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Science diplomacy is a rapidly growing field in foreign policy and international relations, gaining even greater importance since the onset of the Covid-19 pandemic. This study explores the substantial role of science diplomacy and international institutions in promoting coordinated efforts during Jordan's response to the pandemic. It examines science diplomacy within the country and its increasing significance in addressing global challenges, with particular emphasis on its contributions to health diplomacy amid the pandemic. The researcher adopts a qualitative research methodology guided by a case study approach. Data were collected from various resources, including journal articles, official international and domestic reports, news reports, and website documents. The thematic analysis of the data highlights the crucial role of Jordan's international collaboration in its response to Covid-19. Notably, international institutions such as WHO, GAVI, CEPI, UNICEF, USAID, EU, and the World Bank played instrumental roles in supporting Jordan's efforts in combating the pandemic.