Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
1,489
result(s) for
"Edwards, Matthew"
Sort by:
The Rwandan genocide on film : critical essays and interviews
\"The Rwandan genocide remains one of the most shameful events of the 20th century. Many Westerners' understanding of it is based upon the film Hotel Rwanda and Shooting Dogs. Drawing on new scholarship, this collection of essays explores a variety of films and documentaries associated with the Genocide to understand its expression in both Western and Rwandan cinema\"-- Provided by publisher.
Book
Race, Policing, and History — Remembering the Freedom House Ambulance Service
In the 1960s, Pittsburgh’s Freedom House Ambulance Service supplanted the police in a role in which they were not effective, reimagined the role of Black citizens in improving community health, and helped establish national standards for emergency medical care.
Journal Article
So you want to sing rock : a guide for performers
\"Matthew Edwards provides a comprehensive guide for singing rock 'n' roll, covering history, voice science, vocal health, audio technology, technical approaches, and stylistic parameters. This fully updated and expanded edition gives specific advice for a variety of skill levels and for those crossing over from classical or musical theatre\"-- Provided by publisher.
Book
The X-Ray Emission Effectiveness of Plasma Mirrors: Reexamining Power-Law Scaling for Relativistic High-Order Harmonic Generation
Ultrashort pulsed lasers provide uniquely detailed access to the ultrafast dynamics of physical, chemical, and biological systems, but only a handful of wavelengths are directly produced by solid-state lasers, necessitating efficient high-power frequency conversion. Relativistic plasma mirrors generate broadband power-law spectra, that may span the gap between petawatt-class infrared laser facilities and x-ray free-electron lasers; despite substantial theoretical work the ultimate efficiency of this relativistic high-order-harmonic generation remains unclear. We show that the coherent radiation emitted by plasma mirrors follows a power-law distribution of energy over frequency with an exponent that, even in the ultrarelativistic limit, strongly depends on the ratio of laser intensity to plasma density and exceeds the frequently quoted value of −8/3 over a wide range of parameters. The coherent synchrotron emission model, when adequately corrected for the finite width of emitting electron bunches, is not just valid for p-polarized light and thin foil targets, but generally describes relativistic harmonic generation, including at normal incidence and with finite-gradient plasmas. Our numerical results support the
ω
−4/3
scaling of the synchrotron emission model as a limiting efficiency of the process under most conditions. The highest frequencies that can be generated with this scaling are usually restricted by the width of the emitting electron bunch rather than the Lorentz factor of the fastest electrons. The theoretical scaling relations developed here suggest, for example, that with a 20-PW 800-nm driving laser, 1 TW/harmonic can be produced for 1-keV photons.
Journal Article
So you want to sing Rock 'n' Roll : a guide for professionals
\"Rock 'n' roll is a style that was born out of the great American melting pot. An outgrowth of the blues, rock 'n' roll music combines driving rhythms, powerful chords, and lyrics that communicate the human experience to audiences around the world. Although rock singing was once seen as a vulgar use of the human voice and was largely ignored by the academic community, voice teachers and singers around the world have recently taken a professional interest in learning specialized techniques for singing rock 'n' roll. So You Want to Sing Rock 'n' Roll gives readers a comprehensive guide to rock history, voice science, vocal health, audio technology, technical approaches to singing rock, and stylistic parameters for various rock subgenres. Matthew Edwards, assistant professor of voice at Shenandoah Conservatory, provides easy-to-understand explanations of technical concepts, with tips for practical application, and sugg
Book
Determination of RNA structural diversity and its role in HIV-1 RNA splicing
Human immunodeficiency virus 1 (HIV-1) is a retrovirus with a ten-kilobase single-stranded RNA genome. HIV-1 must express all of its gene products from a single primary transcript, which undergoes alternative splicing to produce diverse protein products that include structural proteins and regulatory factors
1
,
2
. Despite the critical role of alternative splicing, the mechanisms that drive the choice of splice site are poorly understood. Synonymous RNA mutations that lead to severe defects in splicing and viral replication indicate the presence of unknown
cis
-regulatory elements
3
. Here we use dimethyl sulfate mutational profiling with sequencing (DMS-MaPseq) to investigate the structure of HIV-1 RNA in cells, and develop an algorithm that we name ‘detection of RNA folding ensembles using expectation–maximization’ (DREEM), which reveals the alternative conformations that are assumed by the same RNA sequence. Contrary to previous models that have analysed population averages
4
, our results reveal heterogeneous regions of RNA structure across the entire HIV-1 genome. In addition to confirming that in vitro characterized
5
alternative structures for the HIV-1 Rev responsive element also exist in cells, we discover alternative conformations at critical splice sites that influence the ratio of transcript isoforms. Our simultaneous measurement of splicing and intracellular RNA structure provides evidence for the long-standing hypothesis
6
–
8
that heterogeneity in RNA conformation regulates splice-site use and viral gene expression.
Dimethyl sulfate mutational profiling with sequencing, combined with the newly developed DREEM algorithm, reveals that heterogeneity of RNA structure in HIV-1 regulates the use of splice sites and expression of viral genes.
Journal Article
Elevated temperature drives kelp microbiome dysbiosis, while elevated carbon dioxide induces water microbiome disruption
Global climate change includes rising temperatures and increased pCO2 concentrations in the ocean, with potential deleterious impacts on marine organisms. In this case study we conducted a four-week climate change incubation experiment, and tested the independent and combined effects of increased temperature and partial pressure of carbon dioxide (pCO2), on the microbiomes of a foundation species, the giant kelp Macrocystis pyrifera, and the surrounding water column. The water and kelp microbiome responded differently to each of the climate stressors. In the water microbiome, each condition caused an increase in a distinct microbial order, whereas the kelp microbiome exhibited a reduction in the dominant kelp-associated order, Alteromondales. The water column microbiomes were most disrupted by elevated pCO2, with a 7.3 fold increase in Rhizobiales. The kelp microbiome was most influenced by elevated temperature and elevated temperature in combination with elevated pCO2. Kelp growth was negatively associated with elevated temperature, and the kelp microbiome showed a 5.3 fold increase Flavobacteriales and a 2.2 fold increase alginate degrading enzymes and sulfated polysaccharides. In contrast, kelp growth was positively associated with the combination of high temperature and high pCO2 'future conditions', with a 12.5 fold increase in Planctomycetales and 4.8 fold increase in Rhodobacteriales. Therefore, the water and kelp microbiomes acted as distinct communities, where the kelp was stabilizing the microbiome under changing pCO2 conditions, but lost control at high temperature. Under future conditions, a new equilibrium between the kelp and the microbiome was potentially reached, where the kelp grew rapidly and the commensal microbes responded to an increase in mucus production.
Journal Article
Trophic downgrading reduces spatial variability on rocky reefs
Trophic downgrading in coastal waters has occurred globally during recent decades. On temperate rocky reefs, this has resulted in widespread kelp deforestation and the formation of sea urchin barrens. We hypothesize that the intact kelp forest communities are more spatially variable than the downgraded urchin barren communities, and that these differences are greatest at small spatial scales where the influence of competitive and trophic interactions is strongest. To address this, benthic community surveys were done in kelp forests and urchin barrens at nine islands spanning 1230 km of the Aleutian Archipelago where the loss of predatory sea otters has resulted in the trophic downgrading of the region’s kelp forests. We found more species and greater total spatial variation in community composition within the kelp forests than in the urchin barrens. Further, the kelp forest communities were most variable at small spatial scales (within each forest) and least variable at large spatial scales (among forests on different islands), while the urchin barren communities followed the opposite pattern. This trend was consistent for different trophic guilds (primary producers, grazers, filter feeders, predators). Together, this suggests that Aleutian kelp forests create variable habitats within their boundaries, but that the communities within these forests are generally similar across the archipelago. In contrast, urchin barrens exhibit relatively low variability within their boundaries, but these communities vary substantially among different barrens across the archipelago. We propose this represents a shift from small-scale biological control to large-scale oceanographic control of these communities.
Journal Article
Magma fragmentation and particle size distributions in low intensity mafic explosions: the July/August 2015 Piton de la Fournaise eruption
Understanding magma fragmentation mechanisms in explosive eruptions is a key requirement for volcanic hazard assessment, eruption management and risk mitigation. This paper focuses on a type case small explosivity eruption (July–August 2015 eruption of Piton de la Fournaise). These eruptions, despite being often overlooked, are exceedingly frequent on local-to-global scales and constitute a significant hazard in vent-proximal areas, which are often populated by guides, tourists and, indeed, volcanologists due to their accessibility. The explosions presented here are ideal cases for the study of the dynamics of magma fragmentation and how it relates to the size distribution of scoria generated at the vent. We documented these events visually and thermally, and characterised the products through sample-return. This allowed us to describe small-scale gas bursts sending ejecta up to 30 m during intermittent lava fountains. Surface tension instabilities and inertial forces played a major role in fragmentation processes and generated particles with coarse-skewed distributions and median diameters ranging from − 8 to − 10 ϕ. However, with time distributions of particles in the most energetic fountains shifted towards more symmetrical shapes as median grains sizes became finer. Analyses of sequences of images demonstrate that the evolution of particle size distributions with time is due to instability of magma droplets and (in-flight) fragmentation.
Journal Article
Impacts of the non-native alga Sargassum horneri on benthic community production in a California kelp forest
The arrival of Sargassum horneri throughout the Southern California Bight and the Baja Peninsula has raised concern regarding kelp forest resilience and ecosystem function following the invasion of this non-native species. To understand how S. horneri impacts native algal abundance and community production, we removed S. horneri from experimental plots over a period of 11 mo. We measured impacts on native algal communities and community productivity using SCUBA surveys and benthic chambers equipped with oxygen, temperature, and light sensors. We observed a nearly 4-fold increase in recruitment of Macrocystis pyrifera and a 9-fold in crease in adult M. pyrifera stipe density in S. horneri removal plots, but no discernable changes in net community production among treatments. We found ephemeral increases in gross community production and community respiration in the non-removal plots that coincided with periods of peak S. horneri biomass. To understand the temporal dynamics of community production, we deployed benthic chambers across a rocky reef dominated by S. horneri. Here, temporal variation in community production was most strongly related to corresponding variation in water temperature and changes in S. horneri biomass related to its annual lifecycle. Overall, our study indicates that S. horneri presence contributed to ephemeral increases in gross community production and community respiration, but it did not affect net community production. Moreover, S. horneri removal can lead to increases in native algal abundances given favorable abiotic conditions. We suggest that S. horneri thrives in a disturbed ecosystem rather than being a driver of ecosystem change.
Journal Article