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result(s) for
"Cherix, Christophe"
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Yoko Ono : one woman show 1960-1971
Catalog of an exhibition held at the Museum of Modern Art, New York, May 17-Sept. 7, 2015.
Breaking Down Categories
2013
Throughout the world, most public collections of prints and drawings represent only one of the components of the traditional fine-arts museum. The nature of the pieces in such collections—at times midway between document and work of art—requires their curators to consider them outside the strict boundaries of a particular medium and to remain in close contact with the museum’s other departments. An engraving can be an original work of art, with no counterparts in other mediums, or it can be a work of reproduction (the printmaker copies a painting by another artist, for instance). In fact, some prints
Book Chapter
Adrian Piper : a synthesis of intuitions, 1965-2016
Adrian Piper has consistently produced groundbreaking work that has profoundly shaped the form and content of conceptual art since the 1960s. Strongly inflected by her longstanding involvement with philosophy and yoga, her pioneering investigations into the political, social, psychological and spiritual potential of conceptual art have had an incalculable influence on artists working today. Published in conjunction with the most comprehensive exhibition of her work to date, this catalog presents more than 280 artworks that encompass the full range of Piper's mediums.
The Moment of Marcel Broodthaers? A Conversation
2016
On the occasion of Marcel Broodthaers's first retrospective in New York at the Museum of Modern Art and forty years after his death in 1976,
presents a roundtable discussion on the Belgian artist's career and legacy. Exhibition curators Christophe Cherix and Manuel Borja-Villel join Benjamin H. D. Buchloh, Rachel Haidu, Rosalind Krauss, and Trevor Stark for a conversation on Broodthaers's work, his artistic development, and his reception. Topics include the indeterminacy between language and visuality; the status of film in his work; his meditations on the commodity, the art market, and the historical role of cultural institutions; his ambivalent relationship with Pop, Minimalism, and Conceptual Art; and national identity and decolonization.
Journal Article
4th Annual New Prints Review
2007
Presents a survey of works by 30 contemporary artists, chosen by 'Art on Paper' magazine for their innovative work in paper-based editions. Profiles Geoff McFetridge, a Los Angeles-based Canadian graphic designer, whose gallery installations include his trade-mark wallpaper designs, and discusses 'Pumpkin Poster' (2006; col. illus.) by American artist Charles Ray, the text-based prints inspired by Samuel Pepys' diaries by Los Angeles-based Monique Prieto, the politically engaged and provocative posters of New York duo Kayrock and Wolfy (Karl J. LaRocca and Jef Scharf), the series 'Artist's Stock Certificate' (2007; col. illus.) produced by New York-based Japanese artist Yukinori Yanagi as part of his investigation of the workings of money and power, and the 'sculptural prints' of Colombian artist Miler Lagos which look like tree stumps, but which are in fact piles of thousands of prints taken from Albrecht Dürer's 'Apocalypse' wood engravings.
Magazine Article
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
by
Neftel, Cyril
,
Mullen, John T.
,
Sud, Malika
in
631/208/514/1949
,
631/250/1619/554
,
631/67/327
2021
Synovial sarcoma (SyS) is an aggressive neoplasm driven by the SS18–SSX fusion, and is characterized by low T cell infiltration. Here, we studied the cancer–immune interplay in SyS using an integrative approach that combines single-cell RNA sequencing (scRNA-seq), spatial profiling and genetic and pharmacological perturbations. scRNA-seq of 16,872 cells from 12 human SyS tumors uncovered a malignant subpopulation that marks immune-deprived niches in situ and is predictive of poor clinical outcomes in two independent cohorts. Functional analyses revealed that this malignant cell state is controlled by the SS18–SSX fusion, is repressed by cytokines secreted by macrophages and T cells, and can be synergistically targeted with a combination of HDAC and CDK4/CDK6 inhibitors. This drug combination enhanced malignant-cell immunogenicity in SyS models, leading to induced T cell reactivity and T cell–mediated killing. Our study provides a blueprint for investigating heterogeneity in fusion-driven malignancies and demonstrates an interplay between immune evasion and oncogenic processes that can be co-targeted in SyS and potentially in other malignancies.
Single-cell transcriptional profiling of primary human synovial sarcoma tumors suggests that combinatorial treatment with HDAC and CDK4/CDK6 inhibitors could enhance tumor immunogenicity.
Journal Article
Codeine accumulation and elimination in larvae, pupae, and imago of the blowfly Lucilia sericata and effects on its development
2008
The aim of this study was to evaluate the reliability of insect larvae as samples for toxicological investigations. For this purpose, larvae of
Lucilia sericata
were reared on samples of minced pig liver treated with different concentrations of codeine: therapeutic, toxic, and potentially lethal doses. Codeine was detected in all tested larvae, confirming the reliability of these specimens for qualitative toxicology analysis. Furthermore, concentrations measured in larvae were correlated with levels in liver tissue. These observations bring new elements regarding the potential use of opiates concentrations in larvae for estimation of drug levels in human tissues. Morphine and norcodeine, two codeine metabolites, have been also detected at different concentrations depending on the concentration of codeine in pig liver and depending on the substance itself. The effects of codeine on the development of
L. sericata
were also investigated. Results showed that a 29-h interval bias on the evaluation of the larval stage duration calculated from the larvae weight has to be considered if codeine was present in the larvae substrate. Similarly, a 21-h interval bias on the total duration of development, from egg to imago, has to be considered if codeine was present in the larvae substrate.
Journal Article
Codeine accumulation and elimination in larvae, pupae, and imago of the blowfly @@iLucilia sericata@ and effects on its development
2008
The aim of this study was to evaluate the reliability of insect larvae as samples for toxicological investigations. For this purpose, larvae of @@iLucilia sericata@ were reared on samples of minced pig liver treated with different concentrations of codeine: therapeutic, toxic, and potentially lethal doses. Codeine was detected in all tested larvae, confirming the reliability of these specimens for qualitative toxicology analysis. Furthermore, concentrations measured in larvae were correlated with levels in liver tissue. These observations bring new elements regarding the potential use of opiates concentrations in larvae for estimation of drug levels in human tissues. Morphine and norcodeine, two codeine metabolites, have been also detected at different concentrations depending on the concentration of codeine in pig liver and depending on the substance itself. The effects of codeine on the development of @@iL. sericata@ were also investigated. Results showed that a 29-h interval bias on the evaluation of the larval stage duration calculated from the larvae weight has to be considered if codeine was present in the larvae substrate. Similarly, a 21-h interval bias on the total duration of development, from egg to imago, has to be considered if codeine was present in the larvae substrate.
Journal Article