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This study aims to add proof to the safety profile of propranolol as first-line choice in treating infantile haemangiomas, in particular related to its cardiac side effects the main hindering reason for parents and physicians to start and comply with treatment. This is a prospective observational and analytic study with a sample of 476 patients diagnosed with infantile haemangioma and treated with systemic propranolol during the time interval January 2011 to December 2021. We studied clinical propranolol adverse events experienced in hospital or outpatient and measured the impact of propranolol on blood pressure and heart rate. This study showed that symptomatic adverse events caused by propranolol were mild and severe adverse events were rare. The most common clinical side effects were paleness, sweating, reduced feeding, and agitation. Only in 28 (5.9%) cases these symptoms were severe enough to review treatment, 1.8% had severe respiratory symptoms, 2.7% experienced hypoglycaemia, and 1.2% had heart-related symptoms. Mean blood pressure reduction with treatment was statistically significant only after achieving the maintenance dose 2 mg/kg body weight. Blood pressure under the 5th percentile was registered in 2.9% of cases, but only four patients had symptomatic hypotension. While heart rate reduction was noticed with the first dose, only two experienced symptomatic bradycardia. We conclude that propranolol is not only an excellent drug in treating infantile haemangioma, but it has also a very safe profile, with mild side effects and very rare severe cardiac adverse events, easily overcome with treatment interruption.

•Mothers in Albania, Nicaragua, Philippines, and Jordan completed a survey.•Influenza vaccine is not routinely given in these countries.•Many mothers were unaware of the disease or vaccine.•Perceived safety was an important predictor of vaccine intentions. Despite a large burden of influenza in middle income countries, pediatric vaccination coverage remains low. The aims of this study were to (1) describe mothers’ knowledge and attitudes about influenza illnesses and vaccination, and (2) identify characteristics associated with mothers’ intent to vaccinate their child. From 2015 to 2017, infants 0–11 months old in Nicaragua, Philippines, Jordan, and Albania were enrolled from community settings and hospitals. Interviewers administered a questionnaire to their mothers. Mothers of infants aged 6–11 months rated their intention (small-to-moderate vs. large chance) to accept pediatric vaccination if it was offered at no-cost. The importance of knowledge, attitudes, and sociodemographic characteristics in predicting influenza vaccination intention was measured as the mean decrease in Gini index when that factor was excluded from 1000 decision trees in a random forest analysis. In total, 1,308 mothers were enrolled from the community setting and 3,286 from the hospital setting. Prevalence of at least some knowledge of influenza illness ranged from 34% in Philippines to 88% in Albania (in the community sample), and between 23% in Philippines to 88% in Jordan (in the hospital sample). In the community sample, most mothers in Albania (69%) and Philippines (58%) would accept the influenza vaccine, and these proportions were higher in the hospital sample for all countries except Albania (48%) (P < 0.0001). Perceived vaccine safety (mean decrease in Gini index = 61) and effectiveness (55), and perceived knowledge of influenza vaccine (45) were the most important predictors of influenza vaccination intention in models that also included country and community versus hospital sample. Intent to vaccinate infants aged 6–11 months in four middle income countries was tied primarily to knowledge of the vaccine and perceptions of vaccine safety and effectiveness. These findings were noted among mothers interviewed in the community and mothers of recently hospitalized infants.

Background/Objectives: Professional competencies and personal mastery are key dimensions for the well-being of health professionals and the quality of care. In physiotherapy, where organizational complexity is common, job satisfaction depends on both clinical skills and resilience. While these aspects have been explored in nursing, evidence for physiotherapists is limited. This study aimed to (1) assess perceived competencies and personal mastery in Italian physiotherapists; (2) analyze their relationship with job satisfaction; and (3) examine the factorial structure of the Multidimensional Scale of Competences. Methods: A cross-sectional study was conducted with 481 physiotherapists working in various care settings. Data were collected using the 25-item Multidimensional Scale of Competences, the 7-item Personal Mastery Scale, and a single job satisfaction item, all on a 5-point Likert scale. Analyses included descriptive statistics, Pearson correlations, logistic regression, and exploratory factor analysis (Principal Component Analysis with five components). Results: Participants had a mean age of 31.1 years (SD = 8.3) and 7.3 years of professional experience (SD = 7.7); gender distribution was balanced. Most held a master’s (44.5%) or bachelor’s degree (36.8%). Job satisfaction was high, with 95% reporting moderate to very high satisfaction. Competencies showed a mean of 4.16 (SD = 0.95; α = 0.86), while Personal Mastery averaged 3.52 (SD = 1.29; α = 0.60). Competencies significantly predicted job satisfaction (OR = 8.37, p = 0.003), whereas Personal Mastery did not. Factor analysis identified five domains—technical–clinical, communicative, collaborative, ethical, and educational—explaining 50.3% of variance. Conclusions: Italian physiotherapists report high competencies and moderate personal mastery. Job satisfaction is strongly linked to competencies, highlighting their central role in professional well-being. Results support the importance of continuous professional development and organizational strategies that enhance competencies and resilience.