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Salvation through Refinement (liandu 鍊度) is a distinctive Daoist rite aimed at rescuing the souls of the deceased from hell, enabling their rebirth, and ultimately facilitating their transcendence. The Golden Writings on the Great Achievement of Deliverance by the Numinous Treasure of Highest Clarity (Shangqing Lingbao Jidu Dacheng Jinshu 上清靈寶濟度大成金書), compiled by Zhou Side 周思得 (1359–1451), preserves a wealth of material related to Salvation through Refinement. This content can be divided into two parts: the ritual procedures of Salvation through Refinement and the associated internal practices (neishi 内事). Zhou explicitly stated that the Salvation through Refinement ritual originated from the Golden Book of Salvation according to the Lingbao Tradition (Lingbao Lingjiao Jidu Jinshu 靈寶領教濟度金書), compiled by Lin Lingzhen 林靈真 (1239–1302), whereas the internal practices are not attributed to any specific source. Comparative analysis confirms that the section on internal practices derives from the Brief Discussions of Inner Method of Taiji for Sacrificing to and Sublimating [the Souls of the Deceased] (Taiji Jilian Neifa Yilüe 太極祭鍊內法議略), compiled by Zheng Sixiao 鄭思肖 (1241–1318). Zheng Sixiao’s Salvation through Refinement method centers on Visualization and Actualization (cunxiang 存想), with the entire process taking place internally within the ritual master’s body. Building upon this foundation, Zhou Side incorporated additional ritualized actions and recitations, striving to integrate external ritual with internal practice. In doing so, he constructed a model of Salvation through Refinement characterized by the union of inner methods and outer rites. Inner Sublimation emerged during the Southern Song period, likely influenced in both principle and method by the then-prevalent School of the Mind (xinxue 心學). It sought to counter the increasing complexity of ritual practices at that time. Meanwhile, the continued practice of traditional forms of Retreats (zhai 齋) and Offerings (jiao 醮) reflected the Ming (1368–1644) rulers’ emphasis on the didactic function of such rituals. In his compilation, Zhou cited the views and materials of others under the name of Tian Sizhen 田思真 (fl. early 12th century) to articulate the inner meanings and core doctrines of the Numinous Treasure (lingbao 靈寶) rites. By positioning Tian Sizhen as an intermediary, Zhou not only established a line of transmission between the rites he compiled and the orthodox Numinous Treasure lineage represented by Lu Xiujing 陸修靜 (406–477) but also affirmed his conscious identification with the Daoist ritual tradition and his stance regarding its lineage.

We demonstrate that the thermoelectric properties of p-type chalcogenides can be effectively improved by band convergence and hierarchical structure based on a high-entropy-stabilized matrix. The band convergence is due to the decreased light and heavy band energy offsets by alloying Cd for an enhanced Seebeck coefficient and electric transport property. Moreover, the hierarchical structure manipulated by entropy engineering introduces all-scale scattering sources for heat-carrying phonons resulting in a very low lattice thermal conductivity. Consequently, a peak zT of 2.0 at 900 K for p-type chalcogenides and a high experimental conversion efficiency of 12% at Δ T  = 506 K for the fabricated segmented modules are achieved. This work provides an entropy strategy to form all-scale hierarchical structures employing high-entropy-stabilized matrix. This work will promote real applications of low-cost thermoelectric materials. The synergism of entropy engineering and the typical optimization mechanisms in high-entropy-stabilized chalcogenide is unknown. Here, the authors find high-entropy-stabilized composition works as a promising matrix of applying synergistic effect to realize high thermoelectric performance.

Fruits are the defining feature of angiosperms, likely have contributed to angiosperm successes by protecting and dispersing seeds, and provide foods to humans and other animals, with many morphological types and important ecological and agricultural implications. Rosaceae is a family with ∼3000 species and an extraordinary spectrum of distinct fruits, including fleshy peach, apple, and strawberry prized by their consumers, as well as dry achenetum and follicetum with features facilitating seed dispersal, excellent for studying fruit evolution. To address Rosaceae fruit evolution and other questions, we generated 125 new transcriptomic and genomic datasets and identified hundreds of nuclear genes to reconstruct a well-resolved Rosaceae phylogeny with highly supported monophyly of all subfamilies and tribes. Molecular clock analysis revealed an estimated age of ∼101.6 Ma for crown Rosaceae and divergence times of tribes and genera, providing a geological and climate context for fruit evolution. Phylogenomic analysis yielded strong evidence for numerous whole genome duplications (WGDs), supporting the hypothesis that the apple tribe had a WGD and revealing another one shared by fleshy fruit-bearing members of this tribe, with moderate support for WGDs in the peach tribe and other groups. Ancestral character reconstruction for fruit types supports independent origins of fleshy fruits from dry-fruit ancestors, including the evolution of drupes (e.g., peach) and pomes (e.g., apple) from follicetum, and drupetum (raspberry and blackberry) from achenetum. We propose that WGDs and environmental factors, including animals, contributed to the evolution of the many fruits in Rosaceae, which provide a foundation for understanding fruit evolution.

Flexible thermoelectric devices show great promise as sustainable power units for the exponentially increasing self-powered wearable electronics and ultra-widely distributed wireless sensor networks. While exciting proof-of-concept demonstrations have been reported, their large-scale implementation is impeded by unsatisfactory device performance and costly device fabrication techniques. Here, we develop Ag 2 Se-based thermoelectric films and flexible devices via inkjet printing. Large-area patterned arrays with microscale resolution are obtained in a dimensionally controlled manner by manipulating ink formulations and tuning printing parameters. Printed Ag 2 Se-based films exhibit (00  l )-textured feature, and an exceptional power factor (1097 μWm −1 K −2 at 377 K) is obtained by engineering the film composition and microstructure. Benefiting from high-resolution device integration, fully inkjet-printed Ag 2 Se-based flexible devices achieve a record-high normalized power (2 µWK −2 cm −2 ) and superior flexibility. Diverse application scenarios are offered by inkjet-printed devices, such as continuous power generation by harvesting thermal energy from the environment or human bodies. Our strategy demonstrates the potential to revolutionize the design and manufacture of multi-scale and complex flexible thermoelectric devices while reducing costs, enabling them to be integrated into emerging electronic systems as sustainable power sources. Ag 2 Se-based flexible thermoelectric devices are fabricated by inkjet printing technology, which demonstrate exceptional power generation performance owing to unique patterning capability and high-resolution device integration.

Three-dimensional (3D) printing is emerging as a transformative technology for biomedical engineering. The 3D printed product can be patient-specific by allowing customizability and direct control of the architecture. The trial-and-error approach currently used for developing the composition of printable inks is time- and resource-consuming due to the increasing number of variables requiring expert knowledge. Artificial intelligence has the potential to reshape the ink development process by forming a predictive model for printability from experimental data. In this paper, we constructed machine learning (ML) algorithms including decision tree, random forest (RF), and deep learning (DL) to predict the printability of biomaterials. A total of 210 formulations including 16 different bioactive and smart materials and 4 solvents were 3D printed, and their printability was assessed. All ML methods were able to learn and predict the printability of a variety of inks based on their biomaterial formulations. In particular, the RF algorithm has achieved the highest accuracy (88.1%), precision (90.6%), and F1 score (87.0%), indicating the best overall performance out of the 3 algorithms, while DL has the highest recall (87.3%). Furthermore, the ML algorithms have predicted the printability window of biomaterials to guide the ink development. The printability map generated with DL has finer granularity than other algorithms. ML has proven to be an effective and novel strategy for developing biomaterial formulations with desired 3D printability for biomedical engineering applications.

• Rice (Oryza sativa) is a short-day (SD) plant originally having strong photoperiod sensitivity (PS), with SDs promoting and long days (LDs) suppressing flowering. Although the evolution of PS in rice has been extensively studied, there are few studies that combine the genetic effects and underlying mechanism of different PS gene combinations with variations in PS. • We created a set of isogenic lines among the core PS-flowering genes Hd1, Ghd7 and DTH8 using CRISPR mutagenesis, to systematically dissect their genetic relationships under different day-lengths. We investigated their monogenic, digenic, and trigenic effects on target gene regulation and PS variation. • We found that Hd1 and Ghd7 have the primary functions for promoting and repressing flowering, respectively, regardless of day-length. However, under LD conditions, Hd1 promotes Ghd7 expression and is recruited by Ghd7 and/or DTH8 to form repressive complexes that collaboratively suppress the Ehd1-Hd3a/RFT1 pathway to block heading, but under SD conditions Hd1 competes with the complexes to promote Hd3a/RFT1 expression, playing a tradeoff relationship with PS flowering. Natural allelic variations of Hd1, Ghd7 and DTH8 in rice populations have resulted in various PS performances. • Our findings reveal that rice PS flowering is controlled by crosstalk of two modules – Hd1–Hd3a/RFT1 in SD conditions and (Hd1/Ghd7/DTH8)–Ehd1–Hd3a/RFT1 in LD conditions – and the divergences of these genes provide the basis for rice adaptation to broad regions.

Many superionic mixed ionic–electronic conductors with a liquid-like sublattice have been identified as high efficiency thermoelectric materials, but their applications are limited due to the possibility of decomposition when subjected to high electronic currents and large temperature gradients. Here, through systematically investigating electromigration in copper sulfide/selenide thermoelectric materials, we reveal the mechanism for atom migration and deposition based on a critical chemical potential difference. Then, a strategy for stable use is proposed: constructing a series of electronically conducting, but ion-blocking barriers to reset the chemical potential of such conductors to keep it below the threshold for decomposition, even if it is used with high electric currents and/or large temperature differences. This strategy not only opens the possibility of using such conductors in thermoelectric applications, but may also provide approaches to engineer perovskite photovoltaic materials and the experimental methods may be applicable to understanding dendrite growth in lithium ion batteries. Mixed ionic–electronic conductors are limited by material decomposition. Here the authors reveal the mechanism for atom migration and deposition in Cu 2– δ (S,Se) materials based on a critical chemical potential difference and propose electronically conducting, ion-blocking interfaces to enhance stability.

Reperfusion injury is still a major challenge that impedes neuronal survival in ischemic stroke. However, the current clinical treatments are remained on single pathological process, which are due to lack of comprehensive neuroprotective effects. Herein, a macrophage‐disguised honeycomb manganese dioxide (MnO2) nanosphere loaded with fingolimod (FTY) is developed to salvage the ischemic penumbra. In particular, the biomimetic nanoparticles can accumulate actively in the damaged brain via macrophage‐membrane protein‐mediated recognition with cell adhesion molecules that are overexpressed on the damaged vascular endothelium. MnO2 nanosphere can consume excess hydrogen peroxide (H2O2) and convert it into desiderated oxygen (O2), and can be decomposed in acidic lysosome for cargo release, so as to reduce oxidative stress and promote the transition of M1 microglia to M2 type, eventually reversing the proinflammatory microenvironment and reinforcing the survival of damaged neuron. This biomimetic nanomedicine raises new strategy for multitargeted combined treatment of ischemic stroke. Macrophage‐disguised FTY‐loaded MnO2 nanoparticles (Ma@(MnO2+FTY)) are engineered to salvage the ischemic penumbra. Nanoparticles can accumulate actively in the ischemic region to protect neurons directly via consuming ROS and generating O2. In addition, the nanoparticles can also reverse the proinflammatory microenvironment by promoting the phenotypic transition of microglia through multiple signaling pathways, increasing the protection effects on damaged neurons.

The operating temperature of a submarine cable must be lower than its permissible limit to prevent degradation of the insulation material. Ground conditions influence the heat transfer between the cable and the surrounding soil, thereby affecting both the cable temperature and its economic efficiency. This paper investigates the effect of ground conditions on the thermal performance and economic efficiency of a three-core 220 kV AC XLPE submarine cable. A coupled finite element model based on electromagnetic, thermal, and pore water flow fields is developed and the effects of laying depth, initial temperature, soil thermal conductivity, and permeability on the thermal performance and economic efficiency of the cable are investigated via parametric studies. The results show that the conductor temperature increases with increasing laying depth, and this effect becomes more pronounced at greater laying depths. The conductor temperature increases linearly with increasing initial temperature and decreases nonlinearly with increasing soil thermal conductivity. When the soil permeability is greater than 10 −11  m 2 , the conductor temperature decreases as the soil permeability increases. From a thermal-economic perspective, the economic efficiency of submarine cables can be improved by laying cables in soil with high thermal conductivity or decreasing the laying depth. Laying cables in soil with higher permeability to improve cost-effectiveness is effective only when the soil permeability exceeds 10⁻ 11 m 2 .