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"Daly, Alex"
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A Review of Modifiable Risk Factors in Young Women for the Prevention of Breast Cancer
2021
Breast cancer is the most common cancer diagnosis in women aged less than 40 years and the second most common cause of cancer death in this age group. Global rates of young onset breast cancer have risen steadily over the last twenty years. Although young women with breast cancer have a higher frequency of underlying pathogenic mutations in high penetrance breast cancer susceptibility genes (CSG) than older women, the vast majority of young breast cancer patients are not found to have a germline CSG mutation. There is therefore a need to inform young women regarding non-genetic breast cancer risk factors which have the potential to be influenced by changes in individual behaviour. A Pubmed search was performed using the search terms \"young\" or \"early onset\", and \"breast cancer\" and \"modifiable risk\". Titles and abstracts from peer-reviewed publications were screened for relevance. This review presents evidence for potentially modifiable risk factors of breast cancer risk in young women, including lifestyle factors (physical activity, body habitus, alcohol use, smoking, shift work and socioeconomic factors), reproductive and hormonal factors and iatrogenic risks. The extent to which these factors are truly modifiable is discussed and interactions between genetic and non-genetic risk factors are also addressed. Health care professionals have an opportunity to inform young women about breast health and risk when presenting at a \"teachable moment\", including the benefits of physical activity and alcohol habits as risk factor. More focussed discussions regarding individual personal risk and benefit should accompany conversations regarding reproductive health and take into consideration both non-modifiable and iatrogenic BC risk factors.
Journal Article
The impact of race and ethnicity in breast cancer—disparities and implications for precision oncology
2022
Breast cancer is the most commonly diagnosed cancer worldwide and is one of the leading causes of cancer death. The incidence, pathological features, and clinical outcomes in breast cancer differ by geographical distribution and across racial and ethnic populations. Importantly, racial and ethnic diversity in breast cancer clinical trials is lacking, with both Blacks and Hispanics underrepresented. In this forum article, breast cancer researchers from across the globe discuss the factors contributing to racial and ethnic breast cancer disparities and highlight specific implications of precision oncology approaches for equitable provision of breast cancer care to improve outcomes and address disparities.
Journal Article
Lessons learnt from setting up a UK urgent dental care centre during the COVID-19 pandemic
2021
When the COVID-19 pandemic led to the closure of general dental practices throughout the UK on 23 March 2020, Newcastle Dental Hospital became a regional in-hours urgent dental care hub treating ‘hot’ (COVID-19 positive, self-isolating), ‘warm’ (shielding, vulnerable) and ‘cold’ (other) patients. It provided urgent dental care to over 3,000 patients in the first 6 weeks. With no other urgent dental care centres being operational until 15 April, the hospital was the sole care provider (both during normal working hours and out of hours) to a population of over 3 million for more than 3 weeks. Consideration of staffing requirements, logistics, staff wellbeing, personal protective equipment, referral pathways, clinic setup and management of urgent dental conditions during the COVID-19 pandemic are discussed along with the challenges faced.
Journal Article
Daly: We've made our mistakes in response to Kipnis
by
Daly, Alex
in
Graduate students
2015
Last week, Kipnis announced publicly that she had become the target of a Title IX investigation after two graduate students filed separate complaints against her essay in The Chronicle. Another NU graduate student recently filed another Title IX complaint, this time against Stephen Eisenman, an art professor who publicly discussed the school's investigation into Kipnis.
Newsletter
Daly: The lost letters of LGBTQ
by
Daly, Alex
in
Gays & lesbians
2015
Brian McNaught, in his remarkable book, \"On Being Gay,\" writes with pride for \"those lesbians and gay people of color and disability who struggle to stick with the movement.\" Because we often find ourselves forgetting their existence.
Newsletter
The Spectrum: The 'gayest thing' you've ever done
2015
First and foremost, try complaining about that whole \"marriage equality\" issue.
Newsletter
QA with indie darlings Local Natives
2010
With musicalcomparisons to Grizzly Bear, The Fleet Foxes, and Broken SocialScene, this extremely creative group delivers withbeautifully-crafted harmonies, soul-pounding drums, and overall, awonderfully unique sound. Alex spoke with Ryan(guitar/vocals),about the tour, what it feels like to have a receptive audience,and how the band's excited to come back toNashville.
Newsletter
Interview with Julian Casablancas
2010
Reflecting the dynamictastes of Casablancas himself, \"Phrazes\" is an incendiary mix ofrock, electronic, and new wave, providing a platform forelaborately theatrical stage shows. In anticipation of his upcomingApril 27th show in Nashville, Versus staff writer Alex Daly had thechance to sit down and talk with Julian about his new sound, hisinfluences, and his love of working the crowd.
Newsletter
Blinded by the Great Northern Lights: A revealing look at The White Stripes
2010
The documentarynot only captures fantastic moments of the duo performing atconcerts but other unique parts of the trip in which they performedin buses, cafes, a bowling alley, and the most adorable one of all,for a group of Indian tribal elders.
Newsletter
QA with of Montreal's James Huggins: \Nashville has always been a wild place for us\
2010
[...]on this thing I turn all of the last four albums which[consists of] electronic, dance-pop, very much drum-machineoriented music into straight up rock tunes. Many people have the misconception that it's a new album andthat I just went in with ten hot songs and I recorded them all in aweek, but it's much more like a collection of snapshots, like ascrapbook -- like, \"Here's me at summer camp with my parents in1983,\" and \"Here's me at my college graduation\" ... it's like that,but with songs.\\n
Newsletter