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Extended-spectrum β-lactamase (ESBL)-producing E. coli has become an important global problem for the public health sector. This study aims to investigate the E. coli antimicrobial resistance profile among living food-producing animals in Tamaulipas, Mexico. A total of 200 fecal samples were collected from bovines, pigs, chickens and sheep. A total of 5.0% of the strains were phenotypically confirmed as ESBL producers. A high percentage of phenotypic antimicrobial resistance was observed against gentamicin (93.3%), tetracycline (86.6%) and streptomycin (83.3%). The gentamicin-resistant strains showed MDR, distributed among 27 resistance patterns to different antimicrobials. The antimicrobial resistance gene tet(A) was detected in 73.3% of isolates, aadA1 in 60.0% and sul2 in 43.3% of strains. The blaCTX-M gene was found in 23.3% of strains. The virulence gene hlyA was detected in 43.3% of isolates; stx1 and stx2 were not detected in any strain. The phylotyping indicated that the isolates belonged to groups A (33.3%), B1 (16.6%), B2 (40.0%) and D (10.0%). These results show that food-producing animals might be a reservoir of ESBL-producing bacteria and may play a role in their spread.

El tenis es un deporte que depende del rendimiento neuromuscular para tener un mejor desempeño, independientemente del nivel de práctica. El objetivo de este estudio fue describir la asociación entre variables antropométricas y rendimiento neuromuscular niños tenistas (n=36) pre-púberes, en un rango de edad de (10.15-12.77) años, además de compararlos según el nivel de práctica. Los participantes fueron divididos en dos grupos, el primero fue denominado “competitivos”, con ranking nacional (n=18) edad (11.66 ± .72) y el segundo denominado “recreativos” sin ranking nacional (n=18) edad (11.52 ± .82). Se realizó una antropometría básica incluyendo estatura, peso y masa grasa, además se ejecutaron pruebas de CMJ, lanzamientos de balón medicinal de 2kg con tres técnicas diferentes (derecha, revés y por encima de la cabeza), y velocidades de 10m y 20m. En la comparación de grupos se encontraron diferencias (p≤0.01) en la masa grasa, CMJ y la prueba de 20m, y (p≤0.05) en los lanzamientos de balón medicinal y 10m. La estatura y el CMJ se asociaron a las otras variables evaluadas y los jugadores de nivel competitivo tuvieron mejores atributos antropométricos y neuromusculares que sus contemporáneos de nivel recreativo, tal vez por adaptaciones en edades pre-púberas al tiempo dedicado a la práctica, y a la exigencia competitiva. Palabras clave: Tenis, deporte infanto-juvenil, potencia, velocidad. Abstract. Tennis is a sport that depends on neuromuscular performance during the game, regardless of the level of practice. This study aimed to describe the association between anthropometric and neuromuscular performance in pre-pubertal children tennis players (n=36) aged (10.15-12.77) years and compare them according to the level of practice. The participants were divided into two groups; the first was called \"competitive,\" with a national ranking (n=18) aged (11.66 ± .72), and the second called \"recreational\" non-ranked in the national system (n=18) aged (11.52 ± .82). Basic anthropometry, including height, weight, and fat mass, was performed, as well as CMJ tests, 2kg medicine ball throws with three different techniques (forehand, backhand, and overhead), and 10m and 20m distance speeds. The comparison by groups t- student test found differences of (p≤0.01) in fat mass, CMJ, and the 20m test, and (p≤0.05) in the medicine ball throw and 10m. The height and CMJ variables were strongly associated with the other variables evaluated and competitive-level players had fitter anthropometric and neuromuscular attributes than their recreational-level contemporaries, perhaps due to adaptations in pre-pubertal ages to the time dedicated to the practice and the competitive demand. Keywords: Tennis, youth sports, power, speed.

Neonates have distinctive anatomic and physiologic features that predispose them to obstructive sleep apnea (OSA). The overall prevalence of neonatal OSA is unknown, although an increase in prevalence has been reported in neonates with craniofacial malformations, neurological disorders, and airway malformations. If remained unrecognized and untreated, neonatal OSA can lead to impaired growth and development, cardiovascular morbidity, and can even be life threatening. Polysomnography and direct visualization of the airway are essential diagnostic modalities in neonatal OSA. Treatment of neonatal OSA is based on the severity of OSA and associated co-morbidities. This may include medical and surgical interventions individualized for the affected neonate. Based on this, it is expected that infants with OSA have more significant healthcare utilization.

Antimicrobial-resistant bacteria (ARB) in the ESKAPE group include Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. These pathogens continue to pose a global threat to human health. Urban and non-urban rivers affected by anthropogenic activities such as farming can act as reservoirs for ARB. The influx of wastewater from animal farms and irrigation processes can affect the normal microbiota in surrounding waterbodies. New bacteria, such as those in the ESKAPE family, may be introduced into these waterbodies, since most ESKAPE pathogens are domiciled in humans and animals. There is a dearth of information on the persistence of ESKAPE isolates and their associated health hazards in non-nosocomial settings. Therefore, this review aimed to collect data on the global distribution of ESKAPE pathogens in aquatic systems. PubMed and Google Scholar were searched for articles published from 2009 to 2025. A total of 76 studies published in peer-reviewed journals were included. Data were collected from 21 papers for E. faecium/faecalis, 12 for S. aureus, 15 for K. pneumoniae, 11 for A. baumannii, 8 for P. aeruginosa, and 9 for Enterobacter spp. The findings in this review will increase public health awareness on the significance of ESKAPE pathogens in aquatic systems.

Background: Periodontal disease is the infection and inflammation of the gums, bones, and tissues involved in teeth support, and it is one of the most common diseases affecting pet dogs. Essential oils have shown antimicrobial activity against bacteria causing periodontal disease; therefore, they are considered potential therapeutic agents. Objectives: The main objective was to formulate and evaluate the antimicrobial activity of a 0.2% chlorhexidine canine mouthwash with essential oils. Methods: Three microemulsion formulations were obtained by constructing a pseudo-ternary phase diagram using the phase titration method. Different surfactant agents were evaluated, and hydrogenated castor oil was selected as the emulsifier agent. The antimicrobial activity of oregano essential oil (Origanum vulgare), thyme essential oil (Thymus vulgaris), and the three formulations were evaluated against Staphylococcus aureus, Streptococcus mutans, Streptococcus salivarius, and Escherichia coli. Results: Pure thyme and oregano essential oils showed higher antimicrobial activity than a 0,2% chlorhexidine solution. The formulations with essential oils plus chlorhexidine and chlorhexidine alone showed antimicrobial activity. The formulation containing only essential oils did not show antimicrobial activity. Conclusions: A canine mouthwash was formulated with chlorhexidine and thyme and oregano essential oil. Based on the evaluation of antimicrobial activity, two of the proposed formulations could be a therapeutic option to reduce the risk and prevent periodontal disease in canines.

Tennis is a sport that depends on neuromuscular performance during the game, regardless of the level of practice. This study aimed to describe the association between anthropometric and neuromuscular performance in pre-pubertal children tennis players (n=36) aged (10.15-12.77) years and compare them according to the level of practice. The participants were divided into two groups; the first was called \"competitive,\" with a national ranking (n=18) aged (11.66 ± .72), and the second called \"recreational\" non-ranked in the national system (n=18) aged (11.52 ± .82). Basic anthropometry, including height, weight, and fat mass, was performed, as well as CMJ tests, 2kg medicine ball throws with three different techniques (forehand, backhand, and overhead), and 10m and 20m distance speeds. The comparison by groups t- student test found differences of (p≤0.01) in fat mass, CMJ, and the 20m test, and (p≤0.05) in the medicine ball throw and 10m. The height and CMJ variables were strongly associated with the other variables evaluated and competitive-level players had fitter anthropometric and neuromuscular attributes than their recreational-level contemporaries, perhaps due to adaptations in pre-pubertal ages to the time dedicated to the practice and the competitive demand. El tenis es un deporte que depende del rendimiento neuromuscular para tener un mejor desempeño, independientemente del nivel de práctica. El objetivo de este estudio fue describir la asociación entre variables antropométricas y rendimiento neuromuscular niños tenistas (n=36) pre-púberes, en un rango de edad de (10.15-12.77) años, además de compararlos según el nivel de práctica. Los participantes fueron divididos en dos grupos, el primero fue denominado “competitivos”, con ranking nacional (n=18) edad (11.66 ± .72) y el segundo denominado “recreativos” sin ranking nacional (n=18) edad (11.52 ± .82). Se realizó una antropometría básica incluyendo estatura, peso y masa grasa, además se ejecutaron pruebas de CMJ, lanzamientos de balón medicinal de 2kg con tres técnicas diferentes (derecha, revés y por encima de la cabeza), y velocidades de 10m y 20m. En la comparación de grupos se encontraron diferencias (p≤0.01) en la masa grasa, CMJ y la prueba de 20m, y (p≤0.05) en los lanzamientos de balón medicinal y 10m. La estatura y el CMJ se asociaron a las otras variables evaluadas y los jugadores de nivel competitivo tuvieron mejores atributos antropométricos y neuromusculares que sus contemporáneos de nivel recreativo, tal vez por adaptaciones en edades pre-púberas al tiempo dedicado a la práctica, y a la exigencia competitiva.

In recent decades, the appearance of a group of strains resistant to most β-lactam antibiotics, called extended-spectrum β-lactamases (ESBLs), has greatly impacted the public health sector. The present work aimed to identify the prevalence of ESBL-producing Escherichia coli strains in retail meat from northeast Tamaulipas. A total of 228 meat samples were obtained from 76 different stores. A prevalence of E. coli ESBL of 6.5% (15/228) was detected. All (15/15) of the ESBL strains were multiresistant. Altogether, 40% (6/15) of the strains showed the presence of class 1 integrons. The isolates identified with blaCTX-M (20%) also showed co-resistance with the tet (A and B), str (A and B), and sul (2 and 3) genes. A total of 20% of the strains belonged to the B2 and D phylogroups, which are considered pathogenic groups. None of the ESBL-positive strains contained any of the virulence gene factors tested. The presence of ESBL-producing E. coli strains in meat indicates a potential risk to the consumer. Although most of these strains were classified as commensals, they were found to serve as reservoirs of multiresistance to antimicrobials and, therefore, are potential routes of dispersion of this resistance to other bacteria.

En la Educación Superior, la atención al proceso de la inducción del docente novel cobra cada vez mayor importancia, debido a la multiplicidad de factores que intervienen en la llegada de los nuevos formadores de docentes a las Escuelas Normales. Dentro del estudio se realizan aportes teóricos epistemológicos en torno al proceso de inducción y acompañamiento pedagógico, así como aquellos elementos indispensables en Educación superior, tales como las funciones sustantivas y las políticas públicas que rigen su funcionamiento; elementos esenciales para dar sustento al diseño de un programa de acompañamiento pedagógico, vinculando los procesos de docencia, investigación y extensión/difusión en la Escuela Normal de Educación Física “General Ignacio M. Beteta”.

Antimicrobials are routinely used in human and veterinary medicine. With repeated exposure, antimicrobials promote antibiotic resistance, which poses a threat to public health. In this study, we aimed to determine the susceptibility patterns, virulence factors, and phylogroups of E. coli isolates during the killing process in a bovine slaughterhouse. We analyzed 336 samples (from water, surfaces, carcasses, and feces), and 83.3% (280/336) were positive for E. coli. The most common phenotypic resistances that we detected were 50.7% (142/280) for tetracycline, 44.2% (124/280) for cephalothin, 34.6% (97/280) for streptomycin, and 36.7% (103/280) for ampicillin. A total of 82.4% of the isolates had resistance for at least one antimicrobial, and 37.5% presented multiresistance. We detected a total of 69 different phenotypic resistance patterns. We detected six other resistance-related genes, the most prevalent being tetA (22.5%) and strB (15.7%). The prevalence values of the virulence genes were 5.4% in hlyA, 1.4% in stx1, and 0.7% in stx2. The frequencies of the pathogenic strains (B2 and D) were 32.8% (92/280) and 67.1% (188/280) as commensals A and B1, respectively. E. coli isolates with pathogenic potential and multiresistance may represent an important source of dissemination and a risk to consumers.

In patients with immune thrombotic thrombocytopenic purpura (iTTP), autoantibodies against the metalloprotease ADAMTS13 lead to catastrophic microvascular thrombosis. However, the potential benefits of recombinant human ADAMTS13 (rADAMTS13) in patients with iTTP remain unknown. Here, we report the clinical use of rADAMTS13, which resulted in the rapid suppression of disease activity and complete recovery in a critically ill patient whose condition had proved to be refractory to all available treatments. We also show that rADAMTS13 causes immune complex formation, which saturates the autoantibody and may promote its clearance. Our data support the role of rADAMTS13 as a novel adjunctive therapy in patients with iTTP. In a 28-year-old woman with postpartum immune thrombotic thrombocytopenic purpura, plasma exchange was unsuccessful. Near death while receiving vasopressors, she was treated with recombinant ADAMTS13, and the disease abated.