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We conducted a helicopter survey in 2010 for cliff-nesting raptors along the Dalton Highway in northern Alaska. The study area extended from the Yukon River northward ~395 km through the Brooks Range to the Arctic Plain. We documented 55 occupied raptor nesting territories, including 25 Golden Eagle (Aquila chrysaetos), 11 Gyrfalcon (Falco rusticolus), and 10 Peregrine Falcon (Falco peregrinus) territories. We also recorded vacant stick nests and raptor perch sites on cliffs. We identified more occupied eagle territories and hundreds more vacant eagle stick nests than were previously known in the study area. The average number of Golden Eagle nestlings/nesting pairs at the time of the survey was 1.5 ± 0.6. The most productive Golden Eagle pairs were located in the northern part of the study area. The number of occupied eagle territories in 2010 is far fewer than the number of eagle stick nests we recorded. Our data indicate that the distribution of nesting eagles in the 2010 study area is different than in the past. Whether this reflects changes in eagle density; a response to availability of prey, climate change, human activities, or a combination of these; or some other factor warrants further investigation. Intensive surveys along the Dalton Highway in the 1970s found no occupied nests for Peregrine Falcons or Gyrfalcons but we found 10 and 11, respectively. Therefore, the Peregrine Falcon and Gyrfalcon nests we recorded in 2010 reflect an increase in the number of known nesting pairs there.

Understanding the genetics of a population is a critical component of developing conservation strategies. We used archived tissue samples from golden eagles (Aquila chrysaetos canadensis) in three geographic regions of western North America to conduct a preliminary study of the genetics of the North American subspecies, and to provide data for United States Fish and Wildlife Service (USFWS) decision-making for golden eagle management. We used a combination of mitochondrial DNA (mtDNA) D-loop sequences and 16 nuclear DNA (nDNA) microsatellite loci to investigate the extent of gene flow among our sampling areas in Idaho, California and Alaska and to determine if we could distinguish birds from the different geographic regions based on their genetic profiles. Our results indicate high genetic diversity, low genetic structure and high connectivity. Nuclear DNA Fst values between Idaho and California were low but significantly different from zero (0.026). Bayesian clustering methods indicated a single population, and we were unable to distinguish summer breeding residents from different regions. Results of the mtDNA AMOVA showed that most of the haplotype variation (97%) was within the geographic populations while 3% variation was partitioned among them. One haplotype was common to all three areas. One region-specific haplotype was detected in California and one in Idaho, but additional sampling is required to determine if these haplotypes are unique to those geographic areas or a sampling artifact. We discuss potential sources of the high gene flow for this species including natal and breeding dispersal, floaters, and changes in migratory behavior as a result of environmental factors such as climate change and habitat alteration. Our preliminary findings can help inform the USFWS in development of golden eagle management strategies and provide a basis for additional research into the complex dynamics of the North American subspecies.

ObjectiveThe Canadian Real-world Evidence for Value in Cancer (CanREValue) Collaboration was established in response to growing interest in using real-world evidence (RWE) to support health technology assessment (HTA). CanREValue has developed a framework to generate and use RWE to inform cancer drug funding decisions.Design and participantsThe RWE framework was developed using a multistage, multistakeholder approach. First, an environmental scan and qualitative study were conducted to understand the current state and key stakeholder perspectives on RWE. Next, five formal working groups (WGs) were established consisting of stakeholders with cancer drug funding expertise including clinicians, patients, methodologists, payers, regulatory decision-makers and data analysts. Through stakeholder consultations, including modified Delphi exercises and workshops, each WG developed specific framework components and identified facilitators and barriers that may impact the uptake of RWE.SettingThe CanREValue Collaboration consisted of membership and participation from stakeholders and expertise from across Canada. Central research operations were managed from Toronto, Ontario, Canada.OutcomesDevelopment of an RWE framework reflective of the needs and perspectives of stakeholders directly involved and/or impacted by cancer drug funding decisions across Canada.ResultsThrough an iterative process, a comprehensive RWE framework was developed that outlined the end-to-end processes necessary for the generation and use of RWE for HTA reassessment in Canada. The framework consists of four phases that uses various tools, templates and processes, which can be applied as a whole or in part. A diverse range of stakeholders and expertise is involved in the decision-making of each phase of the process: Phase I: identification, selection and prioritisation of RWE questions; phase II: initiating and planning the RWE study; phase III: conducting the RWE study and phase IV: conducting reassessment.ConclusionsAs the cancer drug funding landscape continues to evolve, the need for RWE to support evidence-based policy reform, pricing and reallocation of funding from low to high value settings is crucial. We have developed a framework that is adaptable and responsive to the changing landscape. The tools, templates and processes within the framework can be applied by various stakeholder groups in whole or in part to support cancer drug funding decision-making in Canada and can be adapted for use in other jurisdictions.

Diurnal cliff-nesting raptors were inventoried on the Ungalik River, Alaska, in 1977 and 1979. In 2008 we resurveyed the drainage, replicating the techniques used in 1979. The density of nesting raptors during the late nesting season has doubled in the past three decades, from six occupied territories detected in 1977 and four in 1979 to 12 in 2008. A single Peregrine Falcon (Falco peregrinus) was sighted during aerial surveys in 1977, and a pair of Peregrine Falcons was detected during a boat survey in 1979; however, nesting by these birds was not confirmed. In contrast, we detected five occupied Peregrine Falcon territories along the Ungalik River in 2008. Other changes in cliff-nesting raptor occurrence included a decrease in occupied Gyrfalcon (Falco rusticolus) territories from four in 1977 to one in 1979 and two in 2008, a decrease in Rough-legged Hawk (Buteo lagopus) nests from one in 1979 (none in 1977) to none in 2008, and increases in Golden Eagle (Aquila chrysaetos) nests, from two in 1977 and 1979 to five in 2008. Changes in the number of nests of cliff-nesting raptors in this small population may have resulted, in part, from natural variation associated with changes in weather or prey abundance. However, it is likely that the increase in nesting Peregrine Falcons is related to global population recovery. Our data indicate that factors other than available nesting sites limit cliff-nesting raptor numbers along the Ungalik River. Spatial analysis indicated that cliff-nesting raptor nests were most often on hills or cliffs that face away from the coast, which is the source of most storms. En 1977 et en 1979, des rapaces diurnes nichant en falaise ont été répertoriés sur la rivière Ungalik, en Alaska. En 2008, nous avons réalisé de nouveaux relevés dans le bassin hydrographique, en reprenant les techniques employées en 1979. La densité des nids de rapaces en fin de saison de nidification a doublé au cours des trois dernières décennies. En 1977, il y avait six territoires occupés, puis quatre en 1979, et 12 en 2008. Un seul faucon pèlerin (Falco peregrinus) a été vu durant les relevés aériens de 1977 et une paire de faucons pèlerins a été observée pendant un relevé en bateau en 1979, bien que la nidification de ces oiseaux n'ait pas été confirmée. En revanche, en 2008, nous avons observé cinq territoires de faucon pèlerin occupés le long de la rivière Ungalik. Parmi les autres changements dans l'occurrence des rapaces nichant en falaise, on compte une diminution des territoires de faucon gerfaut (Falco rusticolus) occupés, passant de quatre en 1977 à un en 1979, puis à deux, en 2008; une diminution des nids de buse pattue (Buteo lagopus), passant de un en 1979 (aucun en 1977) à aucun en 2008; une augmentation des nids d'aigle royal (Aquila chrysaetos), passant de deux en 1977 et en 1979 à cinq en 2008. Les changements caractérisant le nombre de nids de rapaces nichant en falaise dans cette petite population pourraient découler, en partie, de la variation naturelle liée aux changements climatiques ou de l'abondance des proies. Toutefois, il est probable que l'augmentation de faucons pèlerins en nidification soit liée au rétablissement de la population mondiale. Nos données indiquent que des facteurs autres que les sites de nidification disponibles limitent le nombre de rapaces diurnes nichant en falaise le long de la rivière Ungalik. Une analyse spatiale démontre que les rapaces diurnes nichant en falaise faisaient plus souvent leur nid sur les collines ou les falaises à l'opposé du littoral, d'où proviennent la plupart des tempêtes.

Understanding the genetics of a population is a critical component of developing conservation strategies. We used archived tissue samples from golden eagles (Aquila chrysaetos canadensis) in three geographic regions of western North America to conduct a preliminary study of the genetics of the North American subspecies, and to provide data for United States Fish and Wildlife Service (USFWS) decision-making for golden eagle management. We used a combination of mitochondrial DNA (mtDNA) D-loop sequences and 16 nuclear DNA (nDNA) microsatellite loci to investigate the extent of gene flow among our sampling areas in Idaho, California and Alaska and to determine if we could distinguish birds from the different geographic regions based on their genetic profiles. Our results indicate high genetic diversity, low genetic structure and high connectivity. Nuclear DNA Fst values between Idaho and California were low but significantly different from zero (0.026). Bayesian clustering methods indicated a single population, and we were unable to distinguish summer breeding residents from different regions. Results of the mtDNA AMOVA showed that most of the haplotype variation (97%) was within the geographic populations while 3% variation was partitioned among them. One haplotype was common to all three areas. One region-specific haplotype was detected in California and one in Idaho, but additional sampling is required to determine if these haplotypes are unique to those geographic areas or a sampling artifact. We discuss potential sources of the high gene flow for this species including natal and breeding dispersal, floaters, and changes in migratory behavior as a result of environmental factors such as climate change and habitat alteration. Our preliminary findings can help inform the USFWS in development of golden eagle management strategies and provide a basis for additional research into the complex dynamics of the North American subspecies.

The purpose of this study was to explore the intersectional possibilities between the fields of drama therapy and mental health counseling through the lens of transformative learning theory. Specifically, the research sought to understand the lived experiences of professionals trained in both disciplines to identify how these fields might mutually inform, strengthen, and enhance one another through collaboration and/or dual training. Data were collected through a qualitative online survey and analyzed using thematic analysis. Five themes emerged: (a) Theoretical and Practical Overlaps and Distinctions; (b) Drama Therapy-Informed Counseling: Embodiment, Creativity, and Experiential Practice; (c) Counseling-Informed Drama Therapy: Frameworks for Practice, Education, and Supervision; (d) Navigating Systems and Professional Identity: Challenges and Advantages; and (e) Collaboration for Social Justice: From Theory to Embodiment. These findings highlight integrative opportunities and systemic considerations for interdisciplinary practice in support of socially just, creative, and embodied approaches to mental health care.

Die-offs of sage grouse (Centrocercus urophasianus) were verified in southeastern Idaho in 1981. We captured 82 apparently healthy grouse to quantify the effects of organophosphorus insecticides (OP's) and other pesticides on sage grouse in sagebrush (Artemisia spp.) bordering agricultural lands in July 1985 and 1986. Grouse were fitted with radio collars and tracked through part of each summer. At least 18% of 82 radio-tagged grouse in 1985-86 subsequently occupied fields at the time they were sprayed with OP insecticides dimethoate or methamidophos. Cholinesterase (ChE) assays of brains and residue analysis of crop contents indicated that 5 and 16% of the marked sample died from OP's in 1985 and 1986, respectively. Approximately 200 sage grouse were present in a block of alfalfa sprayed with dimethoate; 63 of these were later found dead and ChE activity in 43 brains suitable for assay were depressed >50%. Maximum residues in crop contents of dead grouse were 18 μg/g methamidophos and 30 μg/g dimethoate. Intoxicated or dead grouse were observed in or near 6 fields sprayed with dimethoate or methamidophos in 1985-86. Twenty of 31 intoxicated grouse radiotagged after being found in dimethoate-sprayed (1986) alfalfa died. Our study indicates that certain pesticides have the potential for adversely affecting grouse populations.