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Empty-Car Routing in Ridesharing Systems
Understanding the Fundamentals of Empty-Car Routing in Ridesharing Systems
How to efficiently route empty-cars in ridesharing systems? In this paper “Empty-car Routing in Ridesharing Systems,” A. Braverman, J.G. Dai, X. Liu, and L. Ying introduce a novel model based on closed queueing networks and propose an optimization framework to optimize empty-car routing for maximizing system-wide utility functions. We propose a fluid-based optimal routing policy by solving the optimization problem in a large market regime. We establish both process-level and steady-state convergence of the closed queueing network to the fluid-limit and prove the optimal network utility obtained from the fluid-based optimization is an upper bound on the utility in the finite car system for any routing policy under which the closed queueing network has a stationary distribution. This upper bound is achieved asymptotically under the fluid-based optimal routing policy.
This paper considers a closed queueing network model of ridesharing systems, such as Didi Chuxing, Lyft, and Uber. We focus on empty-car routing, a mechanism by which we control car flow in the network to optimize system-wide utility functions, for example, the availability of empty cars when a passenger arrives. We establish both process-level and steady-state convergence of the queueing network to a fluid limit in a large market regime where demand for rides and supply of cars tend to infinity and use this limit to study a fluid-based optimization problem. We prove that the optimal network utility obtained from the fluid-based optimization is an upper bound on the utility in the finite car system for any routing policy, both static and dynamic, under which the closed queueing network has a stationary distribution. This upper bound is achieved asymptotically under the fluid-based optimal routing policy. Simulation results with real-world data released by Didi Chuxing demonstrate the benefit of using the fluid-based optimal routing policy compared with various other policies.
Journal Article
Hydroclimatic trends during 1950–2018 over global land
Global hydroclimatic changes from 1950 to 2018 are analyzed using updated data of land precipitation, streamflow, and an improved form of the Palmer Drought Severity Index. The historical changes are then compared with climate model-simulated response to external forcing to determine how much of the recent change is forced response. It is found that precipitation has increased from 1950 to 2018 over mid-high latitude Eurasia, most North America, Southeast South America, and Northwest Australia, while it has decreased over most Africa, eastern Australia, the Mediterranean region, the Middle East, and parts of East Asia, central South America, and the Pacific coasts of Canada. Streamflow records largely confirm these precipitation changes. The wetting trend over Northwest Australia and Southeast South America is most pronounced in austral summer while the drying over Africa and wetting trend over mid-high latitude Eurasia are seen in all seasons. Coupled with the drying caused by rising surface temperatures, these precipitation changes have greatly increased the risk of drought over Africa, southern Europe, East Asia, eastern Australia, Northwest Canada, and southern Brazil. Global land precipitation and continental freshwater discharge show large interannual and inter-decadal variations, with negative anomalies during El Niño and following major volcanic eruptions in 1963, 1982, and 1991; whereas their decadal variations are correlated with the Interdecadal Pacific Oscillation (IPO) with IPO’s warm phase associated with low land precipitation and continental discharge. The IPO and Atlantic multidecadal variability also dominate multidecadal variations in land aridity, accounting for 90 % of the multidecadal variance. CMIP5 multi-model ensemble mean shows decreased precipitation and runoff and increased risk of drought during 1950–2018 over Southwest North America, Central America, northern and central South America (including the Amazon), southern and West Africa, the Mediterranean region, and Southeast Asia; while the northern mid-high latitudes, Southeast South America, and Northwest Australia see increased precipitation and runoff. The consistent spatial patterns between the observed changes and the model-simulated response suggest that many of the observed drying and wetting trends since 1950 may have resulted at least partly from historical external forcing. However, the drying over Southeast Asia and wetting over Northwest Australia are absent in the 21st century projections.
Journal Article
Evaluation and characterization of waterborne biodegradable polyurethane films for the prevention of tendon postoperative adhesion
Tendon adhesion is a serious problem and it affects tendon gliding and joint motion. Although recent studies have yielded promising results in developing anti-adhesion materials, there are still many problems. Polycaprolactone (PCL)-based polyurethane (PU) has good mechanical properties and biocompatibility, and it has a potential in anti-adhesion applications.
In this study, a series of waterborne biodegradable polyurethane (WBPU) films with different ratios of ionic groups were synthesized. In order to select an effective anti-adhesion film, the WBPU films were cast and characterized for physicochemical properties and biocompatibility.
All WBPU films were non-cytotoxic in the cell viability test and had suitable physicochemical and mechanical properties based on the measurement of zeta potential, water contact angle, mechanical properties, water absorption, thickness change, and gelatin test. To evaluate the anti-adhesion effect, severely injured tendons of rabbits were sutured with the modified Kessler core suture technique and WBPU films were then wrapped around the tendon. Implantation in rabbits showed that the WBPU film had better anti-adhesion effect than PCL films and the untreated control, and demonstrated no significant difference in the anti-adhesion performance from the commercial product Seprafilm based on gross evaluation, histological analysis, and biomechanical assessment.
Compared to Seprafilm and PCL applied in the tendon anti-adhesion, WBPU had better mechanical properties, low inflammatory reaction, and a proper degradation interval.
Journal Article
Characteristics and trends in various forms of the Palmer Drought Severity Index during 1900-2008
The Palmer Drought Severity Index (PDSI) has been widely used to study aridity changes in modern and past climates. Efforts to address its major problems have led to new variants of the PDSI, such as the self‐calibrating PDSI (sc_PDSI) and PDSI using improved formulations for potential evapotranspiration (PE), such as the Penman‐Monteith equation (PE_pm) instead of the Thornthwaite equation (PE_th). Here I compare and evaluate four forms of the PDSI, namely, the PDSI with PE_th (PDSI_th) and PE_pm (PDSI_pm) and the sc_PDSI with PE_th (sc_PDSI_th) and PE_pm (sc_PDSI_pm) calculated using available climate data from 1850 to 2008. Our results confirm previous findings that the choice of the PE only has small effects on both the PDSI and sc_PDSI for the 20th century climate, and the self‐calibration reduces the value range slightly and makes the sc_PDSI more comparable spatially than the original PDSI. However, the histograms of the sc_PDSI are still non‐Gaussian at many locations, and all four forms of the PDSI show similar correlations with observed monthly soil moisture (r = 0.4–0.8) in North America and Eurasia, with historical yearly streamflow data (r = 0.4–0.9) over most of the world's largest river basins, and with GRACE (Gravity Recovery and Climate Experiment) satellite‐observed water storage changes (r = 0.4–0.8) over most land areas. All the four forms of the PDSI show widespread drying over Africa, East and South Asia, and other areas from 1950 to 2008, and most of this drying is due to recent warming. The global percentage of dry areas has increased by about 1.74% (of global land area) per decade from 1950 to 2008. The use of the Penman‐Monteith PE and self‐calibrating PDSI only slightly reduces the drying trend seen in the original PDSI. The percentages of dry and wet areas over the global land area and six select regions are anticorrelated (r = −0.5 to −0.7), but their long‐term trends during the 20th century do not cancel each other, with the trend for the dry area often predominating over that for the wet area, resulting in upward trends during the 20th century for the areas under extreme (i.e., dry or wet) conditions for the global land as a whole (∼1.27% per decade) and the United States, western Europe, Australia, Sahel, East Asia, and southern Africa. The recent drying trends are qualitatively consistent with other analyses and model predictions, which suggest more severe drying in the coming decades. Key Points Recent warming has caused widespread drying over land Use of different PE calculations does alter the above conclusion The drying trend may become more severe in coming decades
Journal Article
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice
Parabacteroides distasonis
(
P. distasonis
) plays an important role in human health, including diabetes, colorectal cancer and inflammatory bowel disease. Here, we show that
P. distasonis
is decreased in patients with hepatic fibrosis, and that administration of
P. distasonis
to male mice improves thioacetamide (TAA)- and methionine and choline-deficient (MCD) diet-induced hepatic fibrosis. Administration of
P. distasonis
also leads to increased bile salt hydrolase (BSH) activity, inhibition of intestinal farnesoid X receptor (FXR) signaling and decreased taurochenodeoxycholic acid (TCDCA) levels in liver. TCDCA produces toxicity in mouse primary hepatic cells (HSCs) and induces mitochondrial permeability transition (MPT) and Caspase-11 pyroptosis in mice. The decrease of TCDCA by
P. distasonis
improves activation of HSCs through decreasing MPT-Caspase-11 pyroptosis in hepatocytes. Celastrol, a compound reported to increase
P. distasonis
abundance in mice, promotes the growth of
P. distasonis
with concomitant enhancement of bile acid excretion and improvement of hepatic fibrosis in male mice. These data suggest that supplementation of
P. distasonis
may be a promising means to ameliorate hepatic fibrosis.
Parabacteroides distasonis
(
P. distasonis
), part of the gut microbiome, was reported to play a role in diabetes, colorectal cancer and inflammatory bowel disease. Here the authors report that
P. distasonis
ameliorates liver fibrosis in studies with male mice, potentially via altered bile acid metabolism and hepatocyte pyroptosis.
Journal Article