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"Epstein, Mark"
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Rapture and Melancholy
The first publication of Edna St. Vincent Millay's private, intimate diaries, providing \"a candid self-portrait of the 'bad girl of American letters'\" (Kirkus Reviews) \"Endlessly intriguing and illuminating. The publication of Edna St. Vincent Millay's diaries is a major literary event, providing astonishing insight into the great poet's art and life.\"-Chloe Honum, author of The Tulip-Flame The English author Thomas Hardy proclaimed that America had two great attractions: the skyscraper, and the poetry of Edna St. Vincent Millay. In these diaries the great American poet illuminates not only her literary genius, but her life as a devoted daughter, sister, wife, and public heroine; and finally as a solitary, tragic figure. This is the first publication of the diaries she kept from adolescence until middle age, between 1907 and 1949, focused on her most productive years. Who was the girl who wrote \"Renascence,\" that marvel of early twentieth-century poetry? What trauma or spiritual journey inspired the poem? And after such celebrity why did she vanish into near seclusion after 1940? These questions hover over the life and work, and trouble biographers and readers alike. Intimate, eloquent, these confessions and keen observations provide the key to understanding Millay's journey from small-town obscurity to world fame, and the tragedy of her demise.
eBook
Ocean life in the time of dinosaurs
\"A richly illustrated, trade-science book about marine reptiles from the Paleozoic and Mesozoic eras and their modern descendants. A translation from the French publisher, Belin (World English rights)\"-- Provided by publisher.
Book
Psychotherapy without the Self
Immersed in Buddhist psychology prior to studying Western psychiatry, Dr. Mark Epstein first viewed Western therapeutic approaches through the lens of the East. This posed something of a challenge. Although both systems promise liberation through self-awareness, the central tenet of Buddha's wisdom is the notion of no-self, while the central focus of Western psychotherapy is the self. This book, which includes writings from the past twenty-five years, wrestles with the complex relationship between Buddhism and psychotherapy and offers nuanced reflections on therapy, meditation, and psychological and spiritual development.
A best-selling author and popular speaker, Epstein has long been at the forefront of the effort to introduce Buddhist psychology to the West. His unique background enables him to serve as a bridge between the two traditions, which he has found to be more compatible than at first thought. Engaging with the teachings of the Buddha as well as those of Freud and Winnicott, he offers a compelling look at desire, anger, and insight and helps reinterpret the Buddha's Four Noble Truths and central concepts such as egolessness and emptiness in the psychoanalytic language of our time.
eBook
Ghosts of girlfriends past
A bachelor is haunted by the ghosts of his past girlfriends at his younger brother's wedding.
DVD
Paraplegia prevention in aortic aneurysm repair by thoracoabdominal staging with ‘minimally invasive staged segmental artery coil embolisation’ (MIS²ACE): trial protocol for a randomised controlled multicentre trial
IntroductionSpinal cord injury (SCI) including permanent paraplegia constitutes a common complication after repair of thoracoabdominal aortic aneurysms. The staged-repair concept promises to provide protection by inducing arteriogenesis so that the collateral network can provide a robust blood supply to the spinal cord after intervention. Minimally invasive staged segmental artery coil embolisation (MIS2ACE) has been proved recently to be a feasible enhanced approach to staged repair.Methods and analysisThis randomised controlled trial uses a multicentre, multinational, parallel group design, where 500 patients will be randomised in a 1:1 ratio to standard aneurysm repair or to MIS2ACE in 1–3 sessions followed by repair. Before randomisation, physicians document whether open or endovascular repair is planned. The primary endpoint is successful aneurysm repair without substantial SCI 30 days after aneurysm repair. Secondary endpoints include any form of SCI, mortality (up to 1 year), length of stay in the intensive care unit, costs and quality-adjusted life years. A generalised linear mixed model will be used with the logit link function and randomisation arm, mode of repair (open or endovascular repair), the Crawford type and the European System for Cardiac Operative Risk Evaluation (euroSCORE) II as fixed effects and the centre as a random effect. Safety endpoints include kidney failure, respiratory failure and embolic events (also from debris). A qualitative study will explore patient perceptions.Ethics and disseminationThis trial has been approved by the lead Ethics Committee from the University of Leipzig (435/17-ek) and will be reviewed by each of the Ethics Committees at the trial sites. A dedicated project is coordinating communication and dissemination of the trial.Trial registration numberNCT03434314.
Journal Article
The Impact of Cirrhosis on CD4+ T Cell Counts in HIV-Seronegative Patients
Background.Studies of the progression liver fibrosis in human immunodeficiency virus (HIV) and hepatitis C virus-coinfected patients suggest that cirrhosis is associated with immunosuppression, as measured by low absolute CD4+ T cell counts. However, we hypothesized that, in patients with advanced liver disease, low CD4+ T cell counts may occur secondary to portal hypertension and splenic sequestration, regardless of the presence or absence of HIV infection. Methods.Sixty HIV-seronegative outpatients with cirrhosis were enrolled during the period 2001–2003 in a prospective, cross-sectional study of the association between liver disease and CD4+ T cell counts and percentages. Demographic characteristics, liver disease-related characteristics, and laboratory results—including CD4+ T cell parameters—were collected. Results.A total of 39 patients (65%) had a low CD4+ T cell count; 26 patients (43%) and 4 patients (7%) had CD4+ T cell counts <350 and <200 cells/mm3, respectively. Abnormal CD4+ T cell counts were associated with splenomegaly (P = .03), thrombocytopenia (P = .002), and leukopenia (P < .001). The percentage of CD4+ T cells was normal in 95% of patients who had a low absolute CD4+ T cell count. CD4+ T cell counts were significantly lower among cirrhotic patients than among 7638 HIV-seronegative historic control subjects without liver disease. Conclusions.Cirrhosis is associated with low CD4+ T cell counts in the absence of HIV infection. Discordance between low absolute CD4+ T cell counts and normal CD4+ T cell percentages may be attributable to portal hypertension and splenic sequestration. Our findings have significant implications for the use and interpretation of absolute CD4+ T cell counts in HIV-infected patients with advanced liver disease.
Journal Article
TOTalitarian ARTs
This collection represents a tool to broaden and deepen our geographical, institutional, and historical understanding of the term totalitarianism. Is totalitarianism only found in 'other' societies? How come, then, it emerged historically in 'ours' first? How come it developed in so many countries either in Western Europe (Italy, Germany, Portugal, and Spain) or under implicit Western forms of coercion (Latin America)? How do relations between individual(s), mass and the visual arts relate to totalitarian trends? These are among the questions this book asks about totalitarianism.The volume does not impose a 'one size fits all' interpretation, but opens new spaces for debate on the connection between the visual arts and mass-culture in totalitarian societies. From the Mediterranean to Scandinavia, from Western Europe to Latin America, from the fascism of the early 20th century to contemporary forms of totalitarian control, and from cinema to architecture, the chapters included in TotArt bring expertise, historical sensibility and political awareness to bear on this varied range of phenomena.This collection offers international contributions on visual, performing and plastic arts. The chapters range from examination of comics to study of YouTube videos and American newsreels, from Italian, Spanish, Portuguese, and Uruguayan cinemas to more contemporary American films and TV series, from painters and sculptors to the study of urban spaces.
eBook