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\"The X-Men are caught up in the epic Secret Empire event! But what does the new landscape of the Marvel Universe mean for mutantkind? How will Jean, Cyclops, Beast, Angel and Iceman survive in a world dominated by Hydra? And what exactly does Magneto have up his sleeve?\"--Publisher description.

Position was confirmed on a single antero-posterior (AP) abdominal radiograph per local practice, with projection of the tip adjacent to L4/L5 vertebrae at the level of the common iliac vein (figure 2). Table 1 Blood results Name Level Reference range Units pH 7.19 7.35–7.45 Carbon dioxide (CO2) 50 35–46 mm Hg Base excess −9 −2 to +3 mmol/L Bicarbonate (HCO3) 19 22–28 mmol/L Lactate 1.3 0.4–2 mmol/L Sodium (Na) 128 135–145 mmol/L On day 18, left leg and flank oedema evolved with difficulty infusing via the PICC line. While PICC lines deliver essential, lifesaving treatment to neonates, they also carry substantial risks.1 2 It is precisely because of these risks that so many national and regional centres have guidelines and frameworks of practice designed for clinicians who use central venous access devices (CVADs).3–7 PICCs inserted into the lower limbs should ideally thread without resistance, follow a smooth course without kinks or wiggles and sit to the right of the spine, above the level of the renal vessels at L2 but below the level of the cardiac silhouette at T9.1 4–6 On retrospective review, the single AP radiograph taken following insertion of the PICC line did not adhere to all of these principles, and the line malposition was not recognised. Central line Care- PICC insertion in the neonate. 2019.

One of comics' wildest writers takes on the symbiotic super hero! Flash Thompson, the Secret Avenger called Agent Venom, faces Daimon Hellstrom and the Monsters of Evil in a battle to save his soul! But when Venom's psychopathic off spring targets the Microverse, Flash and the new Scarlet Spider must put their rivalries aside to handle the madness of Carnage! Venom says farewell to New York and heads to Philadelphia - but Toxin follows soon after. And the pair of lethal symbiotes may unwittingly unleash something even more deadly! Can Flash battle side-by-side with the original Venom, Eddie Brock, to save the City of Brotherly Love? Plus underworld boss Lord Ogre! The killer called Crossbones! And...a symbiotic sidekick?! Cullen Bunn's explosive Venom run is collected in full!

Large fluctuations in blood pressure complicated this treatment, most likely due to a combination of factors involving medication effects, systemic steal phenomenon and compression of both the superior vena cava and brainstem. Table 1 Summary of medical treatment to reduce mass effect of capillary haemangiomas from day 116 of life Drug, route Dose, frequency Duration of treatment (days of life) Propranolol PO 1 mg/kg three times a day 116—ongoing, aged 10 months Methylprednisolone intravenously 30 mg/kg OD 118–121 Interferon alpha 2a S/C 3 million subunits OD 119–156 Prednisolone intravenously 2 mg/kg OD 121–134 Hydrocortisone PO 3 mg/kg OD 135–160 OD, once daily; PO, orally; S/C, subcutaneous. PHACE (Posterior fossa malformations, haemangioma, arterial anomalies, coarctation of the aorta/cardiac defects and eye abnormalities) syndrome (table 2) was confirmed on MRI angiography by the demonstration of variant arterial anatomy with hypoplasia of both the right vertebral artery and right anterior cerebral artery (A1 segment), and tortuosity of the internal carotid arteries. Table 2 Diagnostic criteria of PHACE syndrome3 Organ systems Major criteria Minor criteria Arterial anomalies Anomaly of major cerebral or cervical arteries *† Dysplasia ‡ of the large cerebral arteries Arterial stenosis or occlusion with or without Moyamoya collaterals Absence or moderate to severe hypoplasia of the large cerebral and cervical arteries Aberrant origin or course of the large cerebral or cervical arteries except common arch variants such as bovine arch Persistent carotid–vertebrobasilar anastomosis (proatlantal segmental, hypoglossal, otic and/or trigeminal arteries) Aneurysm of any of the cerebral arteries Structural brain Posterior fossa brain anomalies Dandy-Walker complex Other hypoplasia/dysplasia of the mid and/or hind brain Midline brain anomalies Malformation of cortical development Cardiovascular Aortic arch anomalies Coarctation of the aorta Dysplasia* Aneurysm Aberrant origin of the subclavian artery with or without a vascular ring Ventricular septal defect Right aortic arch/double aortic arch Systemic venous anomalies Ocular Posterior segment abnormalities Persistent hyperplastic primary vitreous Persistent fetal vasculature Retinal vascular anomalies† Morning glory disc anomaly Optic nerve hypoplasia Peripapillary staphyloma Anterior segment abnormalities Microphthalmia Sclerocornea Coloboma Cataracts Ventral/midline Anomaly of the midline chest and abdomen Sternal defect Sternal pit Sternal cleft Supraumbilical raphe Ectopic thyroid hypopituitarism Midline sternal papule/hamartoma Definite PHACE Haemangioma >5 cm in diameter of the head, including scalp plus one major criteria or two minor criteria† Haemangioma of the neck, upper trunk or trunk and proximal upper extremity Plus two major criteria Possible PHACE   Haemangioma > 5 cm in diameter of the head including scalp plus one minor criteria Haemangioma of the neck, upper trunk or trunk and proximal upper extremity Plus one major or two minor No haemangioma Plus two major criteria *Internal carotid artery, middle cerebral artery, anterior cerebral artery, posterior cerebral artery or vertebrobasilar system †Diagnostic criteria present in this patient ‡Includes kinking, looping, tortuosity and/or dolichoectasia PHACE, posterior fossa malformations, hemangioma, arterial anomalies, coarctation of the aorta/cardiac defects and eye abnormalities.

This case report describes a baby who was diagnosed antenatally with a significant left-sided congenital cystic adenomatoid malformation.

Willowdale, Ont. -- The recent court award of $850,000 for Wilf Paiement's on-ice assault of Dennis...

I asked at the Delta international counter if they knew where Presidential's ticket booth was located. The very polite representative said that it was in the North Terminal. We made our way to the north side through much construction and a maze of plastic sheets and finally reached the North Terminal ticket counters. We walked the length of the counter and saw no sign of Presidential Airlines. As members of the General Assembly debate this year's budget, we citizens need to take note of and applaud the efforts of state leaders to make a significant investment in Georgia's future with their support for education. Gov. Zell Miller's proposal provides vital support for preschool, elementary and secondary education and strengthens our higher- education system in ways that will help Georgia to compete successfully for economic development and ensure a quality work force. I own a business in Conyers. Shortly after I moved to my present location in 1994, a nail shop opened up next door to me. Since that time, I have had numerous customer complaints and have personally experienced health problems related to these fumes. I have had sinus infections, bronchitis and walking pneumonia. I never experienced these problems prior to being placed next to the nail shop, where I and my staff are constantly bombarded with these fumes.

There is increasing evidence that anterior pituitary hormones, traditionally thought to have unitary functions in regulating single endocrine targets, act on multiple somatic tissues, such as bone, fat, and liver. There is also emerging evidence for anterior pituitary hormone action on brain receptors in mediating central neural and peripheral somatic functions. Here, we have created the most comprehensive neuroanatomical atlas on the expression of TSHR, LHCGR, and FSHR. We have used RNAscope, a technology that allows the detection of mRNA at single-transcript level, together with protein level validation, to document Tshr expression in 173 and Fshr expression in 353 brain regions, nuclei and subnuclei identified using the Atlas for the Mouse Brain in Stereotaxic Coordinates . We also identified Lhcgr transcripts in 401 brain regions, nuclei and subnuclei. Complementarily, we used ViewRNA, another single-transcript detection technology, to establish the expression of FSHR in human brain samples, where transcripts were co-localized in MALAT1 -positive neurons. In addition, we show high expression for all three receptors in the ventricular region—with yet unknown functions. Intriguingly, Tshr and Fshr expression in the ependymal layer of the third ventricle was similar to that of the thyroid follicular cells and testicular Sertoli cells, respectively. In contrast, Fshr was localized to NeuN-positive neurons in the granular layer of the dentate gyrus in murine and human brain—both are Alzheimer’s disease-vulnerable regions. Our atlas thus provides a vital resource for scientists to explore the link between the stimulation or inactivation of brain glycoprotein hormone receptors on somatic function. New actionable pathways for human disease may be unmasked through further studies.

Marine snow was implicated in the transport of oil to the seafloor during the Deepwater Horizon oil spill, but the exact processes remain controversial. In this study, we investigated the concentrations and distributions of the 16 USEPA priority polycyclic aromatic hydrocarbons (PAHs) in marine snow aggregates collected during a mesocosm experiment. Seawater only, oil in a water accommodated fraction (WAF), and Corexit-enhanced WAF (DCEWAF) were incubated for 16 d. Both WAF and DCEWAF aggregates were enriched in heavy molecular weight PAHs but depleted in naphthalene. DCEWAF aggregates had 2.6 times more total 16 PAHs than the WAF (20.5 vs. 7.8 µg/g). Aggregates in the WAF and DCEWAF incorporated 4.4% and 19.3%, respectively of the total PAHs in the mesocosm tanks. Our results revealed that marine snow sorbed and scavenged heavy molecular weight PAHs in the water column and the application of Corexit enhanced the incorporation of PAHs into the sinking aggregates.