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Nicknamed Mr. Show Business, Sammy Davis Jr. was a consummate performer who sang, danced, and acted on film, television, radio, and the stage for over six decades. In this intimate volume, the entertainment legend's story comes to life through rare family photos and a narrative based on conversations between Davis and his daughter Tracey.

In 2021, teachers indicated they were experiencing feelings of burnout, fatigue, and anxiety due to the COVID-19 pandemic. Morale plunged as teachers’ stress and anxiety skyrocketed. Teachers reported stress levels high enough to impact their work. Black Americans were increasingly showing signs of anxiety and depression related to the aftermath of George Floyd’s murder by a Minneapolis police officer, which was repeatedly shown on news programs and social media. The disproportionately negative impact COVID-19 had on the Black community led the American Psychological Association President to say, “We are living in a racism pandemic.” Black teachers accounted for only 7% of the national teaching force, and surveys of the national teaching community reported one in four teachers considered vacating their positions. This qualitative phenomenological study aimed to understand how Black women educators experienced and coped during the dual pandemics and how the experiences impacted their plans to remain K-12 educators. Using the Strong Black Woman Schema as the theoretical framework, a screening survey and one-on-one interviews were conducted with eighteen Black women educators. The women were employed in K-12 schools between 2020 and 2023 at public, charter, and private schools across four states, including Pennsylvania, New Jersey, Missouri, and South Carolina. The coded findings supported the theoretical framework. Black women educators were self-reliant, high-achieving, independent, and indulgent caregivers throughout the dual pandemics. They also experienced acute stress, anxiety, and depression due mostly to dehumanizing professional catalysts and racial battle fatigue. Most coped through recreational and creative outlets and shared their challenges with close friends, usually other Black women. For some, coping involved alcohol, delta-9- tetrahydrocannabinol (THC), and prescription drugs. Contrary to the Strong Black Woman Schema, many participants sought assistance managing their problems through psychotherapy. Some participants remained passionate about their roles as educators, but for others, professional departure was imminent. They planned to pursue other endeavors like entrepreneurship, pastoral care, acting, sales, mortuary science, or retire. Future research should address dehumanizing professional practices and trauma-informed administrative management styles as the impetus for change.

This ground-breaking, interdisciplinary volume provides an overdue assessment of how infertility has been understood, treated and experienced in different times and places.It brings together scholars from disciplines including history, literature, psychology, philosophy, and the social sciences to create the first large-scale review of recent.

If the risk of disease is not the same for all germline mutations in a given gene, or if there are other familial modifiers of risk in carriers, then family-history-based estimates of average risk for detected mutations in that gene will depend on how carriers are sampled. Risk may also depend on the site or type of mutation. We studied 51 families with strong histories of breast cancer who attended Australian family cancer clinics and in which a germline mutation in BRCA1 or BRCA2 had been identified (28 and 23 families, respectively). Breast cancer risk in carriers was estimated under maximum likelihood theory, using information from all family members including those not tested, with adjustment for ascertainment by conditioning on genotype of the proband and family phenotype. The average cumulative risk of breast cancer for mutations in either BRCA1 or BRCA2 was 27% (95% confidence interval 16-43%) to age 50 and 64% (44-83%) to age 70. When grouped, the incidence in carriers was on average 17 (10-30) times that in non-carriers, independent of gene or mutation type (hazard ratios: 11 (4-29) for BRCA1, 23 (12-43) for BRCA2 (P for difference = 0.23); 13 (6-29) for protein-truncating mutations, 30 (9-104) for missense mutations and 30 (10-90) for splice-site mutations). For missense mutations, this was equivalent to a cumulative risk to age 70 of 83% (40-100%) and was due in part, but not totally, to the missense mutations 300 T>G in BRCA1 and 4486 G>T in BRCA2, which were individually found to be associated with high risk (P<0.001). Mutations in the central region of BRCA1 may be associated with a lower risk. The issue of the pathogenicity of specific variants may be addressed analytically providing there are one or more suitably informative families with that mutation.

AimAssessment of the efficacy of vitamin D replenishment and maintenance doses required to attain optimal levels in boys with Duchenne muscular dystrophy (DMD).Method25(OH)-vitamin D levels and concurrent vitamin D dosage were collected from retrospective case-note review of boys with DMD at the Dubowitz Neuromuscular Centre. Vitamin D levels were stratified as deficient at <25 nmol/L, insufficient at 25–49 nmol/L, adequate at 50–75 nmol/L and optimal at >75 nmol/L.Result617 vitamin D samples were available from 197 boys (range 2–18 years)—69% from individuals on corticosteroids. Vitamin D-naïve boys (154 samples) showed deficiency in 28%, insufficiency in 42%, adequate levels in 24% and optimal levels in 6%. The vitamin D-supplemented group (463 samples) was tested while on different maintenance/replenishment doses. Three-month replenishment of daily 3000 IU (23 samples) or 6000 IU (37 samples) achieved optimal levels in 52% and 84%, respectively. 182 samples taken on 400 IU revealed deficiency in 19 (10%), insufficiency in 84 (47%), adequate levels in 67 (37%) and optimal levels in 11 (6%). 97 samples taken on 800 IU showed deficiency in 2 (2%), insufficiency in 17 (17%), adequate levels in 56 (58%) and optimal levels in 22 (23%). 81 samples were on 1000 IU and 14 samples on 1500 IU, with optimal levels in 35 (43%) and 9 (64%), respectively. No toxic level was seen (highest level 230 nmol/L).ConclusionsThe prevalence of vitamin D deficiency and insufficiency in DMD is high. A 2-month replenishment regimen of 6000 IU and maintenance regimen of 1000–1500 IU/day was associated with optimal vitamin D levels. These data have important implications for optimising vitamin D dosing in DMD.

Research has shown that social determinants of health, healthcare disparities, and historical trauma have contributed to inferior health outcomes for minority groups in the United States compared to their white counterparts. This qualitative research explores how healthcare providers perceive their own unconscious or implicit biases, which could potentially impact patient treatment outcomes. Bias is defined as a lack of objectivity combined with a preference for a particular person, group, or item. Data were collected using a multidisciplinary sample of healthcare treatment providers who participated in semi-structured individual interviews with the researcher. Twenty-six participants were interviewed with the same questions and in similar settings using narrative and critical race theories and critical discourse analysis conceptual framework. Content analysis indicated emerging themes that affected the participants' unconscious or implicit biases, including the environment in which participants were raised, a sense of commitment to community and educational achievement, and reverse bias. Research using self-assessments has consistently revealed that providers have an exaggeratedly positive appraisal of their personal self-awareness and response to bias. Participants in this study tended to underestimate their biases and overestimate their ability to treat patients free of prejudices. Health providers’ attitudes and perceptions within various healthcare settings have substantial implications for the experiences of patients who pursue preventative care vs. emergent care. Results suggest that training providers on culturally responsive patient care approach and increased community engagement will enable them to better understand implicit and explicit biases and thus more effectively meet their patients’ healthcare needs.

On our lengthy drive north from Sussex, I educate my children; 11-year old twins, Nancy and Lola, and Angus, 15, on the joys of Swallows And Amazons, Arthur Ransome's brilliant 1930s novel set in the Lake District. While my adventurous gang would happily spend the night sleeping under tarpaulin in a makeshift camp, their father and I have limits, so we've rented a charming little cottage near the village of Lakeside. Surrounded by peaked hills dusted with late winter snow and deep baize-green valleys curling around huge shimmering bodies of water, it's easy to see how the Lake District has inspired writers, artists and poets for centuries.