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"Docherty, J. C"
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Scottish migration since 1750
Scottish Migration since 1750: Reasons and Results begins a fresh chapter in migration studies using new methods and unpublished sources to map the course of Scottish migration between 1750 and 1990. It explains why the Scottish population grew after 1650, why most Scots continued to be female, and the underlying economic reasons for Scottish emigration after 1820. It surveys migration to England, Canada, United States, South Africa, Australia, and New Zealand. It explores their names, marriages, family structures, and religions, and assesses how well they really fared compared to other British migrants. Far from being just another Celtic sob story, this book offers a model about how the histories of other migrant groups might be reappraised.
eBook
Historical dictionary of organized labor
Organized labor is about the collective efforts of employees to improve their economic, social, and political position. It can be studied from many different points of view—historical, economic, sociological, or legal—but it is fundamentally about the struggle for human rights and social justice. As a rule, organized labor has tried to make the world a fairer place. Even though it has only ever covered a minority of employees in most countries, its effects on their political, economic, and social systems have been generally positive. History shows that when organized labor is repressed, the whole society suffers and is made less just.
The Historical Dictionary of Organized Labor looks at the history of organized labor to see where it came from and where it has been. This is done through a chronology, an introductory essay, appendixes, a glossary of terms, and an extensive bibliography. The dictionary section has over 400 cross-referenced entries on most countries, international as well as national labor organizations, major labor unions, leaders, and other aspects of organized labor such as changes in the composition of its membership. This book is an excellent access point for students, researchers, and anyone wanting to know more about organized labor.
eBook
Na+-H+ exchange inhibition at reperfusion is cardioprotective during myocardial ischemia-reperfusion; 31P NMR studies
To help resolve the controversy as to whether or not Na(+)-H+ exchange is functioning during reperfusion of the ischemic myocardium we assessed the effects of dimethylamiloride (DMA, an amiloride analogue possessing selectivity for inhibition of the Na(+)-H+ exchanger) on cardiac function and intracellular pH during ischemia-reperfusion. Studies were performed in the presence of bicarbonate (modified Krebs-Henseleit buffer) or in the nominal absence of bicarbonate (HEPES buffer) in order to determine if similar cardioprotection and effects on intracellular pH were observed in the presence and absence of bicarbonate dependent transport processes. Isovolumic rat hearts were perfused in the Langendorff mode at a constant pressure of 80 mm Hg and subjected to 28 min total global ischemia at 37 degrees C. Intracellular pH was determined from the pH dependent shift of the inorganic phosphate peak in 31P nuclear magnetic resonance spectra. DMA (20 microM) was infused for either 2.5 min before ischemia, for the initial 5 min of reperfusion, or at both time intervals. DMA had no effect on the intracellular pH during ischemia. Intracellular pH returned to pre-ischemic levels within 2.5 min of reperfusion in bicarbonate buffer. This normalization of pH was slower in HEPES perfusate. In both bicarbonate and HEPES perfused hearts all drug dosing regimens caused a significant increase in the recovery of mechanical function after reperfusion and slowed the recovery of intracellular pH during reperfusion. These results suggest that the Na(+)-H+ exchanger is activated during reperfusion of the ischemic myocardium, that this activation of the exchanger contributes to ischemia-reperfusion induced cardiac dysfunction and that administration of an inhibitor of Na(+)-H+ exchange at reperfusion significantly attenuates the deleterious effects of exchanger activation.
Journal Article
A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest
In a randomized trial involving 8014 patients with out-of-hospital cardiac arrest, the use of epinephrine resulted in a significantly higher rate of 30-day survival than placebo but not a higher rate of survival with a favorable neurologic outcome.
Journal Article