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"Chatterjee, I."
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أنا الشعب : تأملات حول السيادة الشعبية في عالم اليوم
سيجد القارئ في هذا الكتاب تحليلا لتطور الدولة في الفضاء الغربي، بدءا من تنظيرات غرامشي عن «الدولة» المتكاملة، مرورا بدراسة فوكو للسياسات الحيوية وتحليله لديناميكيات عمل النيوليبرالية، وكيف أدت هذه السياسات إلى إيصال النظام السياسي إلى حالة من الفوضى والاضطراب التي هيأت الأرضية لظهور الشعبوية، عبر خلق شرائح واسعة ساخطة يمكن تحشيدها-من قبل قائد كاريزماتي-ضمن مقولة «الشعب» الذي يحارب النخبة الفاسدة المترهلة كما سيجد في هذا الكتاب تحليلا لجذور مفهوم «السيادة الشعبية» ودراسة لآليات الزعامة الشعبوية، التي تسعى إلى خلق هوية عاطفية متينة الشعب عبر سرد الحكايات بدل الحقائق، وتقديم الصور المشحونة مع عاطفيا، ورسم صورة عن «العدو» الخارجي الذي يهدد «الشعب»
Book
Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory
Non-fibrillar soluble oligomeric forms of amyloid-β peptide (oAβ) and tau proteins are likely to play a major role in Alzheimer’s disease (AD). The prevailing hypothesis on the disease etiopathogenesis is that oAβ initiates tau pathology that slowly spreads throughout the medial temporal cortex and neocortices independently of Aβ, eventually leading to memory loss. Here we show that a brief exposure to extracellular recombinant human tau oligomers (oTau), but not monomers, produces an impairment of long-term potentiation (LTP) and memory, independent of the presence of high oAβ levels. The impairment is immediate as it raises as soon as 20 min after exposure to the oligomers. These effects are reproduced either by oTau extracted from AD human specimens, or naturally produced in mice overexpressing human tau. Finally, we found that oTau could also act in combination with oAβ to produce these effects, as sub-toxic doses of the two peptides combined lead to LTP and memory impairment. These findings provide a novel view of the effects of tau and Aβ on memory loss, offering new therapeutic opportunities in the therapy of AD and other neurodegenerative diseases associated with Aβ and tau pathology.
Journal Article
Damage Prediction of Pre-cracked High-Pressure Pipelines
Due to the increasing need to transport fluids, the use of industrial pipes and their sustainability is a crucial aspect to address. The motive of this work is to predict the behaviour of a pre-cracked pipeline under internal and external pressure using Finite element simulation. An intermediate range of pressure conditions has been selected to analyse the dispersal of normalized stress intensity factor along a semi elliptical crack front for a predefined crack geometry. This work also presents a comparative study of various piping material behaviour to address a relatively better choice for industrial use. Among the various alloys considered in the analysis Inconel 625 was found to be most appropriate for the pressure range.
Journal Article
The history of vitamin C research in India
Vitamin C is perhaps the most controversial, highly publicised yet least understood of all vitamins. Eighty years have passed since its discovery, but till now its precise biological function has remained an enigma. The history of vitamin C research in India is presented.
Journal Article
How are they othered? Globalisation, identity and violence in an Indian city
The literature on conflict claims that there has been a resurgence of ethnic conflict in the era of globalisation. This paper attempts to investigate how local conflict may be influenced by processes of globalisation. The paper argues that in order to understand how globalisation may be implicated in local violent events, it is essential to develop a nuanced understanding of the complexities of global—local interaction in places. This paper also hopes to contribute to the analytical potency of identity-oriented explanations of conflict by explicating how identity construction has an overt spatial dimension — it is simultaneously place based and global, and how this global—local identity construction simultaneously produces socioeconomic and socio-cultural strategies of 'othering' that define the complexion of contemporary conflicts. Using interviews from a case study of Hindu— Muslim conflict which happened in 2002 in Ahmedabad city, India, this paper explicates how locally embedded global narratives socioeconomically and socio-culturally produce the 'other.'
Journal Article
Social conflict and the neoliberal city: a case of Hindu-Muslim violence in India
In an era of globalisation the 'global' is very much implicated in the 'local'. Local events like conflicts therefore need to be understood in the context of the dynamics of globalisation. This paper argues that neoliberal globalisation undergoes a thorough grounding in accordance with the pre-existing socio-cultural and economic specificities of places, which impact upon inter-community alienation and conflict. Using four case studies from a Hindu-Muslim conflict in a neoliberalising city, Ahmedabad, India, this paper illustrates how open market policies are implicated in local industrial restructuring and urban renewal that simultaneously utilise place-specific ethnocentrism to exclude and fragment the poor.
Journal Article
Predictors and Outcome Associated with an Enterococcus Positive Isolate during Intensive Care Unit Admission
This study reports the incidence, risk factors and mortality associated with a positive Enterococcus spp. isolate during admission to two tertiary intensive care units participating in an antibiotic cycling study. Incidence was low, with only 4.2% of admissions (36/852) at Royal Brisbane and Women's Hospital and 2.8% (31/1104) at Westmead Hospital developing a positive Enterococcus spp. isolate (P=0.087). A positive enterococcal isolate, while not an independent predictor of mortality (odds ratio [OR] = 1.6, 95% confidence internal [CI] 0.80 to 3.2, P=0.18), may be a marker of the underlying severity of illness with higher unadjusted in-hospital mortality (26% or 17/66 vs 14% or 250/1855, P=0.007). Independent risk factors for a positive isolate were use of meropenem/imipenem (OR=5.7, 95% CI 2.4 to 14, P <0.001) and cefepime (OR=2.5, 95% CI 1.2 to 5.3, P=0.017) within 48 hours of intensive care unit admission, the presence of a nasogastric tube (OR=4.1, 95% CI 1.3 to 14, P=0.018), renal replacement therapy (OR=2.2, 95% CI 1.0 to 4.7, P=0.046), operative intervention (OR=1.8, 95% CI 1.0 to 3.2, P=0.035) and age (OR=1.2, 95% CI 1.1 to 1.5, P=0.009). None of these factors, except for the need for renal replacement therapy (OR=6.2, 95% CI 1.4 to 27, P=0.015), was associated with increased mortality. Enterococci-directed empiric therapy in the treatment of sepsis remains of unproven value, although this negative finding must be evaluated against other higher powered studies.
Journal Article