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"Ende, Michael"
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مومو، أو، حكاية سارقي الوقت الغريبة والطفلة التى أعادت الوقت المسروق للبشرية
\"مومو رواية أسطورية\" تدور حول \"لغز الزمن\" هذا اللغز الذي يمكن أن يشغل بال الصغار والكبار على السواء ومن يتتبع تفاصيلها يلحظ أنها قد حدثت في مملكة الخيال التي تقع في \"اللامكان\" و\"اللازمان\" ولكنه لا تحكي عن السحرة والجان لكنها تنهل لغتها التعبيرية من حياتنا المعاصرة وهناك شركة يملكها \"رجال الظلال\" أو \"السادة الرماديون\" يحرضون البشر على توفير وقتهم ولكنهم في الحقيقة يحتالون عليهم ويسرقون وقتهم والوقت يعني الحياة والحياة مقرها القلب الذي يدق معدودة في إطار الزمن الموعود.
Book
مومو : (رواية أسطورية)
\"مومو رواية أسطورية\" تدور حول \"لغز الزمن\" هذا اللغز الذي يمكن أن يشغل بال الصغار والكبار على السواء ومن يتتبع تفاصيلها يلحظ أنها قد حدثت في مملكة الخيال التي تقع في \"اللامكان\" و\"اللازمان\" ولكنه لا تحكي عن السحرة والجان لكنها تنهل لغتها التعبيرية من حياتنا المعاصرة وهناك شركة يملكها \"رجال الظلال\" أو \"السادة الرماديون\" يحرضون البشر على توفير وقتهم ولكنهم في الحقيقة يحتالون عليهم ويسرقون وقتهم والوقت يعني الحياة والحياة مقرها القلب الذي يدق معدودة في إطار الزمن الموعود.
Book
Anger and violence: A parent's role
We commonly seek a diagnosis -- attention deficit / hyperactivity disorder, oppositional defiant disorder, bipolar disorder -- as a guide to recommended treatment. 3. We know that violent media exposure to children who are already angry increases their risk of violent behavior. Is your child watching violent shows or playing violent video games? Yes, wrestling shows included. 5. Are you involved with other parents in your neighborhood to minimize the risk of violent behavior in your child's environment? A child hearing violent confrontations or gunshots at night becomes either anxious or apathetic about violence.
Newspaper Article
The neverending story
Shy, awkward Bastian is amazed to discover that he has become a character in the mysterious book he is reading and that he has an important mission to fulfill.
Book
The night of wishes, or, the satanarchaeolidealcohellish notion potion
\"It's 5 pm on New Year's Eve in the Villa Nightmare, and as Shadow Sorcery Minister Beelzebub Preposteror's thumb-striking clock counts down each hour with an 'Ouch!,' Minister Preposteror draws closer to missing his midnight deadline forfulfilling his annual quota of evil deeds and being 'foreclosed.' Up against a tight deadline and threats from His Hellish Excellency, the Minister of Pitch Darkness himself, Preposteror has all but given up when the arrival of an unexpected visitor promises hope: his aunt, the witch Tyrannia Vampirella, who proposes that they work together to brew the Notion Potion, a powerful formula that will grant all their evil wishes\"-- Provided by publisher.
Book
A proteome-wide atlas of lysine-reactive chemistry
Recent advances in chemical proteomics have begun to characterize the reactivity and ligandability of lysines on a global scale. Yet, only a limited diversity of aminophilic electrophiles have been evaluated for interactions with the lysine proteome. Here, we report an in-depth profiling of >30 uncharted aminophilic chemotypes that greatly expands the content of ligandable lysines in human proteins. Aminophilic electrophiles showed disparate proteomic reactivities that range from selective interactions with a handful of lysines to, for a set of dicarboxaldehyde fragments, remarkably broad engagement of the covalent small-molecule–lysine interactions captured by the entire library. We used these latter ‘scout’ electrophiles to efficiently map ligandable lysines in primary human immune cells under stimulatory conditions. Finally, we show that aminophilic compounds perturb diverse biochemical functions through site-selective modification of lysines in proteins, including protein–RNA interactions implicated in innate immune responses. These findings support the broad potential of covalent chemistry for targeting functional lysines in the human proteome.A deep chemical proteomic investigation of diverse aminophilic electrophiles has identified ligandable lysines across a wide range of human proteins. The proteins cover different functional and structural classes, and the aminophilic electrophiles include compounds that disrupt protein–protein and protein–RNA interactions. This dataset provides a proteome-wide atlas of lysine-reactive chemistry.
Journal Article