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Cancer is a problematic global health issue with an extremely high fatality rate throughout the world. The application of various machine learning techniques that have appeared in the field of cancer diagnosis in recent years has provided meaningful insights into efficient and precise treatment decision-making. Due to rapid advancements in sequencing technologies, the detection of cancer based on gene expression data has improved over the years. Different types of cancer affect different parts of the body in different ways. Cancer that affects the mouth, lip, and upper throat is known as oral cancer, which is the sixth most prevalent form of cancer worldwide. India, Bangladesh, China, the United States, and Pakistan are the top five countries with the highest rates of oral cavity disease and lip cancer. The major causes of oral cancer are excessive use of tobacco and cigarette smoking. Many people’s lives can be saved if oral cancer (OC) can be detected early. Early identification and diagnosis could assist doctors in providing better patient care and effective treatment. OC screening may advance with the implementation of artificial intelligence (AI) techniques. AI can provide assistance to the oncology sector by accurately analyzing a large dataset from several imaging modalities. This review deals with the implementation of AI during the early stages of cancer for the proper detection and treatment of OC. Furthermore, performance evaluations of several DL and ML models have been carried out to show that the DL model can overcome the difficult challenges associated with early cancerous lesions in the mouth. For this review, we have followed the rules recommended for the extension of scoping reviews and meta-analyses (PRISMA-ScR). Examining the reference lists for the chosen articles helped us gather more details on the subject. Additionally, we discussed AI’s drawbacks and its potential use in research on oral cancer. There are methods for reducing risk factors, such as reducing the use of tobacco and alcohol, as well as immunization against HPV infection to avoid oral cancer, or to lessen the burden of the disease. Additionally, officious methods for preventing oral diseases include training programs for doctors and patients as well as facilitating early diagnosis via screening high-risk populations for the disease.

Clustered regularly interspaced short palindromic repeat (CRISPR)-based genome editing (GED) technologies have unlocked exciting possibilities for understanding genes and improving medical treatments. On the other hand, Artificial intelligence (AI) helps genome editing achieve more precision, efficiency, and affordability in tackling various diseases, like Sickle cell anemia or Thalassemia. AI models have been in use for designing guide RNAs (gRNAs) for CRISPR-Cas systems. Tools like DeepCRISPR, CRISTA, and DeepHF have the capability to predict optimal guide RNAs (gRNAs) for a specified target sequence. These predictions take into account multiple factors, including genomic context, Cas protein type, desired mutation type, on-target/off-target scores, potential off-target sites, and the potential impacts of genome editing on gene function and cell phenotype. These models aid in optimizing different genome editing technologies, such as base, prime, and epigenome editing, which are advanced techniques to introduce precise and programmable changes to DNA sequences without relying on the homology-directed repair pathway or donor DNA templates. Furthermore, AI, in collaboration with genome editing and precision medicine, enables personalized treatments based on genetic profiles. AI analyzes patients’ genomic data to identify mutations, variations, and biomarkers associated with different diseases like Cancer, Diabetes, Alzheimer’s, etc. However, several challenges persist, including high costs, off-target editing, suitable delivery methods for CRISPR cargoes, improving editing efficiency, and ensuring safety in clinical applications. This review explores AI’s contribution to improving CRISPR-based genome editing technologies and addresses existing challenges. It also discusses potential areas for future research in AI-driven CRISPR-based genome editing technologies. The integration of AI and genome editing opens up new possibilities for genetics, biomedicine, and healthcare, with significant implications for human health.

Immunotherapy has ushered in a new era of cancer treatment, yet cancer remains a leading cause of global mortality. Among various therapeutic strategies, cancer vaccines have shown promise by activating the immune system to specifically target cancer cells. While current cancer vaccines are primarily prophylactic, advancements in targeting tumor-associated antigens (TAAs) and neoantigens have paved the way for therapeutic vaccines. The integration of artificial intelligence (AI) into cancer vaccine development is revolutionizing the field by enhancing various aspect of design and delivery. This review explores how AI facilitates precise epitope design, optimizes mRNA and DNA vaccine instructions, and enables personalized vaccine strategies by predicting patient responses. By utilizing AI technologies, researchers can navigate complex biological datasets and uncover novel therapeutic targets, thereby improving the precision and efficacy of cancer vaccines. Despite the promise of AI-powered cancer vaccines, significant challenges remain, such as tumor heterogeneity and genetic variability, which can limit the effectiveness of neoantigen prediction. Moreover, ethical and regulatory concerns surrounding data privacy and algorithmic bias must be addressed to ensure responsible AI deployment. The future of cancer vaccine development lies in the seamless integration of AI to create personalized immunotherapies that offer targeted and effective cancer treatments. This review underscores the importance of interdisciplinary collaboration and innovation in overcoming these challenges and advancing cancer vaccine development.

With information systems worldwide being attacked daily, analogies from traditional warfare are apt, and deception tactics have historically proven effective as both a strategy and a technique for Defense. Defensive Deception includes thinking like an attacker and determining the best strategy to counter common attack strategies. Defensive Deception tactics are beneficial at introducing uncertainty for adversaries, increasing their learning costs, and, as a result, lowering the likelihood of successful attacks. In cybersecurity, honeypots and honeytokens and camouflaging and moving target defense commonly employ Defensive Deception tactics. For a variety of purposes, deceptive and anti-deceptive technologies have been created. However, there is a critical need for a broad, comprehensive and quantitative framework that can help us deploy advanced deception technologies. Computational intelligence provides an appropriate set of tools for creating advanced deception frameworks. Computational intelligence comprises two significant families of artificial intelligence technologies: deep learning and machine learning. These strategies can be used in various situations in Defensive Deception technologies. This survey focuses on Defensive Deception tactics deployed using the help of deep learning and machine learning algorithms. Prior work has yielded insights, lessons, and limitations presented in this study. It culminates with a discussion about future directions, which helps address the important gaps in present Defensive Deception research.

Parkinson’s disease (PD) is a devastating neurological disease that cannot be identified with traditional plasma experiments, necessitating the development of a faster, less expensive diagnostic instrument. Due to the difficulty of quantifying PD in the past, doctors have tended to focus on some signs while ignoring others, primarily relying on an intuitive assessment scale because of the disease’s characteristics, which include loss of motor control and speech that can be utilized to detect and diagnose this disease. It is an illness that impacts both motion and non-motion functions. It takes years to develop and has a wide range of clinical symptoms and prognoses. Parkinson’s patients commonly display non-motor symptoms such as sleep problems, neurocognitive ailments, and cognitive impairment long before the diagnosis, even though scientists have been working to develop designs for diagnosing and categorizing the disease, only noticeable defects such as movement patterns, speech, or writing skills are offered in this paper. This article provides a thorough analysis of several AI-based ML and DL techniques used to diagnose PD and their influence on developing additional research directions. It follows the guidelines of Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). This review also examines the current state of PD diagnosis and the potential applications of data-driven AI technology. It ends with a discussion of future developments, which aids in filling critical gaps in the current Parkinson’s study.