a qualidade e uniformidade do instrumento no contexto peruano.

Mining operations have a significant impact on environment, where the quality of water is an important affected issue that need to be controlled. In that way, the Grey Clustering Method based on center-point triangular whitenization weight (CTWF), is an artificial intelligence criterion that evaluates water samples according to selected parameters, in order to realize an effective water quality assessment. In the present study, the analysis is made on the Crisnejas River Basin, by using fifteen monitoring points based on an investigation realized by the National Water Authority (ANA) in 2019, based on the Peruvian law (ECA) about water quality standards. The results reveal that almost all of the monitoring points on the Crisnejas River Basin were classified as “irrigation of vegetables unrestricted”, but only one point was classified as “animal drink”, which is ubicated in an urbanized area. This implies that mining discharges are being well treated by the company, but another deal is the contamination generated in towns. Further, the present study might be helpful to audit processes made by the state or companies, to justify the quality of surface waters using a more accurate methodology.