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21
result(s) for
"Chiang, Chih-Yun"
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Outcome and cost analysis of primary total knee arthroplasty in end-stage renal disease patients: A nationwide population-based study
by
Fan Chiang, Chih-Yun
,
Chang, Chee-Jen
,
Hsieh, Pang-Hsin
in
Arthroplasty (knee)
,
Arthroplasty, Replacement, Hip
,
Arthroplasty, Replacement, Knee - adverse effects
2021
A number of patients with end-stage renal disease (ESRD) undergo total knee arthroplasty (TKA) due to advanced knee joint osteoarthritis. There are few studies describing the incidence, morbidities, mortality rate, and cost analysis regarding ESRD patients receiving TKA.
We retrospectively retrieved patient data from National Health Insurance Research Database in Taiwan during 2005-2011, and evaluated the outcomes of TKA in patients with (ESRD group) and without ESRD (non-ESRD group). Patients' demographic data, comorbidities, mortality, and in-hospital cost were recorded.
A total of 578 TKAs and 110,895 TKAs were identified in the ESRD and non-ESRD group, respectively. The incidence of patients receiving TKA was higher in the ESRD than in non-ESRD group by at least 2 folds. The ESRD group showed significantly more medical complications (pneumonia, peptic ulcer disease, and acute myocardial infarction) after surgery. In prosthesis-related complications, the ESRD group also had more periprosthetic joint infections, and prosthetic loosenings by one year. The one-year mortality rate was more than 6 times higher in the ESRD than in the non-ESRD group. The ESRD group had higher in-hospital medical expense than the non-ESRD group, especially when there were complications, even when the dialysis-related costs were exempted.
The complication rate, mortality rate, and cost were higher in the ESRD patients receiving TKA. When considering TKA in ESRD patients, it is crucial to weigh the risks against benefits of TKA, and have a thorough discussion with the patients.
Journal Article
Study on the Coexistence of Offshore Wind Farms and Cage Culture
by
Fang, Hui-Ming
,
Chiang, Yun-Chih
,
Wang, Hsing-Yu
in
Clean technology
,
Environmental aspects
,
Fish industry
2021
In this study, a hydrodynamic model was used that includes the effects of wave–current interactions to simulate the wave and current patterns before and after offshore wind turbine installation in western Taiwan. By simulating the waves and currents after the offshore wind turbine was established, the waves and currents caused by the wind turbine were seen to have a limited range of influence, which is probably within an area about four to five times the size of the diameter (12–15 m) of the foundation structure. Overall, the analysis of the simulation results of the wave and current patterns after the offshore wind turbines were established shows that the underwater foundation only affected the local area near the pile structure. The wind farm (code E) of the research case can be equipped with about 720 cage cultures; if this is extended to other wind farms in the western sea area, it should be possible to produce economic-scale farming operations such as offshore wind power and fisheries. However, this study did not consider the future operation of the entire offshore wind farm. If the operation and maintenance of offshore wind farms are not affected, and if the consent of the developer is obtained, it should be possible to use this method to provide economically large-scale farming areas as a mutually beneficial method for offshore wind power generation and fisheries.
Journal Article
Designing Rainwater Harvesting Systems Cost-Effectively in a Urban Water-Energy Saving Scheme by Using a GIS-Simulation Based Design System
2015
Current centralized urban water supply depends largely on energy consumption, creating critical water-energy challenge especially for many rapid growing Asian cities. In this context, harvesting rooftop rainwater for non-potable use has enormous potential to ease the worsening water-energy issue. For this, we propose a geographic information system (GIS)-simulation-based design system (GSBDS) to explore how rainwater harvesting systems (RWHSs) can be systematically and cost-effectively designed as an innovative water-energy conservation scheme on a city scale. This GSBDS integrated a rainfall data base, water balance model, spatial technologies, energy-saving investigation, and economic feasibility analysis based on a case study of eight communities in the Taipei metropolitan area, Taiwan. Addressing both the temporal and spatial variations in rainfall, the GSBDS enhanced the broad application of RWHS evaluations. The results indicate that the scheme is feasible based on the optimal design when both water and energy-savings are evaluated. RWHSs were observed to be cost-effective and facilitated 21.6% domestic water-use savings, and 138.6 (kWh/year-family) energy-savings. Furthermore, the cost of per unit-energy-saving is lower than that from solar PV systems in 85% of the RWHS settings. Hence, RWHSs not only enable water-savings, but are also an alternative renewable energy-saving approach that can address the water-energy dilemma caused by rapid urbanization.
Journal Article
A Study on the Influence of Suspended Matter by the Foundation Construction of Different Offshore Wind Turbines in the Taiwan Sea Area
by
Chiang, Yun-Chih
,
Hsiao, Sung-Shan
,
Wang, Hsing-Yu
in
Air-turbines
,
Boundary conditions
,
Clean technology
2021
The objective of this study was to adequately examine potential wave fields, flow fields, and suspended load changes in different wind turbine foundations. Accordingly, this study applied the hydrodynamic model to simulate waves, currents, and suspended load in the study area. The simulation results are based on the assumption that dredging and rubble bed trimming were performed for 8 h and that the per foundation setting operation was completed in 2 h. The influence on the tripile and jacket was larger than that on the monopile, and the influence time was longer. However, due to the influence of tidal currents on the sea, the suspended load also became more acceptable than the initial concentration. From a macroscopic perspective, the different foundations did not sufficiently affect the study area. From a microscopic perspective, changes in the suspended load were only limited to areas surrounding the piles after the installation of the wind turbines.
Journal Article
Integrating Early Transcriptomic Responses to Rhizotoxins in Rice ( Oryza sativa. L.) Reveals Key Regulators and a Potential Early Biomarker of Cadmium Toxicity
2017
As sessile organisms, plants were constantly challenged with biotic and abiotic stresses. Transcriptional activation of stress-responsive genes is a crucial part of the plant adaptation to environmental changes. Here, early response of rice root to eight rhizotoxic stressors: arsenate, copper, cadmium, mercury, chromate, vanadate, ferulic acid and juglone, was analyzed using published microarray data. There were 539 general stress response (GSR) genes up-regulated under all eight treatments, including genes related to carbohydrate metabolism, phytohormone balance, and cell wall structure. Genes related to transcriptional coactivation showed higher
ratio compared to the other GSR genes. Network analysis discovered complicated interaction within GSR genes and the most connected signaling hubs were
, and
. Promoter analysis discovers enriched SCGCGCS
-element in GSR genes. Moreover, GSR genes tend to be intronless and genes with shorter total intron length were induced in a higher level. Among genes uniquely up-regulated by a single stress, a phosphoenolpyruvate carboxylase kinase (PPCK) was identified as a candidate biomarker for detecting cadmium contamination. Our findings provide insights into the transcriptome dynamics of molecular response of rice to different rhizotoxic stress and also demonstrate potential use of comparative transcriptome analysis in identifying a novel potential early biomarker.
Journal Article
Yanliao Beach Nourishment Methods
by
Fang, Hui-Ming
,
Chiang, Yun-Chih
,
Wang, Hsing-Yu
in
Beach erosion
,
Beach nourishment
,
Beaches
2018
Yanliao Beach, part of Taiwan's Northeast Coast National Scenic Area, is a major sightseeing and recreation spot. In recent years, the number of tourists has increased, and maintaining the beach's recreation function has become crucial. In 2007, Typhoon Krosa caused substantial beach erosion at Yanliao Beach; sand dunes collapsed, resulting in a beach scarp and endangering facilities toward the back of the beach. To protect the sand dunes and beach scarp of the post-typhoon topography, based on long-term Yanliao Beach topographic survey information and long-term tidal water level records, this study conducted an integrated artificial beach nourishment method that comprised replenishing the coastal beach and dunes. The planned areas for sand replenishment were those above the mean high water line. This beach nourishment measure protected the dunes from collapsing further and mitigated the risk of beach nourishment polluting the water in front of the beach. Topographic survey results revealed that the large amount of sand deposited in the intertidal zone resulted in the 0 m shoreline advancing toward the seaside. The width of the beach increased, indicating the success of this integrated beach nourishment method.
Journal Article
From Gamer to Game Designer: Task-Oriented Game Design Learning to Improve Learning Motivation
by
Hong, Shuo-Jun
,
Lin, Heng-Sheng
,
Wu, Chao-Cian
in
Academic Achievement
,
Active Learning
,
Alphabets
2025
Taiwanese students learn Chinese from 3 years old using Bopomofo (Zhuyin Fuhao), but they still struggle with spelling and reading, even in middle school. Thus, we guided students still struggling to read Chinese text to use their logical skills and creativity to incorporate the Bopomofo phonetic alphabet into the Rummikub strategy board game. Over six weeks of tutoring, the students shifted from a passive to an active learning attitude, enhancing their enthusiasm for learning. The Zhuyin Fuhao Rummikub board game developed by them received positive feedback in several areas: game experience (4.42/5), self-assessment of learning outcomes (4.31/5), clarity of rules (4.52/5), and learning motivation (3.85/5 and 3.79/5). These results indicate that the board game is highly effective and well-received, underscoring its value in Chinese language learning and teaching. In conclusion, this teaching module can benefit students, educators, and parents. Educators can use this game-based design to inspire the creation of more engaging instructional content.
Journal Article
Development of Simple Sequence Repeats (SSR) Markers in Setaria italica (Poaceae) and Cross-Amplification in Related Species
by
Lin, Heng-Sheng
,
Kuoh, Chang-Sheng
,
Chiang, Chih-Yun
in
Alleles
,
DNA, Plant - genetics
,
Genetic diversity
2011
Foxtail millet is one of the world’s oldest cultivated crops. It has been adopted as a model organism for providing a deeper understanding of plant biology. In this study, 45 simple sequence repeats (SSR) markers of Setaria italica were developed. These markers showing polymorphism were screened in 223 samples from 12 foxtail millet populations around Taiwan. The most common dinucleotide and trinucleotide repeat motifs are AC/TG (84.21%) and CAT (46.15%). The average number of alleles (Na), the average heterozygosities observed (Ho) and expected (He) are 3.73, 0.714, 0.587, respectively. In addition, 24 SSR markers had shown transferability to six related Poaceae species. These new markers provide tools for examining genetic relatedness among foxtail millet populations and other related species. It is suitable for germplasm management and protection in Poaceae.
Journal Article
Theorizing ambivalence in Ang Lee's transnational cinema: The discourse of Chinese identity between the local and the global
2010
Using ambivalence as a theoretical framework, this study examines Ang Lee’s cinematic discourse of Chinese identity, which is co-constructed with the audiences from different cultural communities. I focus on Ang Lee’s transnational films Crouching Tiger Hidden Dragon and Lust, Caution as my two case studies. By analyzing the audience discourse from Taiwan, Mainland China, and overseas Chinese communities, I am able to conceptualize their reactions as communicative moments that co-construct the meaning of the film text. I suggest that ambivalence is a self-representational strategy for the ethnic “Other,” who is historically denied access to representation, to contest and subvert the conventional stereotyping and simplification of one’s subjectivity. Additionally, this research provides a good example of the familiar cycle of ambivalent emotion toward the West, in the aftermath of postcolonialism. China and Taiwan’s long history of engaging in a subordinate relationship with the West enhances the resurgence of ambivalence. Representations become a significant and predominant way to mediate one’s bodily experiences, to connect and collaborate with one another, and to form and inform one’s cultural identity. My research furthers the theorization of the ways in which new media technologies impact and alter the human interactions between peoples from various cultural, social, and political contexts.
Dissertation
Long-Term Yo-Yo Dieting Exaggerates Liver Steatosis and Lesions but Preserves Muscle Performance in Male Zebrafish
by
Hsu, Tzu-Chieh
,
Chen, Ching-Yi
,
Liu, I-Hsuan
in
Adipose Tissue - metabolism
,
Adipose tissues
,
Animals
2024
Weight regain within one year after weight loss is frequently observed and is referred to as yo-yo dieting or weight cycling. In this study, we explore the effects of yo-yo dieting on the liver, adipose tissue, and muscle characteristics of male zebrafish. Four-month-old AB wild-type male zebrafish were randomly assigned to three groups: high-calorie intake (H, seven meals per day), low-calorie intake (L, two meals per day), and yo-yo diet (the low- and high-calorie alternation switched every two weeks) groups. Feeding the fish the H diet for over 8 weeks led to steatosis and damage to the liver. The yo-yo diet reduced liver lipid accumulation at week eight but caused a similar degree of lipid accumulation as the H diet thereafter. It was found that twenty weeks of yo-yo dieting actually exacerbated hepatic damage. Compared to the L diet, feeding the fish on the yo-yo and H diets for a period of 20 weeks significantly increased the size of muscle fibers, resulting in higher speed during burst swimming and a significant increase in the size and number of adipocytes in the abdominal tissue. To summarize, short-term yo-yo dieting was found to attenuate hepatosteatosis and maintain fast-twitch muscle function. Long-term yo-yo dieting preserved fast-twitch muscle function and muscle fiber size; however, it exacerbated the pathological changes in the liver.
Journal Article