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A bstract The ratio R = Γ( K S → πeν ) / Γ( K S → π + π − ) has been measured with a sample of 300 million K S mesons produced in ϕ → K L K S decays recorded by the KLOE experiment at the DAΦNE e + e − collider. K S → πeν events are selected by a boosted decision tree built with kinematic variables and time-of-flight measurements. Data control samples of K L → πeν decays are used to evaluate signal selection efficiencies. With 49647 ± 316 signal events we measure R = (1 . 0421 ± 0 . 0066 stat ± 0 . 0075 syst ) × 10 − 3 . The combination with our previous measurement gives R = (1 . 0338 ± 0 . 0054 stat ± 0 . 0064 syst ) × 10 − 3 . From this value we derive the branching fraction B ( K S → πeν ) = (7 . 153 ± 0 . 037 stat ± 0 . 044 syst ) × 10 − 4 and f + (0) |V us | = 0 . 2170 ± 0 . 009.

A new kind of CPT test for transitions in the neutral kaon system is presented, where the exchange of in and out states (and CP conjugation), required for a direct and genuine CPT test, is performed exploiting the entanglement of the kaon pair produced at a φ-factory. Using this method it would be possible for the first time to directly test the CPT symmetry in transition processes between meson states, rather than comparing masses, lifetimes, or other intrinsic properties of particle and anti-particle states. The proposed test in the neutral kaon system is very clean and fully robust, and might shed light on possible new CPT violating mechanisms, or further improve the precision of the present experimental limits. It could be implemented at the DAΦNE facility in Frascati, where the KLOE-2 experiment can reach a statistical sensitivity of ?CDATA ${\\cal O}({10^{ - 3}})$ ?> O ( 10 − 3 ) on the newly proposed observable quantities.

A bstract Using 1.63 fb −1 of integrated luminosity collected by the KLOE experiment about 7 × 10 4 K S → π ± e ∓ ν decays have been reconstructed. The measured value of the charge asymmetry for this decay is A S = (−4.9 ± 5.7 stat ± 2.6 syst ) × 10 −3 , which is almost twice more precise than the previous KLOE result. The combination of these two measurements gives A S = (−3.8 ± 5.0 stat ± 2.6 syst ) × 10 −3 and, together with the asymmetry of the K L semileptonic decay, provides significant tests of the CPT symmetry. The obtained results are in agreement with CPT invariance.

Using 1.63 fb−1 of integrated luminosity collected by the KLOE experiment about \\(7 10^4\\,K_S ev\\) decays have been reconstructed. The measured value of the charge asymmetry for this decay is AS = (−4.9 ± 5.7stat ± 2.6 syst ) x 10−3 which is almost twice more precise than the previous KLOE result. The combination of these two measurements gives AS = (−3.8 ± 5.0 stat ±2.6syst) x 10−3 and, together with the asymmetry of the KL semileptonic decay, provides significant tests of the CPT symmetry. The obtained results are in agreement with CPT invariance.

Diabetic foot ulcers (DFUs) pose a significant risk for infection and limb loss. Advanced wound therapies including human skin allografts have shown promise in resolving these challenging wounds. The primary objective of this randomised, prospective study was to compare the response of 100 subjects with non‐healing DFUs of which 50 were treated with a cryopreserved bioactive split thickness skin allograft (BSA) (TheraSkin; Misonix,Inc., Farmingdale, NY) compared with 50 subjects treated with standard of care (SOC, collagen alginate dressing) at 12 weeks. Both groups received standardised care that included glucose monitoring, weekly debridement's as appropriate, and an offloading device. The primary endpoint was proportion of full‐thickness wounds healed at 12 weeks, with secondary endpoints including differences in percent area reduction (PAR) at 12 weeks, changes in Semmes‐Weinstein monofilament score, VAS pain, and w‐QoL. The result illustrated in the intent‐to‐treat analysis at 12 weeks showed that 76% (38/50) of the BSA‐treated DFUs healed compared with 36% (18/50) treated with SOC alone (adjusted P = .00056). Mean PAR at 12 weeks was 77.8% in the BSA group compared with 49.6% in the SOC group (adjusted P = .0019). In conclusion, adding BSA to SOC appeared to significantly improve wound healing with a lower incidence of adverse events related to treatment compared with SOC alone.

A bstract We present a measurement of the doubly radiative decay η → π 0 γγ based on a sample of 82 million η mesons produced in the e + e − → ϕ → ηγ process at the Frascati ϕ -factory DAΦNE. From the data analysis, 1246 ± 133 signal events were observed. By normalising the signal to the well-known η → 3 π 0 decay the branching fraction is measured to be (0 . 98 ± 0 . 11 stat ± 0 . 14 syst ) × 10 − 4 . This result agrees with a preliminary KLOE measurement, but is a factor of two smaller than the current world average. Results for d Γ( η → π 0 γγ ) /dM 2 ( γγ ) are also presented and compared with the latest theoretical predictions.

We present a measurement of the doubly radiative decay η → π0γγ based ona sample of 82 million η mesons produced in the e+e− → ϕ → ηγ process at the Frascatiϕ-factory DAΦNE. From the data analysis, 1246 ± 133 signal events were observed. Bynormalising the signal to the well-known η → 3π0 decay the branching fraction B(η → π0γγ) ismeasured to be (0.98 ± 0.11stat ± 0.14syst) × 10−4. This result agrees with a preliminary KLOEmeasurement, but is a factor of two smaller than the current world average. Results for dΓ(η →π0γγ)/dM 2(γγ) are also presented and compared with the latest theoretical predictions.

A bstract The quantum interference between the decays of entangled neutral kaons is studied in the process ϕ → K S K L → π + π − π + π − , which exhibits the characteristic Einstein-Podolsky-Rosen correlations that prevent both kaons to decay into π + π − at the same time. This constitutes a very powerful tool for testing at the utmost precision the quantum coherence of the entangled kaon pair state, and to search for tiny decoherence and CPT violation effects, which may be justified in a quantum gravity framework. The analysed data sample was collected with the KLOE detector at DAΦNE, the Frascati ϕ -factory, and corresponds to an integrated luminosity of about 1.7 fb − 1 , i.e. to about 1 . 7 × 10 9 ϕ → K S K L decays produced. From the fit of the observed ∆ t distribution, being ∆ t the difference of the kaon decay times, the decoherence and CPT violation parameters of various phenomenological models are measured with a largely improved accuracy with respect to previous analyses. The results are consistent with no deviation from quantum mechanics and CPT symmetry, while for some parameters the precision reaches the interesting level at which — in the most optimistic scenarios — quantum gravity effects might show up. They provide the most stringent limits up to date on the considered models.

A bstract Based on an integrated luminosity of 1.61 fb − 1 e + e − collision data collected with the KLOE detector at DAΦNE, the Frascati ϕ -factory, a search for the P - and CP -violating decay η → π + π − has been performed. Radiative ϕ → ηγ decay is exploited to access the η mesons. No signal is observed in the π + π − invariant mass spectrum, and the upper limit on the branching fraction at 90% confidence level is determined to be ℬ( η → π + π − ) < 4 . 9 × 10 − 6 , which is approximately three times smaller than the previous KLOE result. From the combination of these two measurements we get ℬ( η → π + π − ) < 4 . 4 × 10 − 6 at 90% confidence level.

Collapse models provide a theoretical framework for understanding how classical world emerges from quantum mechanics. Their dynamics preserves (practically) quantum linearity for microscopic systems, while it becomes strongly nonlinear when moving towards macroscopic scale. The conventional approach to test collapse models is to create spatial superpositions of mesoscopic systems and then examine the loss of interference, while environmental noises are engineered carefully. Here we investigate a different approach: We study systems that naturally oscillate–creating quantum superpositions–and thus represent a natural case-study for testing quantum linearity: neutrinos, neutral mesons and chiral molecules. We will show how spontaneous collapses affect their oscillatory behavior and will compare them with environmental decoherence effects. We will show that, contrary to what previously predicted, collapse models cannot be tested with neutrinos. The effect is stronger for neutral mesons, but still beyond experimental reach. Instead, chiral molecules can offer promising candidates for testing collapse models.