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Azimuthal asymmetries in semi-inclusive production of positive ( h + ) and negative hadrons ( h − ) have been measured by scattering 160 GeV muons off longitudinally polarised deuterons at CERN. The asymmetries were decomposed in several terms according to their expected modulation in the azimuthal angle φ of the outgoing hadron. Each term receives contributions from one or several spin and transverse-momentum-dependent parton distribution and fragmentation functions. The amplitudes of all φ -modulation terms of the hadron asymmetries integrated over the kinematic variables are found to be consistent with zero within statistical errors, while the constant terms are nonzero and equal for h + and h − within the statistical errors. The dependencies of the φ -modulated terms versus the Bjorken momentum fraction x , the hadron fractional momentum z , and the hadron transverse momentum were studied. The x dependence of the constant terms for both positive and negative hadrons is in agreement with the longitudinal double-spin hadron asymmetries, measured in semi-inclusive deep-inelastic scattering. The x dependence of the sin  φ -modulation term is less pronounced than that in the corresponding HERMES data. All other dependencies of the φ -modulation amplitudes are consistent with zero within the statistical errors.

Large samples of Λ , Σ (1385) and Ξ (1321) hyperons produced in the deep-inelastic muon scattering off a 6 LiD target were collected with the COMPASS experimental setup at CERN. The relative yields of Σ (1385) + , Σ (1385) − , , , Ξ (1321) − , and hyperons decaying into were measured. The ratios of heavy-hyperon to Λ and heavy-antihyperon to were found to be in the range 3.8 % to 5.6 % with a relative uncertainty of about 10 %. They were used to tune the parameters relevant for strange particle production of the LEPTO Monte Carlo generator.

The aim of the present study was to investigate the therapeutic efficacy of genetically engineered stem cells (GESTECs) expressing bacterial cytosine deaminase (CD) and/ or human interferon-beta (IFN-β) gene against HeLa cervical cancer and the migration factors of the GESTECs toward the cancer cells. Anticancer effect of GESTECs was examined in a co-culture with HeLa cells using MTT assay to measure cell viability. A transwell migration assay was performed so as to assess the migration capability of the stem cells to cervical cancer cells. Next, several chemoattractant ligands and their receptors related to a selective migration of the stem cells toward HeLa cells were determined by real-time PCR. The cell viability of HeLa cells was decreased in response to 5-fluorocytosine (5-FC), a prodrug, indicating that 5-fluorouracil (5-FU), a toxic metabolite, was converted from 5-FC by CD gene and it caused the cell death in a co-culture system. When IFN-β was additionally expressed with CD gene by these GESTECs, the anticancer activity was significantly increased. In the migration assay, the GESTECs selectively migrated to HeLa cervical cancer cells. As results of real-time PCR, chemoattractant ligands such as MCP-1, SCF, and VEGF were expressed in HeLa cells, and several receptors such as uPAR, VEGFR2, and c-kit were produced by the GESTECs. These GESTECs transduced with CD gene and IFN- β may provide a potential of a novel gene therapy for anticervical cancer treatments via their selective tumor tropism derived from VEGF and VEGFR2 expressions between HeLa cells and the GESTECs.

Abstract The production of beauty hadrons was measured via semi-leptonic decays at mid-rapidity with the ALICE detector at the LHC in the transverse momentum interval 1